| Identification |
|---|
| HMDB Protein ID
| CDBP04113 |
| Secondary Accession Numbers
| Not Available |
| Name
| Dual specificity protein phosphatase 12 |
| Description
| Not Available |
| Synonyms
|
- Dual specificity tyrosine phosphatase YVH1
|
| Gene Name
| DUSP12 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phosphatase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| positive regulation of glucokinase activity |
| Cellular Component |
| cytoplasm |
| nucleus |
| Component |
| cell part |
| intracellular |
| Function |
| cation binding |
| metal ion binding |
| hydrolase activity, acting on ester bonds |
| binding |
| catalytic activity |
| hydrolase activity |
| transition metal ion binding |
| zinc ion binding |
| phosphoric ester hydrolase activity |
| phosphatase activity |
| protein tyrosine/serine/threonine phosphatase activity |
| phosphoprotein phosphatase activity |
| ion binding |
| Molecular Function |
| protein tyrosine/serine/threonine phosphatase activity |
| metal ion binding |
| zinc ion binding |
| protein tyrosine phosphatase activity |
| Process |
| phosphate metabolic process |
| dephosphorylation |
| protein amino acid dephosphorylation |
| metabolic process |
| cellular metabolic process |
| phosphorus metabolic process |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| 1q21-q22 |
| SNPs
| DUSP12 |
| Gene Sequence
|
>1023 bp
ATGTTGGAGGCTCCGGGCCCGAGTGATGGCTGCGAGCTCAGCAACCCCAGCGCCAGCAGA
GTCAGCTGTGCCGGGCAGATGCTGGAAGTGCAGCCAGGATTGTATTTCGGTGGGGCCGCG
GCCGTCGCGGAGCCAGATCACCTGAGGGAAGCGGGCATCACGGCCGTGCTAACAGTGGAC
TCGGAGGAGCCCAGCTTCAAGGCGGGGCCTGGGGTCGAGGATCTATGGCGCCTCTTCGTG
CCAGCGCTGGACAAACCCGAGACGGACCTACTCAGCCATCTGGACCGGTGCGTGGCCTTC
ATCGGTCAGGCCCGCGCTGAGGGCCGTGCGGTGTTGGTGCACTGTCATGCAGGAGTCAGT
CGAAGTGTGGCCATAATAACTGCTTTTCTCATGAAGACTGACCAACTTCCCTTTGAAAAA
GCCTATGAAAAGCTCCAGATTCTCAAACCAGAGGCTAAGATGAATGAGGGGTTTGAGTGG
CAACTGAAATTATACCAGGCAATGGGATATGAAGTGGATACCTCTAGTGCAATTTATAAG
CAATATCGTTTACAAAAGGTTACAGAGAAGTATCCAGAATTGCAGAATTTACCTCAAGAA
CTCTTTGCTGTTGACCCAACTACCGTTTCACAAGGATTGAAAGATGAGGTTCTCTACAAG
TGTAGAAAGTGCAGGCGATCATTATTTCGAAGTTCTAGTATTCTGGATCACCGTGAAGGA
AGTGGACCTATAGCCTTTGCCCACAAGAGAATGACACCATCTTCCATGCTTACCACAGGG
AGGCAAGCTCAATGTACATCTTATTTCATTGAACCTGTACAGTGGATGGAATCTGCTTTG
TTGGGAGTGATGGATGGACAGCTTCTTTGCCCAAAATGCAGTGCCAAGTTGGGTTCCTTC
AACTGGTATGGTGAACAGTGCTCTTGTGGTAGGTGGATAACACCTGCTTTTCAAATACAT
AAGAATAGAGTGGATGAAATGAAAATATTGCCTGTTTTGGGATCACAAACAGGAAAAATA
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 340 |
| Molecular Weight
| 37687.015 |
| Theoretical pI
| 6.844 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Dual specificity protein phosphatase 12
MLEAPGPSDGCELSNPSASRVSCAGQMLEVQPGLYFGGAAAVAEPDHLREAGITAVLTVD
SEEPSFKAGPGVEDLWRLFVPALDKPETDLLSHLDRCVAFIGQARAEGRAVLVHCHAGVS
RSVAIITAFLMKTDQLPFEKAYEKLQILKPEAKMNEGFEWQLKLYQAMGYEVDTSSAIYK
QYRLQKVTEKYPELQNLPQELFAVDPTTVSQGLKDEVLYKCRKCRRSLFRSSSILDHREG
SGPIAFAHKRMTPSSMLTTGRQAQCTSYFIEPVQWMESALLGVMDGQLLCPKCSAKLGSF
NWYGEQCSCGRWITPAFQIHKNRVDEMKILPVLGSQTGKI
|
| External Links |
|---|
| GenBank ID Protein
| 5764099 |
| UniProtKB/Swiss-Prot ID
| Q9UNI6 |
| UniProtKB/Swiss-Prot Entry Name
| DUS12_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF119226 |
| GeneCard ID
| DUSP12 |
| GenAtlas ID
| DUSP12 |
| HGNC ID
| HGNC:3067 |
| References |
|---|
| General References
| Not Available |