| Identification |
|---|
| HMDB Protein ID
| CDBP04557 |
| Secondary Accession Numbers
| Not Available |
| Name
| U4/U6 small nuclear ribonucleoprotein Prp4 |
| Description
| Not Available |
| Synonyms
|
- PRP4 homolog
- U4/U6 snRNP 60 kDa protein
- WD splicing factor Prp4
- hPrp4
|
| Gene Name
| PRPF4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in RNA splicing |
| Specific Function
| Involved in pre-mRNA splicing |
| GO Classification
|
| Process |
| rna metabolic process |
| metabolic process |
| macromolecule metabolic process |
| cellular macromolecule metabolic process |
| rna processing |
| rna splicing |
|
| Cellular Location
|
- Nucleus speckle
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9q31-q33 |
| SNPs
| PRPF4 |
| Gene Sequence
|
>1569 bp
ATGGCTTCCTCGCGAGCCTCTTCCACGCAGGCAACCAAAACTAAAGCACCCGACGACTTA
GTTGCTCCGGTCGTGAAGAAACCACACATCTATTATGGAAGTTTGGAAGAGAAGGAGAGG
GAGCGTCTGGCCAAAGGAGAGTCTGGGATTTTGGGGAAAGACGGACTTAAAGCAGGGATC
GAAGCTGGAAATATTAATATAACCTCTGGAGAAGTGTTTGAAATTGAAGAGCATATCAGC
GAGCGACAGGCAGAAGTATTGGCTGAGTTTGAGAGAAGGAAGCGAGCCCGGCAGATCAAT
GTTTCCACAGATGACTCAGAGGTCAAAGCTTGCCTTAGAGCCTTGGGGGAACCCATCACA
CTTTTTGGAGAGGGTCCTGCTGAAAGAAGAGAAAGGTTAAGAAATATCCTCTCAGTTGTC
GGTACTGATGCCTTGAAAAAGACCAAAAAGGATGATGAGAAGTCTAAAAAGTCCAAAGAA
GAGTATCAGCAAACCTGGTATCATGAAGGACCAAATAGCTTGAAGGTGGCAAGACTATGG
ATTGCTAATTATTCGTTGCCCAGGGCAATGAAACGCTTGGAAGAGGCCCGACTCCATAAG
GAGATTCCTGAGACAACAAGGACCTCCCAGATGCAAGAGCTGCACAAGTCTCTCCGGTCT
TTGAATAATTTTTGCAGTCAGATTGGGGATGATCGGCCTATCTCCTACTGTCACTTTAGT
CCCAATTCCAAGATGCTGGCCACAGCTTGTTGGAGTGGGCTTTGCAAGCTCTGGTCTGTT
CCTGATTGCAACCTCCTTCACACTCTTCGAGGGCATAACACAAATGTAGGAGCAATTGTA
TTCCATCCCAAATCCACTGTCTCCTTGGACCCAAAAGATGTCAACCTGGCCTCTTGTGCG
GCTGATGGCTCTGTGAAGCTTTGGAGTCTCGACAGTGATGAACCAGTGGCAGATATTGAA
GGCCATACAGTGCGTGTGGCGCGGGTAATGTGGCATCCTTCAGGACGTTTCCTGGGCACC
ACCTGCTATGACCGTTCATGGCGCTTATGGGATTTGGAGGCTCAAGAGGAGATCCTGCAT
CAGGAAGGCCATAGCATGGGTGTGTATGACATTGCCTTCCATCAAGATGGCTCTTTGGCT
GGCACTGGGGGACTGGATGCATTTGGTCGAGTTTGGGACCTACGCACAGGACGTTGTATC
ATGTTCTTAGAAGGCCACCTGAAAGAAATCTATGGAATAAATTTCTCCCCCAATGGCTAT
CACATTGCAACCGGCAGTGGTGACAACACCTGCAAAGTGTGGGACCTCCGACAGCGGCGT
TGCGTCTACACCATCCCTGCTCATCAGAACTTAGTGACTGGTGTCAAGTTTGAGCCTATC
CATGGGAACTTCTTGCTTACTGGTGCCTATGATAACACAGCCAAGATCTGGACGCACCCA
GGCTGGTCCCCGCTGAAGACTCTGGCTGGCCACGAAGGCAAAGTGATGGGCCTAGATATT
TCTTCCGATGGGCAGCTCATAGCCACTTGCTCATATGACAGGACCTTCAAGCTGTGGATG
GCTGAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 522 |
| Molecular Weight
| 58448.7 |
| Theoretical pI
| 7.44 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>U4/U6 small nuclear ribonucleoprotein Prp4
MASSRASSTQATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGI
EAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPIT
LFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLW
IANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFS
PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCA
ADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH
QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGY
HIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHP
GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
|
| External Links |
|---|
| GenBank ID Protein
| 24431950 |
| UniProtKB/Swiss-Prot ID
| O43172 |
| UniProtKB/Swiss-Prot Entry Name
| PRP4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_004697.3 |
| GeneCard ID
| PRPF4 |
| GenAtlas ID
| PRPF4 |
| HGNC ID
| HGNC:17349 |
| References |
|---|
| General References
| Not Available |