| Identification |
|---|
| HMDB Protein ID
| CDBP04235 |
| Secondary Accession Numbers
| Not Available |
| Name
| tRNA guanosine-2'-O-methyltransferase TRM11 homolog |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| TRMT11 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in nucleic acid binding |
| Specific Function
| Catalytic subunit of an S-adenosyl-L-methionine- dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs |
| GO Classification
|
| Function |
| binding |
| catalytic activity |
| transferase activity |
| nucleic acid binding |
| transferase activity, transferring one-carbon groups |
| methyltransferase activity |
| Process |
| methylation |
| metabolic process |
| cellular metabolic process |
| one-carbon metabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:6 |
| Locus
| 6q11.1-q22.33 |
| SNPs
| TRMT11 |
| Gene Sequence
|
>1392 bp
ATGGCGCTGTCGTGTACCCTTAACAGGTATCTGCTCCTCATGGCGCAGGAGCATCTGGAG
TTCCGCCTGCCGGAAATAAAGTCTTTGCTTTTGCTTTTTGGAGGTCAGTTTGCCAGCAGT
CAAGAAACTTATGGAAAGTCACCATTTTGGATTCTTAGCATTCCCTCTGAAGATATTGCA
AGAAATTTGATGAAACGGACAGTGTGTGCCAAGTCTATATTTGAACTATGGGGTCATGGA
CAATCTCCTGAGGAGCTGTACAGTTCTCTTAAAAACTACCCTGTGGAGAAGATGGTTCCA
TTTCTACATTCGGACTCTACATATAAAATAAAGATTCACACTTTTAATAAGACATTGACA
CAAGAAGAGAAAATCAAGCGAATAGATGCACTTGAATTTCTGCCATTTGAAGGAAAAGTG
AATTTAAAGAAACCGCAACATGTATTTTCTGTTTTGGAGGATTATGGTTTAGACCCAAAC
TGCATCCCTGAGAATCCACATAATATTTATTTTGGTAGATGGATTGCAGATGGACAGAGA
GAGCTTATTGAGTCATACAGTGTCAAAAAGAGACACTTTATTGGAAATACAAGTATGGAT
GCTGGTTTGTCATTCATTATGGCTAACCATGGAAAAGTGAAAGAAAATGATATTGTCTTT
GATCCATTTGTTGGAACAGGTGGCCTGCTGATAGCATGTGCTCATTTTGGTGCATATGTG
TATGGGACAGACATAGACTACAACACAGTTCATGGCTTGGGAAAGGCTACTAGGAAAAAC
CAGAAGTGGAGAGGACCAGATGAAAACATTAGGGCCAATCTTCGTCAATATGGTTTAGAG
AAGTATTACCTTGATGTCCTGGTTTCAGATGCATCTAAACCTTCCTGGAGGAAGGGCACA
TATTTTGATGCAATCATTACTGATCCTCCATATGGTATCAGAGAATCTACAAGAAGAACA
GGTTCACAGAAGGAGATACCAAAGGGGATAGAAAAATGGGAAAAATGTCCAGAAAGCCAT
GTTCCTGTTTCCTTGAGTTATCATCTGAGTGATATGTTTCTTGACCTGTTAAACTTCGCA
GCTGAGACCCTCGTTTTAGGTGGAAGACTAGTCTATTGGTTACCGGTGTATACGCCAGAA
TACACTGAAGAGATGGTGCCTTGGCACCCTTGCCTGGAACTCGTTAGCAACTGCGAGCAG
AAGCTTTCCAGTCACACATCAAGGCGCTTGATCACAATGGAAAAGGTGAAGAAATTTGAG
AATCGGGACCAGTATTCACATCTGCTAAGTGATCATTTTCTGCCATACCAAGGTCATAAT
TCCTTCCGTGAGAAATATTTTAGTGGGGTAACAAAAAGAATTGCCAAGGAAGAAAAATCC
ACCCAGGAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 463 |
| Molecular Weight
| 53420.6 |
| Theoretical pI
| 7.88 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>tRNA guanosine-2'-O-methyltransferase TRM11 homolog
MALSCTLNRYLLLMAQEHLEFRLPEIKSLLLLFGGQFASSQETYGKSPFWILSIPSEDIA
RNLMKRTVCAKSIFELWGHGQSPEELYSSLKNYPVEKMVPFLHSDSTYKIKIHTFNKTLT
QEEKIKRIDALEFLPFEGKVNLKKPQHVFSVLEDYGLDPNCIPENPHNIYFGRWIADGQR
ELIESYSVKKRHFIGNTSMDAGLSFIMANHGKVKENDIVFDPFVGTGGLLIACAHFGAYV
YGTDIDYNTVHGLGKATRKNQKWRGPDENIRANLRQYGLEKYYLDVLVSDASKPSWRKGT
YFDAIITDPPYGIRESTRRTGSQKEIPKGIEKWEKCPESHVPVSLSYHLSDMFLDLLNFA
AETLVLGGRLVYWLPVYTPEYTEEMVPWHPCLELVSNCEQKLSSHTSRRLITMEKVKKFE
NRDQYSHLLSDHFLPYQGHNSFREKYFSGVTKRIAKEEKSTQE
|
| External Links |
|---|
| GenBank ID Protein
| 94420683 |
| UniProtKB/Swiss-Prot ID
| Q7Z4G4 |
| UniProtKB/Swiss-Prot Entry Name
| TRM11_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001031712.2 |
| GeneCard ID
| TRMT11 |
| GenAtlas ID
| TRMT11 |
| HGNC ID
| HGNC:21080 |
| References |
|---|
| General References
| Not Available |