| Identification |
|---|
| HMDB Protein ID
| CDBP04222 |
| Secondary Accession Numbers
| Not Available |
| Name
| Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
| Description
| Not Available |
| Synonyms
|
- Protein ftsJ homolog 1
- rRNA (uridine-2'-O-)-methyltransferase
- 2'-O-ribose RNA methyltransferase TRM7 homolog
|
| Gene Name
| FTSJ1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in methyltransferase activity |
| Specific Function
| Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs (By similarity).
|
| GO Classification
|
| Biological Process |
| RNA methylation |
| rRNA processing |
| Function |
| binding |
| catalytic activity |
| transferase activity |
| nucleic acid binding |
| transferase activity, transferring one-carbon groups |
| methyltransferase activity |
| Molecular Function |
| methyltransferase activity |
| Process |
| one-carbon metabolic process |
| rrna metabolic process |
| rrna processing |
| methylation |
| rrna modification |
| rrna methylation |
| rna metabolic process |
| ncrna metabolic process |
| metabolic process |
| macromolecule metabolic process |
| cellular macromolecule metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| X |
| Locus
| Xp11.23 |
| SNPs
| FTSJ1 |
| Gene Sequence
|
>990 bp
ATGGGACGGACGTCAAAGGACAAGCGGGATGTCTACTACCGCCTGGCCAAGGAGAATGGC
TGGCGTGCTCGCAGCGCCTTCAAACTGCTACAACTGGATAAGGAATTCCAACTCTTCCAA
GGCGTGACACGGGCAGTTGACCTGTGTGCAGCCCCAGGCAGCTGGAGCCAGGTGCTGAGC
CAGAAGATCGGGGGCCAAGGGTCCGGCCACGTGGTGGCTGTGGACCTGCAGGCTATGGCT
CCACTACCAGGTGTGGTACAGATCCAGGGGGACATCACCCAGCTGTCCACTGCCAAGGAG
ATCATCCAGCACTTTAAGGGCTGCCCTGCGGACCTAGTGGTGTGTGACGGGGCTCCTGAT
GTAACCGGTCTCCATGATGTTGATGAGTATATGCAGGCCCAGCTCCTCCTAGCTGCTCTG
AACATTGCTACACATGTCCTGAAGCCAGGGGGCTGCTTTGTGGCCAAGATATTCCGAGGC
CGGGATGTGACGCTCCTCTACAGCCAGCTGCAGGTCTTCTTCTCCAGCGTGCTGTGTGCC
AAGCCCAGGAGCAGCCGGAACTCTAGCATCGAGGCCTTCGCTGTCTGTCAGGGCTATGAC
CCTCCCGAGGGCTTCATCCCGGACCTGAGCAAACCCCTGCTGGACCATTCTTACGACCCA
GATTTCAACCAGCTGGATGGTCCCACCCGCATCATTGTGCCTTTTGTGACCTGTGGGGAC
CTGAGCTCCTATGATTCGGACCGCAGTTACCCACTGGACCTAGAGGGCGGCTCAGAGTAC
AAGTACACTCCACCCACACAGCCCCCCATCTCGCCACCATACCAGGAGGCCTGCACGTTG
AAGAGGAAGGGGCAGCTGGCCAAGGAGATCCGCCCCCAGGACTGCCCCATCAGCAGAGTG
GACACGTTTCCCCAGCCCCTGGCCGCCCCTCAGTGCCACACCCTGCTGGCCCCTGAGATG
GAAGACAATGAAATGAGTTGTTCACCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 329 |
| Molecular Weight
| 36078.76 |
| Theoretical pI
| 5.695 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Putative ribosomal RNA methyltransferase 1
MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLS
QKIGGQGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGCPADLVVCDGAPD
VTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCA
KPRSSRNSSIEAFAVCQGYDPPEGFIPDLSKPLLDHSYDPDFNQLDGPTRIIVPFVTCGD
LSSYDSDRSYPLDLEGGSEYKYTPPTQPPISPPYQEACTLKRKGQLAKEIRPQDCPISRV
DTFPQPLAAPQCHTLLAPEMEDNEMSCSP
|
| External Links |
|---|
| GenBank ID Protein
| 7110661 |
| UniProtKB/Swiss-Prot ID
| Q9UET6 |
| UniProtKB/Swiss-Prot Entry Name
| RRMJ1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_012280.2 |
| GeneCard ID
| FTSJ1 |
| GenAtlas ID
| FTSJ1 |
| HGNC ID
| HGNC:13254 |
| References |
|---|
| General References
| Not Available |