| Identification |
| HMDB Protein ID
| CDBP04510 |
| Secondary Accession Numbers
| Not Available |
| Name
| EPH receptor A8 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| EPHA8 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in ephrin receptor activity |
| Specific Function
| Not Available |
| GO Classification
|
| Component |
| integral to membrane |
| integral to plasma membrane |
| membrane |
| cell part |
| membrane part |
| intrinsic to membrane |
| Function |
| protein tyrosine kinase activity |
| transmembrane receptor protein tyrosine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| ephrin receptor activity |
| protein binding |
| protein kinase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| enzyme linked receptor protein signaling pathway |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| phosphorylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 1p36.12 |
| SNPs
| EPHA8 |
| Gene Sequence
|
>1488 bp
ATGGCCCCCGCCCGGGGCCGCCTGCCCCCTGCGCTCTGGGTCGTCACGGCCGCGGCGGCG
GCGGCCACCTGCGTGTCCGCGGCGCGCGGCGAAGTGAATTTGCTGGACACGTCGACCATC
CACGGGGACTGGGGCTGGCTCACGTATCCGGCTCATGGGTGGGACTCCATCAACGAGGTG
GACGAGTCCTTCCAGCCCATCCACACGTACCAGGTTTGCAACGTCATGAGCCCCAACCAG
AACAACTGGCTGCGCACGAGCTGGGTCCCCCGAGACGGCGCCCGGCGCGTCTATGCTGAG
ATCAAGTTTACCCTGCGCGACTGCAACAGCATGCCTGGTGTGCTGGGCACCTGCAAGGAG
ACCTTCAACCTCTACTACCTGGAGTCGGACCGCGACCTGGGGGCCAGCACACAAGAAAGC
CAGTTCCTCAAAATCGACACCATTGCGGCCGACGAGAGCTTCACAGGTGCCGACCTTGGT
GTGCGGCGTCTCAAGCTCAACACGGAGGTGCGCAGTGTGGGTCCCCTCAGCAAGCGCGGC
TTCTACCTGGCCTTCCAGGACATAGGTGCCTGCCTGGCCATCCTCTCTCTCCGCATCTAC
TATAAGAAGTGCCCTGCCATGGTGCGCAATCTGGCTGCCTTCTCGGAGGCAGTGACGGGG
GCCGACTCGTCCTCACTGGTGGAGGTGAGGGGCCAGTGCGTGCGGCACTCAGAGGAGCGG
GACACACCCAAGATGTACTGCAGCGCGGAGGGCGAGTGGCTCGTGCCCATCGGCAAATGC
GTGTGCAGTGCCGGCTACGAGGAGCGGCGGGATGCCTGTGTGGCCTGTGAGCTGGGCTTC
TACAAGTCAGCCCCTGGGGACCAGCTGTGTGCCCGCTGCCCTCCCCACAGCCACTCCGCA
GCTCCAGCCGCCCAAGCCTGCCACTGTGACCTCAGCTACTACCGTGCAGCCCTGGACCCG
CCGTCCTCAGCCTGCACCCGGCCACCCTCGGCACCAGTGAACCTGATCTCCAGTGTGAAT
GGGACATCAGTGACTCTGGAGTGGGCCCCTCCCCTGGACCCAGGTGGCCGCAGTGACATC
ACCTACAATGCCGTGTGCCGCCGCTGCCCCTGGGCACTGAGCCGCTGCGAGGCATGTGGG
AGCGGCACCCGCTTTGTGCCCCAGCAGACAAGCCTGGTGCAGGCCAGCCTGCTGGTGGCC
AACCTGCTGGCCCACATGAACTACTCCTTCTGGATCGAGGCCGTCAATGGCGTGTCCGAC
CTGAGCCCCGAGCCCCGCCGGGCCGCTGTGGTCAACATCACCACGAACCAGGCAGGTAGG
CGGAGAAACTCCGTCCCGCAGCGTCCTGGTCCCCCAGCTTCCCCTGCCTCAGACCCATCC
AGGGATCAGAGCTCTGCCGGGGACGTGCTGTGGGCCTTTAGGCAAGTGCCTCTCTGGCCC
TGCGCTCCTCACCAGGACCCAGAGCTGGAGGCTCTTCATTGCCTTTAG
|
| Protein Properties |
| Number of Residues
| 495 |
| Molecular Weight
| 53899.3 |
| Theoretical pI
| 6.79 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>EPH receptor A8
MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
LSPEPRRAAVVNITTNQAGRRRNSVPQRPGPPASPASDPSRDQSSAGDVLWAFRQVPLWP
CAPHQDPELEALHCL
|
| External Links |
| GenBank ID Protein
| 56417854 |
| UniProtKB/Swiss-Prot ID
| P29322 |
| UniProtKB/Swiss-Prot Entry Name
| Q8IUX6_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AL035703 |
| GeneCard ID
| EPHA8 |
| GenAtlas ID
| EPHA8 |
| HGNC ID
| HGNC:3391 |
| References |
| General References
| Not Available |