| Identification |
|---|
| HMDB Protein ID
| CDBP04169 |
| Secondary Accession Numbers
| Not Available |
| Name
| Putative tyrosine-protein phosphatase TPTE |
| Description
| Not Available |
| Synonyms
|
- CT44
- Cancer/testis antigen 44
- Transmembrane phosphatase with tensin homology
- Tumor antigen BJ-HCC-5
|
| Gene Name
| TPTE |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein tyrosine/serine/threonine phosphatase activity |
| Specific Function
| Could be involved in signal transduction.
|
| GO Classification
|
| Biological Process |
| signal transduction |
| Cellular Component |
| integral to membrane |
| Component |
| membrane |
| cell part |
| Function |
| ion channel activity |
| phosphoprotein phosphatase activity |
| protein tyrosine phosphatase activity |
| hydrolase activity, acting on ester bonds |
| catalytic activity |
| hydrolase activity |
| phosphoric ester hydrolase activity |
| phosphatase activity |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| protein tyrosine/serine/threonine phosphatase activity |
| transporter activity |
| Molecular Function |
| protein tyrosine/serine/threonine phosphatase activity |
| ion channel activity |
| protein tyrosine phosphatase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| dephosphorylation |
| protein amino acid dephosphorylation |
| metabolic process |
| establishment of localization |
| transport |
| cellular metabolic process |
| transmembrane transport |
| ion transport |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 21 |
| Locus
| 21p11 |
| SNPs
| TPTE |
| Gene Sequence
|
>1656 bp
ATGAATGAAAGTCCTGATCCGACTGACCTGGCGGGAGTCATCATTGAGCTCGGCCCCAAT
GACAGTCCACAGACAAGTGAATTTAAAGGAGCAACCGAGGAGGCACCTGCGAAAGAAAGC
CCACACACAAGTGAATTTAAAGGAGCAGCCCGGGTGTCACCTATCAGTGAAAGTGTGTTA
GCACGACTTTCCAAGTTTGAAGTTGAAGATGCTGAAAATGTTGCTTCATATGACAGCAAG
ATTAAGAAAATTGTGCATTCAATTGTATCATCCTTTGCATTTGGACTATTTGGAGTTTTC
CTGGTCTTACTGGATGTCACTCTCATCCTTGCCGACCTAATTTTCACTGACAGCAAACTT
TATATTCCTTTGGAGTATCGTTCTATTTCTCTAGCTATTGCCTTATTTTTTCTCATGGAT
GTTCTTCTTCGAGTATTTGTAGAAAGGAGACAGCAGTATTTTTCTGACTTATTTAACATT
TTAGATACTGCCATTATTGTGATTCTTCTGCTGGTTGATGTCGTTTACATTTTTTTTGAC
ATTAAGTTGCTTAGGAATATTCCCAGATGGACACATTTACTTCGACTTCTACGACTTATT
ATTCTGTTAAGAATTTTTCATCTGTTTCATCAAAAAAGACAACTTGAAAAGCTGATAAGA
AGGCGGGTTTCAGAAAACAAAAGGCGATACACAAGGGATGGATTTGACCTAGACCTCACT
TACGTTACAGAACGTATTATTGCTATGTCATTTCCATCTTCTGGAAGGCAGTCTTTCTAT
AGAAATCCAATCAAGGAAGTTGTGCGGTTTCTAGATAAGAAACACCGAAACCACTATCGA
GTCTACAATCTATGCAGTGAAAGAGCTTACGATCCTAAGCACTTCCATAATAGGGTCGTT
AGAATCATGATTGATGATCATAATGTCCCCACTCTACATCAGATGGTGGTTTTCACCAAG
GAAGTAAATGAGTGGATGGCTCAAGATCTTGAAAACATCGTAGCGATTCACTGTAAAGGA
GGCACAGATAGAACAGGAACTATGGTTTGTGCCTTCCTTATTGCCTCTGAAATATGTTCA
ACTGCAAAGGAAAGCCTGTATTATTTTGGAGAAAGGCGAACAGATAAAACCCACAGCGAA
AAATTTCAGGGAGTAGAAACTCCTTCTCAGAAGAGATATGTTGCATATTTTGCACAAGTG
AAACATCTCTACAACTGGAATCTCCCTCCAAGACGGATACTCTTTATAAAACACTTCATT
ATTTATTCGATTCCTCGTTATGTACGTGATCTAAAAATCCAAATAGAAATGGAGAAAAAG
GTTGTCTTTTCCACTATTTCATTAGGAAAATGTTCGGTACTTGATAACATTACAACAGAC
AAAATATTAATTGATGTATTCGACGGTCCACCTCTGTATGATGATGTGAAAGTGCAGTTT
TTCTATTCGAATCTTCCTACATACTATGACAATTGCTCATTTTACTTCTGGTTGCACACA
TCTTTTATTGAAAATAACAGGCTTTATCTACCAAAAAATGAATTGGATAATCTACATAAA
CAAAAAGCACGGAGAATTTATCCATCAGATTTTGCCGTGGAGATACTTTTTGGCGAGAAA
ATGACTTCCAGTGATGTTGTAGCTGGATCCGATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 551 |
| Molecular Weight
| 62440.68 |
| Theoretical pI
| 8.452 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Putative tyrosine-protein phosphatase TPTE
MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL
ARLSKFEVEDAENVASYDSKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKL
YIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFFD
IKLLRNIPRWTHLLRLLRLIILLRIFHLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLT
YVTERIIAMSFPSSGRQSFYRNPIKEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVV
RIMIDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHCKGGTDRTGTMVCAFLIASEICS
TAKESLYYFGERRTDKTHSEKFQGVKTPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFI
IYSIPRYVRDLKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVFDGPPLYDDVKVQF
FYSNLPTYYDNCSFYFWLHTSFIENNRLYLPKNELDNLHKQKARRIYPSDFAVEILFGEK
MTSSDVVAGSD
|
| External Links |
|---|
| GenBank ID Protein
| 3549240 |
| UniProtKB/Swiss-Prot ID
| P56180 |
| UniProtKB/Swiss-Prot Entry Name
| TPTE_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF007118 |
| GeneCard ID
| TPTE |
| GenAtlas ID
| TPTE |
| HGNC ID
| HGNC:12023 |
| References |
|---|
| General References
| Not Available |