Cannabis Compound Database: Showing Protein Ubiquitin-like modifier-activating enzyme 7 (CDBP04445)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP04445

Secondary Accession Numbers

Not Available

Name

Ubiquitin-like modifier-activating enzyme 7

Description

Not Available

Synonyms

D8
Ubiquitin-activating enzyme 7
Ubiquitin-activating enzyme E1 homolog

Gene Name

UBA7

Protein Type

Enzyme

Biological Properties

General Function

Involved in catalytic activity

Specific Function

Activates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin- E1 thioester and free AMP

GO Classification

Function
binding
catalytic activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
small protein activating enzyme activity
Process
metabolic process
macromolecule metabolic process
macromolecule modification
protein modification process

Cellular Location

Not Available

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:3

Locus

3p21

SNPs

UBA7

Gene Sequence

>3039 bp
ATGGATGCCCTGGACGCTTCGAAGCTACTGGATGAGGAGCTGTATTCAAGACAGCTGTAT
GTGCTGGGCTCACCTGCCATGCAGAGGATTCAGGGAGCCAGGGTCCTGGTGTCAGGCCTG
CAGGGCCTGGGGGCCGAGGTGGCCAAGAACTTGGTTCTGATGGGTGTGGGCAGCCTCACT
CTGCATGATCCCCACCCCACCTGCTGGTCCGACCTGGCTGCCCAGTTTCTCCTCTCAGAG
CAGGACTTGGAAAGGAGCAGAGCCGAGGCCTCTCAAGAGCTCTTGGCTCAGCTCAACAGA
GCTGTCCAGGTCGTCGTGCACACGGGTGACATCACTGAGGACCTGCTGTTGGACTTCCAG
GTGGTGGTGCTGACTGCTGCAAAGCTGGAGGAGCAGCTGAAGGTGGGCACCTTGTGTCAT
AAGCATGGAGTTTGCTTTCTGGCGGCTGACACCCGGGGCCTCGTGGGGCAGTTGTTCTGT
GACTTTGGTGAGGACTTCACTGTGCAGGACCCCACAGAGGCAGAACCCCTGACAGCTGCC
ATCCAGCACATCTCCCAGGGCTCCCCTGGCATTCTCACTCTGAGGAAAGGGGCCAATACC
CACTACTTCCGTGATGGAGACTTGGTGACTTTCTCGGGAATTGAGGGAATGGTTGAGCTC
AACGACTGTGATCCCCGGTCTATCCACGTGCGGGAGGATGGGTCCCTGGAGATTGGAGAC
ACAACAACTTTCTCTCGGTACTTGCGTGGTGGGGCTATCACTGAAGTCAAGAGACCCAAG
ACTGTGAGACATAAGTCCCTGGACACAGCCCTGCTCCAGCCCCATGTGGTGGCCCAGAGC
TCCCAGGAAGTTCACCATGCCCACTGCCTGCATCAGGCCTTCTGTGCACTGCACAAGTTC
CAGCACCTCCATGGCCGGCCACCCCAGCCCTGGGATCCTGTTGATGCAGAGACTGTGGTG
GGCCTGGCCCGGGACCTGGAACCACTGAAGCGGACAGAGGAAGAGCCACTGGAAGAGCCA
CTGGATGAGGCCCTAGTGCGGACAGTCGCCCTAAGCAGTGCAGGTGTCTTGAGCCCTATG
GTGGCCATGCTGGGTGCAGTAGCTGCCCAGGAAGTGCTGAAGGCAATCTCCAGGAAGTTC
ATGCCTCTGGACCAGTGGCTTTACTTTGATGCCCTCGATTGTCTTCCGGAAGATGGGGAG
CTCCTTCCCAGTCCTGAGGACTGTGCCCTGAGAGGCAGCCGCTATGATGGGCAAATTGCA
GTGTTTGGGGCTGGTTTTCAGGAGAAACTGAGACGCCAGCACTACCTCCTGGTGGGCGCT
GGTGCCATTGGTTGTGAGCTGCTCAAAGTCTTTGCCCTAGTGGGACTGGGGGCCGGGAAC
AGCGGGGGCTTGACTGTTGTTGACATGGACCACATAGAGCGCTCCAATCTCAGCCGTCAG
TTCCTCTTCAGGTCCCAGGACGTTGGTAGACCCAAGGCAGAGGTGGCTGCAGCAGCTGCC
CGGGGCCTGAACCCAGACTTACAGGTGATCCCGCTCACCTACCCACTGGATCCCACCACA
GAGCACATCTATGGGGATAACTTTTTCTCCCGTGTGGATGGTGTGGCTGCTGCCCTGGAC
AGTTTCCAGGCCCGGCGCTATGTGGCTGCTCGTTGCACCCACTATCTGAAGCCACTGCTG
GAGGCAGGCACATCGGGCACCTGGGGCAGTGCTACAGTATTCATGCCACATGTGACTGAG
