| Identification |
|---|
| HMDB Protein ID
| CDBP04327 |
| Secondary Accession Numbers
| Not Available |
| Name
| 14-3-3 protein gamma |
| Description
| Not Available |
| Synonyms
|
- 14-3-3 protein gamma, N-terminally processed
- KCIP-1
- Protein kinase C inhibitor protein 1
|
| Gene Name
| YWHAG |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein domain specific binding |
| Specific Function
| Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner |
| GO Classification
|
| Function |
| binding |
| protein binding |
| protein domain specific binding |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q11.23 |
| SNPs
| YWHAG |
| Gene Sequence
|
>744 bp
ATGGTGGACCGCGAGCAACTGGTGCAGAAAGCCCGGCTGGCCGAGCAGGCGGAGCGCTAC
GACGACATGGCCGCGGCCATGAAGAACGTGACAGAGCTGAATGAGCCACTGTCGAATGAG
GAACGAAACCTTCTGTCTGTGGCCTACAAGAACGTTGTGGGGGCACGCCGCTCTTCCTGG
AGGGTCATCAGTAGCATTGAGCAGAAGACATCTGCAGACGGCAATGAGAAGAAGATTGAG
ATGGTCCGTGCGTACCGGGAGAAGATAGAGAAGGAGTTGGAGGCTGTGTGCCAGGATGTG
CTGAGCCTGCTGGATAACTACCTGATCAAGAATTGCAGCGAGACCCAGTACGAGAGCAAA
GTGTTCTACCTGAAGATGAAAGGGGACTACTACCGCTACCTGGCTGAAGTGGCCACCGGA
GAGAAAAGGGCGACGGTGGTGGAGTCCTCCGAGAAGGCCTACAGCGAAGCCCACGAGATC
AGCAAAGAGCACATGCAGCCCACCCACCCCATCCGATTAGGCCTGGCTCTTAACTACTCC
GTCTTCTACTATGAGATCCAGAACGCCCCAGAGCAAGCGTGCCACTTGGCCAAGACCGCG
TTCGACGACGCCATCGCCGAGCTTGACACCCTCAACGAGGACTCCTACAAGGACTCCACG
CTCATCATGCAGCTCCTCCGCGACAACCTCACGCTCTGGACGAGCGACCAGCAGGACGAC
GATGGCGGCGAAGGCAACAATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 247 |
| Molecular Weight
| 28302.3 |
| Theoretical pI
| 4.52 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>14-3-3 protein gamma
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSW
RVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESK
VFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYS
VFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD
DGGEGNN
|
| External Links |
|---|
| GenBank ID Protein
| 6016838 |
| UniProtKB/Swiss-Prot ID
| P61981 |
| UniProtKB/Swiss-Prot Entry Name
| 1433G_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB024334 |
| GeneCard ID
| YWHAG |
| GenAtlas ID
| YWHAG |
| HGNC ID
| HGNC:12852 |
| References |
|---|
| General References
| Not Available |