Cannabis Compound Database: Showing Protein pre-rRNA processing protein FTSJ3 (CDBP04224)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP04224

Secondary Accession Numbers

Not Available

Name

pre-rRNA processing protein FTSJ3

Description

Not Available

Synonyms

Protein ftsJ homolog 3
rRNA (uridine-2'-O-)-methyltransferase 3
2'-O-ribose RNA methyltransferase SPB1 homolog
Putative rRNA methyltransferase 3

Gene Name

FTSJ3

Protein Type

Enzyme

Biological Properties

General Function

Involved in methyltransferase activity

Specific Function

Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.

GO Classification

Biological Process
RNA methylation
rRNA processing
Cellular Component
nucleolus
Component
intracellular membrane-bounded organelle
nucleus
organelle
membrane-bounded organelle
Function
binding
catalytic activity
transferase activity
nucleic acid binding
transferase activity, transferring one-carbon groups
methyltransferase activity
Molecular Function
methyltransferase activity
Process
rrna metabolic process
rrna processing
methylation
rrna modification
rrna methylation
rna metabolic process
ncrna metabolic process
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
cellular metabolic process
one-carbon metabolic process

Cellular Location

Nucleus
nucleolus

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

17q23.3

SNPs

FTSJ3

Gene Sequence

>2544 bp
ATGGGCAAGAAGGGCAAAGTTGGCAAGAGCCGACGAGACAAGTTTTATCACTTGGCGAAG
GAGACGGGTTACCGTTCCCGATCTGCTTTCAAGCTGATCCAGCTCAATCGCCGCTTTCAG
TTCCTGCAGAAAGCCCGAGCCTTGCTGGACCTGTGTGCTGCGCCAGGGGGATGGCTGCAG
GTAGCTGCCAAGTTTATGCCTGTATCCAGCCTTATTGTGGGAGTGGACCTGGTTCCAATC
AAGCCTCTCCCCAATGTGGTGACTCTCCAGCAGGACATCACAACAGAACGTTGTAGGCAG
GCCCTGAGGAAGGAGCTGAAGACCTGGAAGGTTGATGTTGTGCTCAATGATGGGGCCCCC
AACGTTGGGGCTAGCTGGGTCCATGATGCTTACTCACAAGCCCATTTGACACTGATGGCT
CTACGTTTGGCTTGTGACTTTTTGGCCCGTGGTGGCAGCTTCATCACAAAGGTTTTCCGT
TCTCGTGACTATCAGCCTCTGCTATGGATCTTTCAGCAGCTGTTCCGCCGTGTCCAGGCC
ACCAAGCCCCAAGCCTCTCGCCATGAATCTGCAGAGATCTTTGTAGTCTGCCAAGGATTC
CTGGCCCCTGACAAGGTTGACAGTAAATTCTTTGACCCCAAATTTGCCTTTAAGGAGGTT
GAAGTTCAGGCTAAGACCGTTACTGAATTGGTTACTAAGAAGAAGCCAAAGGCTGAAGGC
TATGCTGAGGGTGACCTCACTCTCTATCACCGTACCTCAGTCACTGACTTCCTCCGAGCT
GCCAACCCTGTTGACTTCCTCTCCAAGGCCAGCGAAATCATGGTAGATGATGAAGAGTTG
GCACAGCATCCAGCTACCACTGAGGACATACGGGTGTGCTGTCAGGACATCAGAGTGTTG
GGGCGCAAGGAGCTCAGGTCGCTACTAAACTGGAGAACAAAACTTCGGCGATATGTGGCC
AAGAAGCTGAAAGAACAAGCAAAGGCACTGGACATCAGCCTCAGCTCTGGAGAGGAAGAT
GAAGGTGATGAGGAGGACTCAACAGCTGGAACCACAAAGCAGCCCTCTAAGGAGGAGGAG
GAAGAGGAGGAGGAGGAACAACTGAACCAGACCTTGGCAGAAATGAAGGCCCAGGAGGTG
GCGGAATTGAAGAGGAAGAAAAAGAAGCTGTTGCGTGAGCAGAGAAAGCAGCGGGAGCGT
GTGGAGCTGAAGATGGATCTGCCTGGGGTTTCCATTGCAGACGAGGGGGAGACTGGCATG
TTCTCCTTGAGCACCATCCGGGGTCACCAGTTATTAGAGGAAGTAACACAAGGGGATATG
AGTGCAGCAGACACATTTCTGTCCGATCTGCCAAGGGATGATATCTATGTGTCAGATGTT
GAGGACGACGGTGATGACACATCTCTGGATAGTGACCTGGATCCAGAGGAGCTGGCAGGA
GTCAGGGGACATCAGGGTCTAAGGGACCAAAAGCGTATGCGACTTACTGAAGTGCAAGAT
GATAAAGAGGAGGAGGAGGAGGAGAATCCACTGCTGGTACCACTGGAGGAAAAGGCAGTA
CTGCAGGAAGAACAAGCCAACCTGTGGTTCTCAAAGGGCAGCTTTGCTGGGATCGAGGAC
GATGCCGATGAGGCCCTGGAGATCAGTCAGGCCCAGCTGTTATTTGAGAACCGGCGGAAG
GGACGGCAGCAGCAGCAGAAGCAGCAGCTGCCACAGACACCCCCTTCCTGTTTGAAGACT
GAGATAATGTCTCCCCTGTACCAAGATGAAGCCCCTAAGGGAACAGAGGCTTCTTCGGGG
ACAGAAGCTGCCACTGGCCTTGAAGGGGAAGAAAAGGATGGCATCTCAGACAGTGATAGC
AGTACTAGCAGTGAGGAAGAAGAGAGCTGGGAACCCCTCCGTGGTAAGAAGCGAAGCCGT
GGGCCTAAGTCAGATGATGACGGGTTTGAGATAGTGCCTATTGAGGACCCAGCGAAACAT
CGGATACTGGACCCCGAAGGCCTTGCTCTAGGTGCTGTTATTGCCTCTTCCAAAAAGGCC
AAGAGAGACCTCATAGATAACTCCTTCAACCGGTACACATTTAATGAGGATGAGGGGGAG
CTTCCGGAGTGGTTTGTGCAAGAGGAAAAGCAGCACCGGATACGACAGTTGCCTGTTGGT
AAGAAGGAGGTGGAGCATTACCGGAAACGCTGGCGGGAAATCAATGCACGTCCCATCAAG
AAGGTGGCTGAGGCTAAGGCTAGAAAGAAAAGGAGGATGCTGAAGAGGCTGGAGCAGACC
AGGAAGAAGGCAGAAGCCGTGGTGAACACAGTGGACATCTCAGAACGAGAGAAAGTGGCA
CAGCTGCGAAGTCTCTACAAGAAGGCTGGGCTTGGCAAGGAGAAACGCCATGTCACCTAC
GTTGTAGCCAAAAAAGGTGTGGGCCGCAAAGTGCGCCGGCCAGCTGGAGTCAGAGGTCAT
TTCAAGGTGGTGGACTCAAGGATGAAGAAGGACCAAAGAGCACAGCAACGTAAGGAACAA
AAGAAAAAACACAAACGGAAGTAA

