| Identification |
|---|
| HMDB Protein ID
| CDBP04517 |
| Secondary Accession Numbers
| Not Available |
| Name
| LYN protein |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| LYN |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate |
| GO Classification
|
| Function |
| protein tyrosine kinase activity |
| non-membrane spanning protein tyrosine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein binding |
| protein kinase activity |
| Process |
| peptidyl-tyrosine phosphorylation |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| intracellular signaling pathway |
| signaling |
| signaling pathway |
| phosphorylation |
| phosphorus metabolic process |
| phosphate metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:8 |
| Locus
| 8q13 |
| SNPs
| LYN |
| Gene Sequence
|
>1750 bp
AGTTCCTCTCCCGCCGCGCCGGGCCGCGCTGCCGCTCGCTCCCCGGCCGTGGCGCCTCCG
GGCCAGACGCGCTGCAGCCTCCAGCCCGCGGCAAGCGGGGCGGCCGCGCCACCCCCGGCC
CCGCGCCAGCAGCCCCTCGCCGCGCGTCCAGCGTTCCCGGCCAGCAGCCTCCCCATACGC
AGGTCCTGCTGGGCCGCCCCGTCGCGCCCCCCACTCTGAACTCAAGTCACCGTGGAGCTC
CGCCGCCCCGAAACTTTCACCGCGAGCGGGAAATATGGGATGTATAAAATCAAAAGGGAA
AGACAGCTTGAGTGACGATGGAGTAGATTTGAAGACTCAACCAGTTCCAGAATCTCAGCT
TTTACCTGGACAGAGGTTTCAAACTAAAGATCCAGAGGAACAAGGAGACATTGTGGTAGC
CTTGTACCCCTATGATGGCATCCACCCGGACGACTTGTCTTTCAAGAAAGGAGAGAAGAT
GAAAGTCCTGGAGGAGCATGGAGAATGGTGGAAAGCAAAGTCCCTTTTAACAAAAAAAGA
AGGCTTCATCCCCAGCAACTATGTGGCCAAACTCAACACCTTAGAAACAGAAGAGTGGTT
TTTCAAGGATATAACCAGGAAGGACGCAGAAAGGCAGCTTTTGGCACCAGGAAATAGCGC
TGGAGCTTTCCTTATTAGAGAAAGTGAAACATTAAAAGGAAGCTTCTCTCTGTCTGTCAG
AGACTTTGACCCTGTGCATGGTGATGTTATTAAGCACTACAAAATTAGAAGTCTGGATAA
TGGGGGCTATTACATCTCTCCACGAATCACTTTTCCCTGTATCAGCGACATGATTAAACA
TTACCAAAAGCAGGCAGATGGCTTGTGCAGAAGATTGGAGAAGGCTTGTATTAGTCCCAA
GCCACAGAAGCCATGGGATAAAGATGCCTGGGAGATCCCCCGGGAGTCCATCAAGTTGGT
GAAAAGGCTTGGCGCTGGGCAGTTTGGGGAAGTCTGGATGGGTTACTATAACAACAGTAC
CAAGGTGGCTGTGAAAACCCTGAAGCCAGGAACTATGTCTGTGCAAGCCTTCCTGGAAGA
AGCCAACCTCATGAAGACCCTGCAGCATGACAAGCTCGTGAGGCTCTACGCTGTGGTCAC
CAGGGAGGAGCCCATTTACATCATCACCGAGTACATGGCCAAGGGCAGTTTGCTGGATTT
CCTGAAGAGCGATGAAGGTGGCAAAGTGCTGCTTCCAAAGCTCATTGACTTTTCTGCTCA
GATTGCAGAGGGAATGGCATACATCGAGCGGAAGAACTACATTCACCGGGACCTGCGAGC
AGCTAATGTTCTGGTCTCCGAGTCACTCATGTGCAAAATTGCAGATTTTGGCCTTGCTAG
AGTAATTGAAGATAATGAGTACACAGCAAGGGAAGGTGCTAAGTTCCCTATTAAGTGGAC
GGCTCCAGAAGCAATCAACTTTGGATGTTTCACTATTAAGTCTGATGTGTGGTCCTTTGG
AATCCTCCTATACGAAATTGTCACCTATGGGAAAATTCCCTACCCAGGGAGAACTAATGC
CGACGTGATGACCGCCCTGTCCCAGGGCTACAGGATGCCCCGTGTGGAGAACTGCCCAGA
TGAGCTCTATGACATTATGAAAATGTGCTGGAAAGAAAAGGCAGAAGAGAGACCAACGTT
TGACTACTTACAGAGCGTCCTGGATGATTTCTACACAGCCACGGAAGGGCAATACCAGCA
GCAGCCTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 582 |
| Molecular Weight
| 65807.9 |
| Theoretical pI
| 9.48 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>LYN protein
VPLPPRRAALPLAPRPWRLRARRAAASSPRQAGRPRHPRPRASSPSPRVQRSRPAASPYA
GPAGPPRRAPHSELKSPWSSAAPKLSPRAGNMGCIKSKGKDSLSDDGVDLKTQPVPESQL
LPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKE
GFIPSNYVAKLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVR
DFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPK
PQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEE
ANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQ
IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT
APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPD
ELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP
|
| External Links |
|---|
| GenBank ID Protein
| 37589566 |
| UniProtKB/Swiss-Prot ID
| Q6NUK7 |
| UniProtKB/Swiss-Prot Entry Name
| Q6NUK7_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC059394 |
| GeneCard ID
| LYN |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |