| Identification |
|---|
| HMDB Protein ID
| CDBP04554 |
| Secondary Accession Numbers
| Not Available |
| Name
| Microtubule-associated serine/threonine-protein kinase-like |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| MASTL |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein serine/threonine kinase activity |
| Specific Function
| Putative serine/threonine kinase which may be involved in megakaryocyte differentiation |
| GO Classification
|
| Function |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| Process |
| protein amino acid phosphorylation |
| phosphorylation |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10p12.1 |
| SNPs
| MASTL |
| Gene Sequence
|
>2640 bp
ATGGATCCCACCGCGGGAAGCAAGAAGGAGCCTGGAGGAGGCGCGGCGACTGAGGAGGGC
GTGAATAGGATCGCAGTGCCAAAACCGCCCTCCATTGAGGAATTCAGCATAGTGAAGCCC
ATTAGCCGGGGCGCCTTCGGGAAAGTGTATCTGGGGCAGAAAGGCGGCAAATTGTATGCA
GTAAAGGTTGTTAAAAAAGCAGACATGATCAACAAAAATATGACTCATCAGGTCCAAGCT
GAGAGAGATGCACTGGCACTAAGCAAAAGCCCATTCATTGTCCATTTGTATTATTCACTG
CAGTCTGCAAACAATGTCTACTTGGTAATGGAATATCTTATTGGGGGAGATGTCAAGTCT
CTCCTACATATATATGGTTATTTTGATGAAGAGATGGCTGTGAAATATATTTCTGAAGTA
GCACTGGCTCTAGACTACCTTCACAGACATGGAATCATCCACAGGGACTTGAAACCGGAC
AATATGCTTATTTCTAATGAGGGTCATATTAAACTGACGGATTTTGGCCTTTCAAAAGTT
ACTTTGAATAGAGATATTAATATGATGGATATCCTTACAACACCATCAATGGCAAAACCT
AGACAAGATTATTCAAGAACCCCAGGACAAGTGTTATCGCTTATCAGCTCGTTGGGATTT
AACACACCAATTGCAGAAAAAAATCAAGACCCTGCAAACATCCTTTCAGCCTGTCTGTCT
GAAACATCACAGCTTTCTCAAGGACTCGTATGCCCTATGTCTGTAGATCAAAAGGACACT
ACGCCTTATTCTAGCAAATTACTAAAATCATGTCTTGAAACAGTTGCCTCCAACCCAGGA
ATGCCTGTGAAGTGTCTAACTTCTAATTTACTCCAGTCTAGGAAAAGGCTGGCCACATCC
AGTGCCAGTAGTCAATCCCACACCTTCATATCCAGTGTGGAATCAGAATGCCACAGCAGT
CCCAAATGGGAAAAAGATTGCCAGGAAAGTGATGAAGCATTGGGCCCAACAATGATGAGT
TGGAATGCAGTTGAAAAGTTATGCGCAAAATCTGCAAATGCCATTGAGACGAAAGGTTTC
AATAAAAAGGATCTGGAGTTAGCTCTTTCTCCCATTCATAACAGCAGTGCCCTTCCCACC
ACTGGACGCTCTTGTGTAAACCTTGCTAAAAAATGCTTCTCTGGGGAAGTTTCTTGGGAA
GCAGTAGAACTGGATGTAAATAATATAAATATGGACACTGACACAAGTCAGTTAGGTTTC
CATCAGTCAAATCAGTGGGCTGTGGATTCTGGTGGGATATCTGAAGAGCACCTTGGGAAA
AGAAGTTTAAAAAGAAATTTTGAGTTGGTTGACTCCAGTCCTTGTAAAAAAATTATACAG
AATAAAAAAACTTGTGTAGAGTATAAGCATAACGAAATGACAAATTGTTATACAAATCAA
AATACAGGCTTAACAGTTGAAGTGCAGGACCTTAAGCTATCAGTGCACAAAAGTCAACAA
AATGACTGTGCTAATAAGGAGAACATTGTCAATTCTTTTACTGATAAACAACAAACACCA
GAAAAATTACCTATACCAATGATAGCAAAAAACCTTATGTGTGAACTCGATGAAGACTGT
GAAAAGAATAGTAAGAGGGACTACTTAAGTTCTAGTTTTCTATGTTCTGATGATGATAGA
GCTTCTAAAAATATTTCTATGAACTCTGATTCATCTTTTCCTGGAATTTCTATAATGGAA
AGTCCATTAGAAAGTCAGCCCTTAGATTCAGATAGAAGCATCAAAGAATCCTCTTTTGAA
GAATCAAATATTGAAGATCCACTTATTGTAACACCAGATTGCCAAGAAAAGACCTCACCA
AAAGGTGTCGAGAACCCTGCTGTACAAGAGAGTAACCAAAAAATGTTAGGTCCTCCTTTG
GAGGTGCTGAAAACGTTAGCCTCTAAAAGAAATGCTGTTGCTTTTCGAAGTTTTAACAGT
CATATTAATGCATCCAATAACTCAGAACCATCCAGAATGAACATGACTTCTTTAGATGCA
ATGGATATTTCGTGTGCCTACAGTGGTTCATATCCCATGGCTATAACCCCTACTCAAAAA
AGAAGATCCTGTATGCCACATCAGCAGACCCCAAATCAGATCAAGTCGGGAACTCCATAC
CGAACTCCGAAGAGTGTGAGAAGAGGGGTGGCCCCCGTTGATGATGGGCGAATTCTAGGA
ACCCCAGACTACCTTGCACCTGAGCTGTTACTAGGCAGGGCCCATGGTCCTGCGGTAGAC
TGGTGGGCACTTGGAGTTTGCTTGTTTGAATTTCTAACAGGAATTCCCCCTTTCAATGAT
GAAACACCACAACAAGTATTCCAGAATATTCTGAAAAGAGATATCCCTTGGCCAGAAGGT
GAAGAAAAGTTATCTGATAATGCTCAAAGTGCAGTAGAAATACTTTTAACCATTGATGAT
ACAAAGAGAGCTGGAATGAAAGAGCTAAAACGTCATCCTCTCTTCAGTGATGTGGACTGG
GAAAATCTGCAGCATCAGACTATGCCTTTCATCCCCCAGCCAGATGATGAAACAGATACC
TCCTATTTTGAAGCCAGGAATACTGCTCAGCACCTGACTGTATCTGGATTTAGTCTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 879 |
| Molecular Weight
| 97318.1 |
| Theoretical pI
| 5.84 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Microtubule-associated serine/threonine-protein kinase-like
MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
|
| External Links |
|---|
| GenBank ID Protein
| 288806587 |
| UniProtKB/Swiss-Prot ID
| Q96GX5 |
| UniProtKB/Swiss-Prot Entry Name
| MASTL_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001172303.1 |
| GeneCard ID
| MASTL |
| GenAtlas ID
| MASTL |
| HGNC ID
| HGNC:19042 |
| References |
|---|
| General References
| Not Available |