| Identification |
|---|
| HMDB Protein ID
| CDBP04250 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cyclin-D1-binding protein 1 |
| Description
| Not Available |
| Synonyms
|
- Grap2 and cyclin-D-interacting protein
- Human homolog of Maid
|
| Gene Name
| CCNDBP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 15q14-q15 |
| SNPs
| CCNDBP1 |
| Gene Sequence
|
>1083 bp
ATGGCGAGCGCAACTGCACCTGCAGCCGCAGTCCCCACCCTGGCTTCGCCTTTGGAGCAG
CTCCGGCACTTGGCGGAGGAGCTGCGGTTGCTCCTGCCTCGAGTGCGGGTCGGCGAAGCC
CAGGAGACCACCGAGGAGTTTAATCGAGAGATGTTCTGGAGAAGACTCAATGAGGCAGCT
GTGACTGTGTCAAGGGAAGCCACGACTCTGACCATAGTCTTCTCTCAGCTTCCACTGCCG
TCTCCACAGGAAACCCAGAAGTTCTGTGAACAAGTCCATGCTGCCATCAAGGCATTTATT
GCAGTGTACTATTTGCTTCCAAAGGATCAGGGGATCACCCTGAGAAAGCTGGTACGGGGC
GCCACCCTGGACATCGTGGATGGCATGGCTCAGCTCATGGAAGTACTTTCCGTCACTCCA
ACTCAGAGCCCTGAGAACAATGACCTTATTTCCTACAACAGTGTCTGGGTTGCGTGCCAG
CAGATGCCTCAGATACCAAGAGATAACAAAGCTGCAGCTCTTTTGATGCTGACCAAGAAT
GTGGATTTTGTGAAGGATGCACATGAAGAAATGGAGCAGGCTGTGGAAGAATGTGACCCT
TACTCTGGCCTCTTGAATGATACTGAGGAGAACAACTCTGACAACCACAATCATGAGGAT
GATGTGTTGGGGTTTCCCAGCAATCAGGACTTGTATTGGTCAGAGGACGATCAAGAGCTC
ATAATCCCATGCCTTGCGCTGGTGAGAGCATCCAAAGCCTGCCTGAAGAAAATTCGGATG
TTAGTGGCAGAGAATGGGAAGAAGGATCAGGTGGCACAGCTGGATGACATTGTGGATATT
TCTGATGAAATCAGCCCTAGTGTGGATGATTTGGCTCTGAGCATATATCCACCTATGTGT
CACCTGACCGTGCGAATCAATTCTGCGAAACTTGTATCTGTTTTAAAGAAGGCACTTGAA
ATTACAAAAGCAAGTCATGTGACCCCTCAGCCAGAAGATAGTTGGATCCCTTTACTTATT
AATGCCATTGATCATTGCATGAATAGAATCAAGGAGCTCACTCAGAGTGAACTTGAATTA
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 360 |
| Molecular Weight
| 40261.5 |
| Theoretical pI
| 4.45 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Cyclin-D1-binding protein 1
MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAA
VTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRG
ATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKN
VDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQEL
IIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMC
HLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
|
| External Links |
|---|
| GenBank ID Protein
| 227500367 |
| UniProtKB/Swiss-Prot ID
| O95273 |
| UniProtKB/Swiss-Prot Entry Name
| CCDB1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_012142.3 |
| GeneCard ID
| CCNDBP1 |
| GenAtlas ID
| CCNDBP1 |
| HGNC ID
| HGNC:1587 |
| References |
|---|
| General References
| Not Available |