| Identification |
|---|
| HMDB Protein ID
| CDBP04220 |
| Secondary Accession Numbers
| Not Available |
| Name
| Putative methyltransferase NSUN6 |
| Description
| Not Available |
| Synonyms
|
- NOL1/NOP2/Sun and PUA domain-containing protein 1
- NOL1/NOP2/Sun domain family member 6
|
| Gene Name
| NSUN6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in RNA binding |
| Specific Function
| May have S-adenosyl-L-methionine-dependent methyl- transferase activity (Potential) |
| GO Classification
|
| Function |
| binding |
| catalytic activity |
| transferase activity |
| nucleic acid binding |
| transferase activity, transferring one-carbon groups |
| methyltransferase activity |
| rna binding |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10p12.31 |
| SNPs
| NSUN6 |
| Gene Sequence
|
>1410 bp
ATGTCTATTTTCCCTAAGATATCTTTGAGACCTGAGGTTGAAAACTATCTTAAGGAAGGC
TTTATGAATAAGGAGATTGTGACTGCTTTAGGTAAACAAGAAGCAGAAAGGAAGTTTGAA
ACTTTGTTAAAGCACCTGTCACATCCTCCATCATTTACAACTGTCAGAGTGAATACACAT
TTAGCCTCAGTACAACATGTGAAAAATCTGTTACTTGATGAACTTCAGAAGCAGTTTAAT
GGATTAAGTGTTCCTATTCTTCAACATCCAGACCTTCAAGATGTGTTACTTATTCCTGTT
ATTGGACCCAGAAAGAATATTAAAAAACAACAGTGTGAAGCCATTGTTGGAGCCCAGTGT
GGCAATGCAGTTTTAAGAGGAGCCCATGTCTATGCCCCAGGAATTGTGTCAGCATCACAA
TTTATGAAAGCTGGAGATGTTATTTCTGTATACTCTGATATTAAAGGAAAATGTAAGAAA
GGAGCCAAAGAATTTGATGGAACAAAAGTATTTCTTGGAAATGGGATTTCTGAACTAAGC
CGCAAAGAAATCTTCAGTGGATTACCTGAACTGAAAGGCATGGGCATAAGAATGACAGAA
CCAGTATATCTCAGCCCTTCATTTGACAGTGTACTGCCCCGTTACTTATTTTTACAAAAT
TTGCCATCTGCCTTAGTAAGTCATGTACTAAATCCTCAACCTGGAGAGAAGATTCTAGAC
TTGTGTGCAGCACCTGGAGGGAAAACAACACACATTGCAGCACTAATGCATGATCAGGGA
GAAGTTATAGCACTGGATAAAATCTTCAACAAAGTAGAAAAAATCAAACAGAATGCCTTA
TTGTTAGGGCTGAATTCCATCAGGGCATTTTGTTTTGATGGAACAAAGGCGGTTAAACTT
GATATGGTGGAGGACACAGAAGGAGAACCTCCATTTCTACCAGAATCCTTTGACCGAATT
CTTCTGGATGCACCCTGTAGTGGAATGGGACAGAGACCAAACATGGCCTGTACTTGGTCT
GTGAAGGAAGTGGCATCATATCAGCCATTACAGCGAAAACTCTTCACTGCAGCGGTTCAG
CTGCTGAAGCCAGAGGGTGTGCTGGTTTATAGCACGTGCACTATAACACTGGCCGAAAAT
GAAGAACAGGTTGCCTGGGCCCTGACAAAATTTCCTTGCCTTCAGCTTCAGCCCCAGGAA
CCGCAGATTGGAGGAGAAGGAATGAGGGGAGCTGGGCTCTCATGTGAACAGTTGAAACAG
CTGCAGCGATTTGATCCATCGGCTGTGCCATTACCGGACACTGACATGGACTCTCTTAGA
GAGGCCAGAAGAGAAGACATGTTGCGTCTGGCTAATAAGGACTCTATAGGTTTTTTTATT
GCAAAATTTGTAAAATGCAAAAGCACATAG
|
| Protein Properties |
|---|
| Number of Residues
| 469 |
| Molecular Weight
| 51769.8 |
| Theoretical pI
| 8.05 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Putative methyltransferase NSUN6
MSIFPKISLRPEVENYLKEGFMNKEIVTALGKQEAERKFETLLKHLSHPPSFTTVRVNTH
LASVQHVKNLLLDELQKQFNGLSVPILQHPDLQDVLLIPVIGPRKNIKKQQCEAIVGAQC
GNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS
RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILD
LCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKL
DMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ
LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQ
LQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST
|
| External Links |
|---|
| GenBank ID Protein
| 18676896 |
| UniProtKB/Swiss-Prot ID
| Q8TEA1 |
| UniProtKB/Swiss-Prot Entry Name
| NSUN6_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK074323 |
| GeneCard ID
| NSUN6 |
| GenAtlas ID
| NSUN6 |
| HGNC ID
| HGNC:23529 |
| References |
|---|
| General References
| Not Available |