| Identification |
|---|
| HMDB Protein ID
| CDBP04261 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable sodium-coupled neutral amino acid transporter 6 |
| Description
| Not Available |
| Synonyms
|
- N-system amino acid transporter 1
- NAT-1
- Na(+)-coupled neutral amino acid transporter 6
- Solute carrier family 38 member 6
|
| Gene Name
| SLC38A6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Probable sodium-dependent amino acid/proton antiporter |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q23.1 |
| SNPs
| SLC38A6 |
| Gene Sequence
|
>1371 bp
ATGGAGGCGTCCTGGGGGAGCTTCAACGCTGAGCGGGGCTGGTATGTCTCTGTCCAGCAG
CCTGAAGAAGCGGAGGCCGAAGAGTTGAGTCCGTTGCTAAGCAACGAACTTCACAGACAG
CGATCCCCAGGTGTTTCATTTGGTTTATCAGTGTTTAATTTGATGAATGCCATCATGGGA
AGTGGCATCCTTGGCTTAGCTTATGTTATGGCTAATACCGGTGTCTTTGGATTTAGCTTC
TTGCTGCTGACAGTTGCTCTCCTGGCTTCTTACTCAGTCCATCTTCTGCTTAGTATGTGT
ATTCAGACAGCTGTAACATCTTATGAAGATCTTGGACTCTTTGCATTTGGATTACCTGGA
AAGTTGGTGGTGGCAGGCACCATAATAATTCAGAATATTGGAGCTATGTCATCTTATCTT
TTAATTATTAAAACAGAGCTTCCTGCTGCTATTGCAGAATTTTTGACTGGAGACTATAGT
AGATATTGGTATCTTGATGGACAAACACTACTAATAATCATATGTGTTGGCATTGTGTTC
CCTCTTGCACTTCTTCCCAAAATAGGCTTTCTTGGCTACACAAGTAGTTTATCATTTTTC
TTTATGATGTTCTTTGCTCTTGTGGTAATAATTAAAAAATGGTCCATCCCTTGTCCTCTG
ACATTAAATTATGTAGAGAAAGGCTTCCAGATTTCAAATGTTACAGATGATTGTAAGCCA
AAGCTCTTTCATTTCTCCAAAGAGAGTGCTTATGCCTTACCAACCATGGCTTTTTCATTT
CTCTGCCATACCTCAATATTGCCCATATACTGTGAACTTCAAAGTCCTTCAAAGAAAAGA
ATGCAGAATGTTACCAATACAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCA
CTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAAAAGGTTATAGT
AAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTG
CTTTTGACAGTCCCTCTAATCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTC
TCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCACTCAATATTATC
ATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCC
AGTACATCAACATGTTTGATTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGA
GAGGATTTTCTGTCATGGAAAAAGCTTGGGGCATTCGTTTTGCTCATCTTTGGAATTTTG
GTTGGGAATTTTAGTTTAGCACTCATCATTTTTGATTGGATTAATAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 456 |
| Molecular Weight
| 50927.9 |
| Theoretical pI
| 7.98 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["42-62", "85-105", "111-131", "170-190", "191-211", "250-270", "288-308", "327-347", "371-391", "394-414", "431-451"]
|
| Protein Sequence
|
>Probable sodium-coupled neutral amino acid transporter 6
MEASWGSFNAERGWYVSVQQPEEAEAEELSPLLSNELHRQRSPGVSFGLSVFNLMNAIMG
SGILGLAYVLANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDLGLFAFGLPG
KLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVF
PLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKP
KLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISA
LFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFF
SNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSR
EDFLSWKKLGAFVLLIFGILVGNFSLALIIFDWINK
|
| External Links |
|---|
| GenBank ID Protein
| 24181971 |
| UniProtKB/Swiss-Prot ID
| Q8IZM9 |
| UniProtKB/Swiss-Prot Entry Name
| S38A6_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF543422 |
| GeneCard ID
| SLC38A6 |
| GenAtlas ID
| SLC38A6 |
| HGNC ID
| HGNC:19863 |
| References |
|---|
| General References
| Not Available |