GCCTACAGAGCCCCTGCCTCAGCTGCAGCTTCTGAGGATGCCCCCTACCCTGTCTGTACC
GTGCGGTACTTCCCTAGCACAGCCGAGCACACCCTGCAGTGGGCCCGGCATGAGTTTGAA
GAACTCTTCCGACTGTCTGCAGAGACCATCAACCACCACCAACAGGCACACACTTCCCTG
GCAGACATGGATGAGCCACAGACACTCACCTTACTGAAGCCAGTGCTTGGGGTCCTGAGA
GTGCGTCCACAGAACTGGCAAGACTGTGTGGCGTGGGCTCTTGGCCACTGGAAACTCTGC
TTTCATTATGGCATCAAACAGCTGCTGAGGCACTTCCCACCTAATAAAGTGCTTGAGGAT
GGAACTCCCTTCTGGTCAGGTCCCAAACAGTGTCCCCAGCCCTTGGAGTTTGACACCAAC
CAAGACACACACCTCCTCTACGTACTGGCAGCTGCCAACCTGTATGCCCAGATGCATGGG
CTGCCTGGCTCACAGGACTGGACTGCACTCAGGGAGCTGCTGAAGCTGCTGCCACAGCCT
GACCCCCAACAGATGGCCCCCATCTTTGCTAGTAATCTAGAGCTGGCTTCGGCTTCTGCT
GAGTTTGGCCCTGAGCAGCAGAAGGAACTGAACAAAGCCCTGGAAGTCTGGAGTGTGGGC
CCTCCCCTGAAGCCTCTGATGTTTGAGAAGGATGATGACAGCAACTTCCATGTGGACTTT
GTGGTAGCGGCAGCTAGCCTGAGATGTCAGAACTACGGGATTCCACCGGTCAACCGTGCC
CAGAGCAAGCGAATTGTGGGCCAGATTATCCCAGCCATTGCCACCACTACAGCAGCTGTG
GCAGGCCTGTTGGGCCTGGAGCTGTATAAGGTGGTGAGTGGGCCACGGCCTCGTAGTGCC
TTTCGCCACAGCTACCTACATCTGGCTGAAAACTACCTCATCCGCTATATGCCTTTTGCC
CCAGCCATCCAGACGTTCCATCACCTGAAGTGGACCTCTTGGGACCGTCTGAAGGTACCA
GCTGGGCAGCCTGAGAGGACCCTGGAGTCGCTGCTGGCTCATCTTCAGGAGCAGCACGGG
TTGAGGGTGAGGATCCTGCTGCACGGCTCAGCCCTGCTCTATGCGGCCGGATGGTCACCT
GAAAAGCAGGCCCAGCACCTGCCCCTCAGGGTGACAGAACTGGTTCAGCAGCTGACAGGC
CAGGCACCTGCTCCTGGGCAGCGGGTGTTGGTGCTAGAGCTGAGCTGTGAGGGTGACGAC
GAGGACACTGCCTTCCCACCTCTGCACTATGAGCTGTGA

Protein Properties

Number of Residues

1012

Molecular Weight

111693.3

Theoretical pI

5.96

Pfam Domain Function

ThiF (PF00899 )
UBA_e1_C (PF09358 )
UBA_e1_thiolCys (PF10585 )
UBACT (PF02134 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Ubiquitin-like modifier-activating enzyme 7
MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLT
LHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQ
VVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAA
IQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGD
TTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKF
QHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPM
VAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIA
VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ
FLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALD
SFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCT
VRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLR
VRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTN
QDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASA
EFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRA
QSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFA
PAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSP
EKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL

External Links

GenBank ID Protein

38045948

UniProtKB/Swiss-Prot ID

P41226

UniProtKB/Swiss-Prot Entry Name

UBA7_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_003335.2

GeneCard ID