| Identification |
|---|
| HMDB Protein ID
| CDBP04372 |
| Secondary Accession Numbers
| Not Available |
| Name
| Dehydrodolichyl diphosphate synthase |
| Description
| Not Available |
| Synonyms
|
- Dedol-PP synthase
- Cis-isoprenyltransferase
- Epididymis tissue protein Li 189m
- CIT
- Cis-IPTase
|
| Gene Name
| DHDDS |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transferase activity, transferring alkyl or aryl (other than methyl) groups |
| Specific Function
| Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein.
|
| GO Classification
|
| Biological Process |
| protein glycosylation |
| Cellular Component |
| endoplasmic reticulum membrane |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring alkyl or aryl (other than methyl) groups |
| Molecular Function |
| transferase activity, transferring alkyl or aryl (other than methyl) groups |
| Process |
| physiological process |
| metabolism |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | protein glycosylation | Not Available | Not Available | | Terpenoid backbone biosynthesis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| DHDDS |
| Gene Sequence
|
>1002 bp
ATGTCATGGATCAAGGAAGGAGAGCTGTCACTTTGGGAGCGGTTCTGTGCCAACATCATA
AAGGCAGGCCCAATGCCGAAACACATTGCATTCATAATGGACGGGAACCGTCGCTATGCC
AAGAAGTGCCAGGTGGAGCGGCAGGAAGGCCACTCACAGGGCTTCAACAAGCTAGCTGAG
ACTCTGCGGTGGTGTTTGAACCTGGGCATCCTAGAGGTGACAGTCTACGCATTCAGCATT
GAGAACTTCAAACGCTCCAAGAGTGAGGTAGACGGGCTTATGGATCTGGCCCGGCAGAAG
TTCAGCCGCTTGATGGAAGAAAAGGAGAAACTGCAGAAGCATGGGGTGTGTATCCGGGTC
CTGGGCGATCTGCACTTGTTGCCCTTGGATCTCCAGGAGCTGATTGCACAAGCTGTACAG
GCCACGAAGAACTACAACAAGTGTTTCCTGAATGTCTGTTTTGCATACACATCCCGTCAT
GAGATCAGCAATGCTGTGAGAGAGATGGCCTGGGGGGTGGAGCAAGGCCTGTTGGATCCC
AGTGATATCTCTGAGTCTCTGCTTGATAAGTGCCTCTATACCAACCGCTCTCCTCATCCT
GACATCTTGATACGGACTTCTGGAGAAGTGCGGCTGAGTGACTTCTTGCTATGGCAGACC
TCTCACTCCTGCCTGGTGTTCCAACCCGTTCTGTGGCCAGAGTATACATTTTGGAACCTC
TTCGAGGCCATCCTGCAGTTCCAGATGAACCATAGCGTGCTTCAGAAGGCCCGAGACATG
TATGCAGAGGAGCGGAAGAGGCAGCAGCTGGAGAGGGACCAGGCTACAGTGACAGAGCAG
CTGCTGCGAGAGGGGCTCCAAGCCAGTGGGGACGCCCAGCTCCGAAGGACACGCTTGCAC
AAACTCTCGGCCAGACGGGAAGAGCGAGTCCAAGGCTTCCTGCAGGCCTTGGAACTCAAG
CGAGCTGACTGGCTGGCCCGTCTGGGCACTGCATCAGCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 333 |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Dehydrodolichyl diphosphate synthase
MSWIKEGELSLWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAE
TLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEEKEKLQKHGVCIRV
LGDLHLLPLDLQELIAQAVQATKNYNKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDP
SDISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNL
FEAILQFQMNHSVLQKARDMYAEERKRQQLERDQATVTEQLLREGLQASGDAQLRRTRLH
KLSARREERVQGFLQALELKRADWLARLGTASA
|
| External Links |
|---|
| GenBank ID Protein
| 28557344 |
| UniProtKB/Swiss-Prot ID
| Q86SQ9 |
| UniProtKB/Swiss-Prot Entry Name
| DHDDS_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB090852 |
| GeneCard ID
| DHDDS |
| GenAtlas ID
| DHDDS |
| HGNC ID
| HGNC:20603 |
| References |
|---|
| General References
| Not Available |