Cannabis Compound Database: Showing Protein Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (CDBP04338)

Identification Biological properties Gene properties Protein properties External links References XML Show 0 compounds

Identification

HMDB Protein ID

CDBP04338

Secondary Accession Numbers

Not Available

Name

Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase

Description

Not Available

Synonyms

Asparagine-linked glycosylation protein 6 homolog
Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase
Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase

Gene Name

ALG6

Protein Type

Enzyme

Biological Properties

General Function

Involved in transferase activity, transferring hexosyl groups

Specific Function

Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.

GO Classification

Biological Process
dolichol-linked oligosaccharide biosynthetic process
post-translational protein modification
protein N-linked glycosylation via asparagine
Cellular Component
endoplasmic reticulum membrane
integral to membrane
Component
membrane
cell part
endoplasmic reticulum membrane
organelle membrane
Function
catalytic activity
transferase activity
transferase activity, transferring hexosyl groups
transferase activity, transferring glycosyl groups
Molecular Function
glucosyltransferase activity

Cellular Location

Multi-pass membrane protein (Potential)
Endoplasmic reticulum membrane

Pathways

Name	SMPDB/Pathwhiz	KEGG
protein glycosylation	Not Available	Not Available
N-Glycan biosynthesis	Not Available

Gene Properties

Chromosome Location

Locus

1p31.3

SNPs

ALG6

Gene Sequence

>1524 bp
ATGGAGAAATGGTACTTGATGACAGTAGTGGTTTTAATAGGACTAACAGTACGATGGACA
GTGTCTCTTAATTCTTATTCAGGTGCTGGTAAACCGCCTATGTTTGGTGATTATGAAGCT
CAGAGACACTGGCAAGAAATAACTTTTAATTTACCGGTCAAACAATGGTATTTTAACAGC
AGTGATAACAATTTACAGTATTGGGGATTGGATTACCCACCTCTTACAGCTTATCATAGT
CTCCTATGTGCATATGTGGCAAAGTTTATAAATCCAGACTGGATTGCTCTCCATACATCA
CGTGGATATGAGAGTCAGGCACATAAGCTCTTCATGCGTACAACAGTTTTAATTGCTGAT
CTGCTGATTTACATACCTGCAGTGGTTTTGTACTGTTGTTGCTTAAAAGAAATCTCAACT
AAGAAAAAGATTGCTAATGCATTATGCATCTTGCTGTATCCAGGCCTTATTCTTATAGAC
TATGGACATTTTCAATATAATTCTGTGAGTCTTGGCTTTGCTTTGTGGGGTGTTCTTGGA
ATATCTTGTGACTGCGACCTCCTAGGGTCACTGGCATTTTGCTTAGCTATAAATTATAAA
CAGATGGAACTTTACCACGCCTTGCCATTTTTTTGCTTTTTACTTGGCAAGTGTTTTAAA
AAAGGCCTCAAAGGAAAGGGGTTTGTGTTGCTAGTTAAGCTAGCTTGTATTGTTGTGGCT
TCCTTCGTTCTCTGCTGGCTGCCATTCTTTACAGAAAGGGAACAAACCCTGCAGGTTCTA
AGAAGACTCTTCCCGGTTGATCGTGGATTATTTGAGGATAAAGTAGCCAATATTTGGTGC
AGCTTCAATGTCTTTCTGAAGATTAAGGATATTTTGCCACGTCACATCCAATTAATAATG
AGCTTTTGTTTTACGTTTTTGAGCCTGCTTCCTGCATGCATAAAATTAATACTTCAGCCC
TCTTCCAAAGGATTCAAATTTACACTGGTTAGCTGTGCGCTATCATTCTTTTTATTTTCT
TTCCAAGTACATGAAAAATCCATTCTCTTGGTGTCACTACCAGTCTGCTTAGTTTTAAGT
GAAATTCCTTTTATGTCTACTTGGTTTTTACTTGTGTCAACATTTAGTATGCTACCTCTT
CTATTGAAGGATGAACTCCTAATGCCCTCTGTTGTGACAACAATGGCATTTTTTATAGCT
TGTGTAACTTCCTTTTCAATATTTGAAAAGACTTCTGAAGAAGAACTGCAGTTGAAATCC
TTTTCCATTTCTGTGAGGAAATATCTTCCATGTTTTACATTTCTTTCCAGAATTATACAA
TATTTGTTTCTTATCTCAGTCATCACTATGGTGCTTCTGACGTTGATGACTGTCACACTG
GATCCTCCTCAGAAACTACCGGACTTGTTTTCTGTATTGGTGTGTTTTGTATCTTGCTTG
AACTTCCTGTTCTTCTTGGTATACTTTAACATTATTATTATGTGGGATTCCAAAAGTGGA
AGAAATCAGAAGAAAATCAGCTAG

Protein Properties

Number of Residues

507

Molecular Weight

58119.89

Theoretical pI

8.455

Pfam Domain Function

Alg6_Alg8 (PF03155 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
MEKWYLMTVVVLIGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNS
SDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIALHTSRGYESQAHKLFMRTTVLIAD
LLIYIPAVVLYCCCLKEISTKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLG
ISCDCDLLGSLAFCLAINYKQMELYHALPFFCFLLGKCFKKGLKGKGFVLLVKLACIVVA
SFVLCWLPFFTEREQTLQVLRRLFPVDRGLFEDKVANIWCSFNVFLKIKDILPRHIQLIM
SFCFTFLSLLPACIKLILQPSSKGFKFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLS
EIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTTMAFFIACVTSFSIFEKTSEEELQLKS
FSISVRKYLPCFTFLSRIIQYLFLISVITMVLLTLMTVTLDPPQKLPDLFSVLVCFVSCL
NFLFFLVYFNIIIMWDSKSGRNQKKIS

External Links

GenBank ID Protein

5281124

UniProtKB/Swiss-Prot ID

Q9Y672

UniProtKB/Swiss-Prot Entry Name

ALG6_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF102851

GeneCard ID