Cannabis Compound Database: Showing Protein D-glucuronyl C5-epimerase (CDBP04322)

Identification Biological properties Gene properties Protein properties External links References XML Show 0 compounds

Identification

HMDB Protein ID

CDBP04322

Secondary Accession Numbers

Not Available

Name

D-glucuronyl C5-epimerase

Description

Not Available

Synonyms

Heparin/heparan sulfate:glucuronic acid C5-epimerase

Gene Name

GLCE

Protein Type

Enzyme

Biological Properties

General Function

Involved in racemase and epimerase activity, acting on carbohydrates and derivatives

Specific Function

Converts D-glucuronic acid residues adjacent to N- sulfate sugar residues to L-iduronic acids

GO Classification

Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
catalytic activity
racemase and epimerase activity
racemase and epimerase activity, acting on carbohydrates and derivatives
isomerase activity
Process
polysaccharide metabolic process
metabolic process
primary metabolic process
carbohydrate metabolic process
polysaccharide biosynthetic process
aminoglycan biosynthetic process
glycosaminoglycan biosynthetic process

Cellular Location

Golgi apparatus membrane
Single-pass type II membrane protein

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:1

Locus

15q23

SNPs

GLCE

Gene Sequence

>1854 bp
ATGCGTTGCTTGGCAGCTCGGGTCAACTATAAGACTTTGATTATTATCTGCGCACTCTTC
ACTTTGGTCACAGTACTTTTGTGGAATAAGTGTTCCAGTGACAAAGCAATCCAGTTTCCA
CGGCGTTCGAGTAGTGGCTTCAGAGTGGATGGGTTTGAAAAAAGAGCAGCAGCATCTGAG
AGTAACAACTATATGAACCACGTGGCCAAACAACAGTCTGAGGAAGCATTCCCTCAGGAA
CAGCAGAAAGCACCCCCTGTTGTTGGGGGCTTCAATAGCAATGTGGGAAGTAAGGTGTTA
GGGCTCAAATATGAAGAAATTGACTGTCTCATAAATGATGAACACACAATTAAAGGGAGA
CGAGAGGGGAACGAAGTCTTTCTTCCATTCACTTGGGTTGAGAAATATTTTGATGTTTAT
GGAAAGGTGGTTCAGTATGATGGCTATGATCGGTTTGAATTCTCTCATAGCTATTCCAAA
GTCTATGCACAGAGAGCCCCCTATCACCCCGATGGTGTGTTTATGTCTTTTGAAGGCTAC
AATGTGGAAGTCCGAGACAGAGTCAAGTGCATAAGTGGGGTTGAAGGTGTGCCATTATCT
ACACAATGGGGACCTCAAGGCTATTTCTATCCAATCCAGATTGCACAGTATGGATTAAGT
CATTACAGCAAGAATCTAACTGAGAAACCTCCTCACATAGAGGTATATGAAACAGCAGAA
GACAGAGACAAAAACAAGCCTAATGACTGGACTGTGCCAAAGGGCTGCTTTATGGCGAAT
GTGGCTGATAAGTCTAGATTCACCAATGTCAAACAGTTTATTGCACCAGAAACCAGTGAA
GGTGTATCCTTGCAACTGGGAAACACAAAAGATTTTATTATTTCATTTGACCTCAAGTTC
TTGACAAATGGAAGTGTGTCCGTGGTTCTAGAGACCACAGAAAAGAATCAGCTCTTCACT
ATACATTATGTCTCAAATGCTCAGCTAATTGCTTTTAAAGAAAGAGATATATACTATGGC
ATTGGGCCCAGAACTTCATGGAGCACAGTTACCAGGGACCTGGTCACTGACCTCAGGAAA
GGAGTGGGTCTTTCAAACACAAAAGCTGTCAAGCCAACCAAAATAATGCCCAAGAAGGTG
GTTAGGTTGATTGCAAAAGGTAAGGGATTCCTCGACAACATTACCATCTCTACCACAGCC
CACATGGCTGCATTTTTTGCTGCTAGTGATTGGCTAGTAAGGAACCAGGATGAGAAAGGT
GGCTGGCCAATTATGGTGACCCGTAAGTTAGGGGAAGGGTTCAAGTCTTTAGAGCCAGGA
TGGTATTCTGCCATGGCCCAAGGGCAAGCCATTTCTACATTAGTCAGGGCCTATCTGTTA
ACAAAAGACCATATATTCCTCAATTCAGCTTTAAGGGCAACAGCCCCTTATAAGTTTCTA
TCTGAGCAGCATGGAGTTAAAGCTGTGTTTATGAATAAACATGACTGGTATGAAGAATAT
CCAACCACACCTAGCTCTTTTGTTTTAAATGGCTTTATGTATTCTTTAATTGGGCTGTAT
GACTTAAAAGAAACTGCAGGGGAAAAACTCGGAAAAGAAGCAAGGTCCTTGTATGAGCGT
GGCATGGAATCTCTTAAAGCCATGCTGCCCTTGTATGACACTGGCTCAGGAACCATCTAT
GACCTCCGTCACTTCATGCTTGGCATCGCTCCTAACCTGGCTCGCTGGGACTATCATACC
ACCCACATCAATCAGTTGCAGCTACTCAGTACCATTGATGAGTCCCCAGTCTTCAAAGAA
TTTGTCAAGAGGTGGAAAAGCTACCTTAAAGGCAGCAGGGCAAAGCACAACTAG

Protein Properties

Number of Residues

617

Molecular Weight

70100.5

Theoretical pI

9.32

Pfam Domain Function

C5-epim_C (PF06662 )

Signals

["None"]

Transmembrane Regions

["12-28"]

Protein Sequence

>D-glucuronyl C5-epimerase
MRCLAARVNYKTLIIICALFTLVTVLLWNKCSSDKAIQFPRRSSSGFRVDGFEKRAAASE
SNNYMNHVAKQQSEEAFPQEQQKAPPVVGGFNSNVGSKVLGLKYEEIDCLINDEHTIKGR
REGNEVFLPFTWVEKYFDVYGKVVQYDGYDRFEFSHSYSKVYAQRAPYHPDGVFMSFEGY
NVEVRDRVKCISGVEGVPLSTQWGPQGYFYPIQIAQYGLSHYSKNLTEKPPHIEVYETAE
DRDKNKPNDWTVPKGCFMANVADKSRFTNVKQFIAPETSEGVSLQLGNTKDFIISFDLKF
LTNGSVSVVLETTEKNQLFTIHYVSNAQLIAFKERDIYYGIGPRTSWSTVTRDLVTDLRK
GVGLSNTKAVKPTKIMPKKVVRLIAKGKGFLDNITISTTAHMAAFFAASDWLVRNQDEKG
GWPIMVTRKLGEGFKSLEPGWYSAMAQGQAISTLVRAYLLTKDHIFLNSALRATAPYKFL
SEQHGVKAVFMNKHDWYEEYPTTPSSFVLNGFMYSLIGLYDLKETAGEKLGKEARSLYER
GMESLKAMLPLYDTGSGTIYDLRHFMLGIAPNLARWDYHTTHINQLQLLSTIDESPVFKE
FVKRWKSYLKGSRAKHN

External Links

GenBank ID Protein

51317380

UniProtKB/Swiss-Prot ID

O94923

UniProtKB/Swiss-Prot Entry Name

GLCE_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_015554.1

GeneCard ID