Showing Protein UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 (CDBP04377)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP04377
Secondary Accession Numbers Not Available
Name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
Description Not Available
Synonyms
  1. BGnT-8
  2. Beta-1,3-Gn-T8
  3. Beta-1,3-N-acetylglucosaminyltransferase 8
  4. Beta3Gn-T8
Gene Name B3GNT8
Protein Type Enzyme
Biological Properties
General Function Involved in galactosyltransferase activity
Specific Function Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans
GO Classification
Component
membrane
cell part
Function
galactosyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring hexosyl groups
transferase activity, transferring glycosyl groups
Process
macromolecule metabolic process
macromolecule modification
protein modification process
protein amino acid glycosylation
metabolic process
Cellular Location
  1. Golgi apparatus membrane
  2. Single-pass type II membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.2
SNPs B3GNT8
Gene Sequence 
>1194 bp
ATGCGCTGCCCCAAGTGCCTTCTCTGCCTGTCAGCACTGCTCACACTCCTGGGCCTCAAA
GTGTACATCGAGTGGACATCCGAGTCCCGGCTCAGCAAGGCCTACCCCAGCCCTCGGGGC
ACCCCGCCAAGCCCCACGCCAGCCAACCCTGAGCCCACCCTACCTGCCAACCTCTCCACC
CGCCTGGGCCAGACTATCCCGCTGCCCTTTGCTTACTGGAACCAGCAGCAGTGGCGGCTG
GGGTCCCTGCCCAGTGGGGACAGCACTGAAACGGGGGGCTGCCAGGCTTGGGGGGCCGCC
GCCGCCACCGAGATCCCTGACTTCGCCTCCTACCCCAAGGACCTCCGCCGCTTCTTGCTG
TCAGCAGCCTGCCGGAGCTTCCCACAGTGGCTGCCTGGAGGTGGTGGCAGCCAAGTCTCC
AGCTGCTCAGATACTGATGTCCCCTACCTGCTGTTGGCCGTCAAGTCAGAACCAGGGCGC
TTTGCAGAACGACAGGCCGTGAGAGAGACGTGGGGCAGTCCAGCTCCAGGGATCCGGCTG
CTCTTCCTGCTAGGGTCTCCGGTGGGTGAGGCGGGGCCTGACCTAGACTCACTAGTGGCC
TGGGAGAGCCGTCGCTACAGTGACCTGCTGCTCTGGGACTTCCTCGACGTCCCATTCAAC
CAGACGCTCAAAGACCTGCTGCTGCTGGCCTGGCTGGGCCGCCACTGCCCCACCGTGAGT
TTTGTCTTGCGAGCTCAGGACGATGCCTTTGTACACACCCCTGCCCTGCTGGCTCACCTG
CGGGCCCTGCCACCTGCCTCGGCCCGAAGCCTCTACCTGGGTGAGGTCTTTACCCAGGCC
ATGCCTCTCCGGAAGCCAGGAGGACCCTTCTATGTGCCCGAGTCCTTCTTCGAAGGTGGC
TACCCAGCCTATGCAAGCGGGGGTGGCTACGTCATTGCCGGGCGCCTGGCACCCTGGCTG
CTGCGGGCGGCAGCCCGTGTGGCACCCTTCCCCTTTGAGGACGTCTACACTGGCCTTTGC
ATCCGAGCCCTGGGCCTGGTGCCCCAGGCCCACCCAGGCTTCCTCACAGCCTGGCCAGCA
GACCGCACTGCGGACCACTGTGCTTTCCGCAACCTGCTGCTGGTACGGCCCCTGGGCCCC
CAGGCCAGCATTCGGCTCTGGAAACAACTGCAAGACCCAAGGCTCCAGTGCTGA
Protein Properties
Number of Residues 397
Molecular Weight 43395.4
Theoretical pI 8.4
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["7-23"]
Protein Sequence 
>UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPTLPANLST
RLGQTIPLPFAYWNQQQWRLGSLPSGDSTETGGCQAWGAAAATEIPDFASYPKDLRRFLL
SAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWGSPAPGIRL
LFLLGSPVGEAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVS
FVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEGG
YPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYTGLCIRALGLVPQAHPGFLTAWPA
DRTADHCAFRNLLLVRPLGPQASIRLWKQLQDPRLQC
GenBank ID Protein 57207880
UniProtKB/Swiss-Prot ID Q7Z7M8
UniProtKB/Swiss-Prot Entry Name B3GN8_HUMAN
PDB IDs Not Available
GenBank Gene ID AB175895
GeneCard ID B3GNT8
GenAtlas ID B3GNT8
HGNC ID HGNC:24139
References
General References Not Available