| Identification |
|---|
| HMDB Protein ID
| CDBP04236 |
| Secondary Accession Numbers
| Not Available |
| Name
| tRNA:m(4)X modification enzyme TRM13 homolog |
| Description
| Not Available |
| Synonyms
|
- Coiled-coil domain-containing protein 76
- tRNA [Gm4] methyltransferase
|
| Gene Name
| TRMT13 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in methyltransferase activity |
| Specific Function
| tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His) (By similarity).
|
| GO Classification
|
| Biological Process |
| tRNA processing |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring one-carbon groups |
| methyltransferase activity |
| Molecular Function |
| metal ion binding |
| methyltransferase activity |
| Process |
| cellular macromolecule metabolic process |
| rna metabolic process |
| ncrna metabolic process |
| trna metabolic process |
| trna processing |
| metabolic process |
| macromolecule metabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| 1p21.2 |
| SNPs
| CCDC76 |
| Gene Sequence
|
>1446 bp
ATGGCGACCTCCGCGACGTCGCCGCACGCGCCTGGTTTTCCAGCTGAGGGTAGATGCGGT
TACTATGTGGAAAAGAAGAAACGGTTCTGCAGGATGGTGGTGGCCGCAGGGAAAAGATTT
TGTGGTGAACACGCTGGAGCCGCGGAGGAAGAAGATGCTCGGAAAAGAATCCTGTGTCCT
TTAGATCCAAAACACACAGTATATGAAGATCAACTAGCAAAGCATTTGAAAAAATGTAAC
TCAAGAGAGAAACCAAAACCTGATTTCTATATTCAAGATATTAATGCAGGCTTAAGAGAT
GAAACAGAAATACCTGAACAATTAGTTCCAATTTCTTCTCTATCTGAAGAGCAGTTGGAA
AAGTTAATTAAGAAATTGAGAAAAGCAAGTGAAGGCTTGAATTCTACACTTAAAGATCAT
ATTATGTCCCATCCAGCATTACACGATGCACTTAATGACCCTAAAAATGGCGATTCTGCA
ACCAAGCACCTGAAACAGCAGGCTTCTATTTTAGGTAACATTGAAAATTTAAAGTTACTT
GGTCCAAGAAGATGCTTTGTTGAGTTTGGAGCGGGAAAGGGAAAATTATCTCATTGGGTT
GATATTGCCTTAAAAGATGCTGAAAAAGTTCACTTCATCCTAGTGGAAAAGGTGACCACA
AGATTCAAGGTGGATGGAAAACACAGAAAGAAAAATTCAGTGTTTGAAAGACTTCAAATT
GATATTCAACACTTGTGTTTGAACAAGATTCCTGTGCTAAGAGAAGAAAAACTACCTGTG
GTAGGAATTGGAAAGCATCTGTGTGGTATGGCAACAGATCTTGCATTACGATGTTTGGTT
GAAACCTATGCTGCCAGTTTTGAGGAAAGGAATGAAGAACCTTTAGCCAAACGCATAAAG
AATGATAAAACAGAAAAAGAAATTTACACTTTGGCCAAGGAAGGAAATGAAAAAAATGTC
CCAGAGAAGTGGAACCCTGTGGCTGGCATTGTTATTGCACTCTGTTGTCACCACAGGTGT
GATTGGAGACATTATGTGGGCAAAGAATATTTCAGGGCTCTAGGCCTTGGAGCAGTGGAA
TTCCATTATTTCCAGCGAATGAGTAGTTGGGCAACTTGTGGGATGCGGAAAACATCTTTG
GAAACCTCAAATAGTACCACAAAGAGGCAAGATAATCAGAATGATGATAGTGAAGAGCAT
GATGATGGAGGATACAGAATCACAGATGATGGCGCTGATTGTTTGCCTGGGCTTCTTAGT
GTTGAAGAAAAGAAGAAAATAGGGCATCTTTGTAAATTGCTGATTGACCAAGGTCGAATC
CAGTATTTGCAGCAGAAGGGATTCAGTCCTGCTTTGCAGTACTATACAGACCCTCTGGTG
TCTTTGGAAAATGTTTTGTTAACTGCTTTACCAAATCATTCTTCATCACCAGAAACAACT
GCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 481 |
| Molecular Weight
| 54246.57 |
| Theoretical pI
| 8.093 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>tRNA guanosine-2'-O-methyltransferase TRM13 homolog
MATSATSPHAPGFPAEGRCGYYVEKKKRFCRMVVAAGKRFCGEHAGAAEEEDARKRILCP
LDPKHTVYEDQLAKHLKKCNSREKPKPDFYIQDINAGLRDETEIPEQLVPISSLSEEQLE
KLIKKLRKASEGLNSTLKDHIMSHPALHDALNDPKNGDSATKHLKQQASILGNIENLKLL
GPRRCFVEFGAGKGKLSHWVDIALKDAEKVHFILVEKVTTRFKVDGKHRKKNSVFERLQI
DIQHLCLNKIPVLREEKLPVVGIGKHLCGMATDLALRCLVETYAASFEERNEEPLAKRIK
NDKTEKEIYTLAKEGNEKNVPEKWNPVAGIVIALCCHHRCDWRHYVGKEYFRALGLGAVE
FHYFQRMSSWATCGMRKTSLETSNSTTKRQDNQNDDSEEHDDGGYRITDDGADCLPGLLS
VEEKKKIGHLCKLLIDQGRIQYLQQKGFSPALQYYTDPLVSLENVLLTALPNHSSSPETT
A
|
| External Links |
|---|
| GenBank ID Protein
| 226493203 |
| UniProtKB/Swiss-Prot ID
| Q9NUP7 |
| UniProtKB/Swiss-Prot Entry Name
| TRM13_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_019083.2 |
| GeneCard ID
| CCDC76 |
| GenAtlas ID
| CCDC76 |
| HGNC ID
| HGNC:25502 |
| References |
|---|
| General References
| Not Available |