| Identification |
|---|
| HMDB Protein ID
| CDBP04243 |
| Secondary Accession Numbers
| Not Available |
| Name
| tRNA wybutosine-synthesizing protein 3 homolog |
| Description
| Not Available |
| Synonyms
|
- tRNA-yW-synthesizing protein 3
|
| Gene Name
| TYW3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in methyltransferase activity |
| Specific Function
| Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1p31.1 |
| SNPs
| TYW3 |
| Gene Sequence
|
>780 bp
ATGGATCGCAGCGCGGAGTTCAGGAAATGGAAGGCGCAATGTTTGAGCAAAGCGGACCTC
AGCCGGAAGGGCAGTGTTGACGAGGATGTGGTAGAGCTTGTGCAGTTTCTGAACATGCGA
GATCAGTTTTTCACCACCAGCTCCTGCGCTGGCCGCATCCTACTCCTTGACCGGGGTATA
AATGGTTTTGAGGTTCAGAAACAAAACTGTTGCTGGCTACTGGTTACACACAAACTTTGT
GTAAAAGATGATGTGATTGTAGCTCTGAAGAAAGCAAATGGTGATGCCACTTTGAAATTT
GAACCATTTGTTCTTCATGTGCAGTGTCGACAATTGCAGGATGCACAGATTCTGCATTCC
ATGGCAATAGATTCTGGTTTCAGGAACTCTGGCATAACGGTGGGAAAGAGAGGAAAAACT
ATGTTGGCTGTCCGGAGTACACATGGCTTAGAAGTTCCATTAAGCCATAAGGGAAAACTG
ATGGTGACAGAGGAATATATTGACTTCCTGTTAAATGTGGCAAATCAAAAAATGGAGGAA
AACAAGAAAAGAATTGAGAGGTTTTACAACTGCCTACAGCATGCTTTGGAAAGGGAAACG
ATGACTAACTTACATCCCAAGATCAAAGAGAAAAATAACTCATCATATATTCATAAGAAA
AAAAGAAACCCAGAAAAAACACGTGCCCAGTGTATTACTAAAGAAAGTGATGAAGAACTT
GAAAATGATGATGATGATGATCTAGGAATCAATGTTACCATCTTCCCTGAAGATTACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 259 |
| Molecular Weight
| 29793.9 |
| Theoretical pI
| 7.77 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>tRNA wybutosine-synthesizing protein 3 homolog
MDRSAEFRKWKAQCLSKADLSRKGSVDEDVVELVQFLNMRDQFFTTSSCAGRILLLDRGI
NGFEVQKQNCCWLLVTHKLCVKDDVIVALKKANGDATLKFEPFVLHVQCRQLQDAQILHS
MAIDSGFRNSGITVGKRGKTMLAVRSTHGLEVPLSHKGKLMVTEEYIDFLLNVANQKMEE
NKKRIERFYNCLQHALERETMTNLHPKIKEKNNSSYIHKKKRNPEKTRAQCITKESDEEL
ENDDDDDLGINVTIFPEDY
|
| External Links |
|---|
| GenBank ID Protein
| 42734381 |
| UniProtKB/Swiss-Prot ID
| Q6IPR3 |
| UniProtKB/Swiss-Prot Entry Name
| TYW3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_138467.2 |
| GeneCard ID
| TYW3 |
| GenAtlas ID
| TYW3 |
| HGNC ID
| HGNC:24757 |
| References |
|---|
| General References
| Not Available |