Protein Properties

Number of Residues

847

Molecular Weight

96557.73

Theoretical pI

8.393

Pfam Domain Function

FtsJ (PF01728 )
Spb1_C (PF07780 )
DUF3381 (PF11861 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Putative rRNA methyltransferase 3
MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQ
VAAKFMPVSSLIVGVDLVPIKPLPNVVTLQQDITTERCRQALRKELKTWKVDVVLNDGAP
NVGASWVHDAYSQAHLTLMALRLACDFLARGGSFITKVFRSRDYQPLLWIFQQLFRRVQA
TKPQASRHESAEIFVVCQGFLAPDKVDSKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEG
YAEGDLTLYHRTSVTDFLRAANPVDFLSKASEIMVDDEELAQHPATTEDIRVCCQDIRVL
GRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSGEEDEGDEEDSTAGTTKQPSKEEE
EEEEEEQLNQTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGM
FSLSTIRGHQLLEEVTQGDMSAADTFLSDLPRDDIYVSDVEDDGDDTSLDSDLDPEELAG
VRGHQGLRDQKRMRLTEVQDDKEEEEEENPLLVPLEEKAVLQEEQANLWFSKGSFAGIED
DADEALEISQAQLLFENRRKGRQQQQKQQLPQTPPSCLKTEIMSPLYQDEAPKGTEASSG
TEAATGLEGEEKDGISDSDSSTSSEEEESWEPLRGKKRSRGPKSDDDGFEIVPIEDPAKH
RILDPEGLALGAVIASSKKAKRDLIDNSFNRYTFNEDEGELPEWFVQEEKQHRIRQLPVG
KKEVEHYRKRWREINARPIKKVAEAKARKKRRMLKRLEQTRKKAEAVVNTVDISEREKVA
QLRSLYKKAGLGKEKRHVTYVVAKKGVGRKVRRPAGVRGHFKVVDSRMKKDQRAQQRKEQ
KKKHKRK

External Links

GenBank ID Protein

194097365

UniProtKB/Swiss-Prot ID

Q8IY81

UniProtKB/Swiss-Prot Entry Name

RRMJ3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_017647.3

GeneCard ID