| Identification |
|---|
| HMDB Protein ID
| CDBP04326 |
| Secondary Accession Numbers
| Not Available |
| Name
| 14-3-3 protein beta/alpha |
| Description
| Not Available |
| Synonyms
|
- 14-3-3 protein beta/alpha, N-terminally processed
- KCIP-1
- Protein 1054
- Protein kinase C inhibitor protein 1
|
| Gene Name
| YWHAB |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein domain specific binding |
| Specific Function
| Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis |
| GO Classification
|
| Function |
| binding |
| protein binding |
| protein domain specific binding |
|
| Cellular Location
|
- Cytoplasm
- Melanosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20q13.1 |
| SNPs
| YWHAB |
| Gene Sequence
|
>741 bp
ATGACAATGGATAAAAGTGAGCTGGTACAGAAAGCCAAACTCGCTGAGCAGGCTGAGCGA
TATGATGATATGGCTGCAGCCATGAAGGCAGTCACAGAACAGGGGCATGAACTCTCCAAC
GAAGAGAGAAATCTGCTCTCTGTTGCCTACAAGAATGTGGTAGGCGCCCGCCGCTCTTCC
TGGCGTGTCATCTCCAGCATTGAGCAGAAAACAGAGAGGAATGAGAAGAAGCAGCAGATG
GGCAAAGAGTACCGTGAGAAGATAGAGGCAGAACTGCAGGACATCTGCAATGATGTTCTG
GAGCTGTTGGACAAATATCTTATTCCCAATGCTACACAACCAGAAAGTAAGGTGTTCTAC
TTGAAAATGAAAGGAGATTATTTTAGGTATCTTTCTGAAGTGGCATCTGGAGACAACAAA
CAAACCACTGTGTCGAACTCCCAGCAGGCTTACCAGGAAGCATTTGAAATTAGTAAGAAA
GAAATGCAGCCTACACACCCAATTCGTCTTGGTCTGGCACTAAATTTCTCAGTCTTTTAC
TATGAGATTCTAAACTCTCCTGAAAAGGCCTGTAGCCTGGCAAAAACGGCATTTGATGAA
GCAATTGCTGAATTGGATACGCTGAATGAAGAGTCTTATAAAGACAGCACTCTGATCATG
CAGTTACTTAGGGACAATCTCACTCTGTGGACATCGGAAAACCAGGGAGACGAAGGAGAC
GCTGGGGAGGGAGAGAACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 246 |
| Molecular Weight
| 28082.2 |
| Theoretical pI
| 4.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>14-3-3 protein beta/alpha
MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
AGEGEN
|
| External Links |
|---|
| GenBank ID Protein
| 158258871 |
| UniProtKB/Swiss-Prot ID
| P31946 |
| UniProtKB/Swiss-Prot Entry Name
| 1433B_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK292717 |
| GeneCard ID
| YWHAB |
| GenAtlas ID
| YWHAB |
| HGNC ID
| HGNC:12849 |
| References |
|---|
| General References
| Not Available |