| Identification |
|---|
| HMDB Protein ID
| CDBP04254 |
| Secondary Accession Numbers
| Not Available |
| Name
| Sodium/bile acid cotransporter 4 |
| Description
| Not Available |
| Synonyms
|
- Na(+)/bile acid cotransporter 4
- Solute carrier family 10 member 4
|
| Gene Name
| SLC10A4 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in bile acid:sodium symporter activity |
| Specific Function
| Not Available |
| GO Classification
|
| Cellular Component |
| integral to membrane |
| Component |
| membrane |
| cell part |
| Function |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| organic acid:sodium symporter activity |
| transporter activity |
| bile acid:sodium symporter activity |
| organic acid transmembrane transporter activity |
| Molecular Function |
| bile acid:sodium symporter activity |
| Process |
| sodium ion transport |
| establishment of localization |
| transport |
| monovalent inorganic cation transport |
| ion transport |
| cation transport |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| 4p11 |
| SNPs
| SLC10A4 |
| Gene Sequence
|
>1314 bp
ATGGACGGCAACGACAACGTGACCCTGCTCTTCGCCCCTCTGCTGCGGGACAACTACACC
CTGGCGCCCAATGCCAGCAGCCTGGGCCCCGGCACGGACCTCGCCCTCGCCCCTGCCTCC
AGCGCCGGCCCCGGCCCTGGGCTCAGCCTCGGGCCGGGTCCGAGCTTCGGCTTCAGCCCC
GGCCCCACTCCGACCCCGGAGCCCACGACCAGCGGCCTCGCGGGCGGCGCGGCGAGCCAC
GGCCCTTCCCCGTTCCCTCGGCCCTGGGCGCCCCACGCGCTCCCGTTCTGGGACACGCCG
CTGAACCACGGGCTGAACGTGTTCGTGGGCGCCGCCCTGTGCATCACCATGCTGGGCCTG
GGCTGCACGGTGGACGTGAACCACTTCGGGGCGCACGTCCGTCGGCCCGTGGGCGCGCTG
CTGGCAGCGCTCTGCCAGTTCGGCCTCCTGCCGCTGCTGGCCTTCCTGCTGGCCCTCGCC
TTCAAGCTGGACGAGGTGGCCGCCGTGGCGGTGCTCCTGTGTGGCTGCTGTCCCGGCGGC
AATCTCTCCAATCTTATGTCCCTGCTGGTTGACGGCGACATGAACCTCAGCATCATCATG
ACCATCTCCTCCACGCTTCTGGCCCTCGTCTTGATGCCCCTGTGCCTGTGGATCTACAGC
TGGGCTTGGATCAACACCCCTATCGTGCAGTTACTACCCCTAGGGACCGTGACCCTGACT
CTCTGCAGCACTCTCATACCTATCGGGTTGGGCGTCTTCATTCGCTACAAATACAGCCGG
GTGGCTGACTACATTGTGAAGGTTTCCCTGTGGTCTCTGCTAGTGACTCTGGTGGTCCTT
TTCATAATGACCGGCACTATGTTAGGACCTGAACTGCTGGCAAGTATCCCTGCAGCTGTT
TATGTGATAGCAATTTTTATGCCTTTGGCAGGCTACGCTTCAGGTTATGGTTTAGCTACT
CTCTTCCATCTTCCACCCAACTGCAAGAGGACTGTATGTCTGGAAACAGGTAGTCAGAAT
GTGCAGCTCTGTACAGCCATTCTAAAACTGGCCTTTCCACCGCAATTCATAGGAAGCATG
TACATGTTTCCTTTGCTGTATGCACTTTTCCAGTCTGCAGAAGCGGGGATTTTTGTTTTA
ATCTATAAAATGTATGGAAGTGAAATGTTGCACAAGCGAGATCCTCTAGATGAAGATGAA
GATACAGATATTTCTTATAAAAAACTAAAAGAAGAGGAAATGGCAGACACTTCCTATGGC
ACAGTGAAAGCAGAAAATATAATAATGATGGAAACCGCTCAGACTTCTCTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 437 |
| Molecular Weight
| 46503.19 |
| Theoretical pI
| 5.277 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Sodium/bile acid cotransporter 4
MDGNDNVTLLFAPLLRDNYTLAPNASSLGPGTDLALAPASSAGPGPGLSLGPGPSFGFSP
GPTPTPEPTTSGLAGGAASHGPSPFPRPWAPHALPFWDTPLNHGLNVFVGAALCITMLGL
GCTVDVNHFGAHVRRPVGALLAALCQFGLLPLLAFLLALAFKLDEVAAVAVLLCGCCPGG
NLSNLMSLLVDGDMNLSIIMTISSTLLALVLMPLCLWIYSWAWINTPIVQLLPLGTVTLT
LCSTLIPIGLGVFIRYKYSRVADYIVKVSLWSLLVTLVVLFIMTGTMLGPELLASIPAAV
YVIAIFMPLAGYASGYGLATLFHLPPNCKRTVCLETGSQNVQLCTAILKLAFPPQFIGSM
YMFPLLYALFQSAEAGIFVLIYKMYGSEMLHKRDPLDEDEDTDISYKKLKEEEMADTSYG
TVKAENIIMMETAQTSL
|
| External Links |
|---|
| GenBank ID Protein
| 56790800 |
| UniProtKB/Swiss-Prot ID
| Q96EP9 |
| UniProtKB/Swiss-Prot Entry Name
| NTCP4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY704414 |
| GeneCard ID
| SLC10A4 |
| GenAtlas ID
| SLC10A4 |
| HGNC ID
| HGNC:22980 |
| References |
|---|
| General References
| Not Available |