| Identification |
|---|
| HMDB Protein ID
| CDBP04435 |
| Secondary Accession Numbers
| Not Available |
| Name
| E3 ubiquitin-protein ligase CCNB1IP1 |
| Description
| Not Available |
| Synonyms
|
- Cyclin-B1-interacting protein 1
- Human enhancer of invasion 10
|
| Gene Name
| CCNB1IP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ligase activity |
| Specific Function
| E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
- Chromosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q11.2 |
| SNPs
| CCNB1IP1 |
| Gene Sequence
|
>834 bp
ATGTCTTTGTGTGAAGACATGCTGCTTTGTAATTATCGAAAGTGTCGCATCAAACTCTCT
GGCTATGCATGGGTCACTGCCTGCTCTCACATCTTCTGTGATCAGCATGGCAGTGGTGAG
TTTAGTCGCTCACCAGCTATCTGTCCTGCCTGCAACAGTACCCTTTCTGGAAAGCTAGAT
ATTGTCCGCACAGAACTCAGTCCATCAGAGGAATATAAAGCTATGGTATTGGCAGGACTG
CGACCAGAGATCGTGTTGGACATTAGCTCCCGAGCGCTGGCCTTCTGGACATATCAGGTA
CATCAGGAACGTCTCTATCAAGAATACAATTTCAGCAAGGCTGAGGGCCATCTGAAACAG
ATGGAGAAGATATATACTCAGCAAATACAAAGCAAGGATGTAGAATTGACCTCTATGAAA
GGGGAGGTTACCTCCATGAAGAAAGTACTAGAAGAATACAAGAAAAAGTTCAGTGACATC
TCTGAGAAACTTATGGAGCGCAATCGTCAGTATCAAAAGCTCCAAGGCCTCTATGATAGC
CTTAGGCTACGAAACATCACTATTGCTAACCATGAAGGCACCCTTGAACCATCCATGATT
GCACAGTCTGGTGTTCTTGGCTTCCCATTAGGTAACAACTCCAAGTTTCCTTTGGATAAT
ACACCTGTTCGAAATCGGGGCGATGGAGATGGAGATTTTCAGTTCAGACCATTTTTTGCG
GGTTCTCCCACAGCACCTGAACCCAGCAACAGCTTTTTTAGTTTTGTCTCTCCAAGTCGT
GAATTAGAGCAGCAGCAAGTTTCTAGCAGGGCCTTCAAAGTAAAAAGAATTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 277 |
| Molecular Weight
| 31543.7 |
| Theoretical pI
| 8.46 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>E3 ubiquitin-protein ligase CCNB1IP1
MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLD
IVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQ
MEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDS
LRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFA
GSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI
|
| External Links |
|---|
| GenBank ID Protein
| 7107350 |
| UniProtKB/Swiss-Prot ID
| Q9NPC3 |
| UniProtKB/Swiss-Prot Entry Name
| CIP1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF216381 |
| GeneCard ID
| CCNB1IP1 |
| GenAtlas ID
| CCNB1IP1 |
| HGNC ID
| HGNC:19437 |
| References |
|---|
| General References
| Not Available |