| Identification |
|---|
| HMDB Protein ID
| CDBP04094 |
| Secondary Accession Numbers
| Not Available |
| Name
| tRNA 2'-phosphotransferase 1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| TRPT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in transferase activity, transferring phosphorus-containing groups |
| Specific Function
| Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate (Probable).
|
| GO Classification
|
| Biological Process |
| tRNA splicing, via endonucleolytic cleavage and ligation |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| Molecular Function |
| transferase activity, transferring phosphorus-containing groups |
| tRNA 2'-phosphotransferase activity |
| Process |
| rna metabolic process |
| metabolic process |
| macromolecule metabolic process |
| cellular macromolecule metabolic process |
| rna processing |
| rna splicing |
| rna splicing, via endonucleolytic cleavage and ligation |
| trna splicing, via endonucleolytic cleavage and ligation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 11 |
| Locus
| 11q13.1 |
| SNPs
| TRPT1 |
| Gene Sequence
|
>762 bp
ATGAACTTCTCTGGAGGAGGGAGGCAGGAAGCAGCAGGGTCCAGGGGTAGAAGGGCTCCC
AGACCCCGAGAACAGGACCGAGACGTGCAGCTGTCCAAGGCTCTGTCCTATGCCCTGCGC
CATGGGGCCTTGAAGCTGGGGCTTCCCATGGGAGCTGATGGCTTCGTGCCCCTGGGCACC
CTCCTGCAGTTGCCCCAGTTCCGCGGCTTCTCTGCTGAAGATGTGCAGCGCGTGGTGGAC
ACCAATAGGAAGCAGCGGTTCGCCCTGCAGCTGGGGGATCCCAGCACTGGCCTTCTCATC
CGGGCCAACCAGGGCCATTCCCTGCAGGTACCTAAGTTGGAGCTGATGCCCCTGGAGACA
CCGCAGGCCCTGCCCCCGATGCTAGTCCATGGTACATTCTGGAAGCACTGGCCATCCATC
CTACTCAAAGGCCTGTCCTGCCAGGGAAGGACGCACATTCACCTGGCCCCAGGACTGCCT
GGAGACCCCGGTATCATCAGTGGCATGCGGTCCCATTGTGAAATAGCTGTGTTCATCGAT
GGACCCCTGGCTCTGGCAGATGGAATACCCTTCTTCCGCTCTGCCAATGGGGTGATTCTG
ACTCCAGGGAATACTGATGGCTTCCTCCTTCCCAAGTACTTCAAGGAGGCCCTGCAGCTA
CGCCCTACCCGAAAGCCCCTTTCCTTGGCTGGTGATGAAGAGACAGAGTGTCAGAGTAGC
CCCAAGCACAGCTCCAGAGAAAGGAGGAGGATCCAACAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 253 |
| Molecular Weight
| 27741.69 |
| Theoretical pI
| 9.985 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>tRNA 2'-phosphotransferase 1
MNFSGGGRQEAAGSRGRRAPRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGT
LLQLPQFRGFSAEDVQRVVDTNRKQRFALQLGDPSTGLLIRANQGHSLQVPKLELMPLET
PQALPPMLVHGTFWKHWPSILLKGLSCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFID
GPLALADGIPFFRSANGVILTPGNTDGFLLPKYFKEALQLRPTRKPLSLAGDEETECQSS
PKHSSRERRRIQQ
|
| External Links |
|---|
| GenBank ID Protein
| 238550153 |
| UniProtKB/Swiss-Prot ID
| Q86TN4 |
| UniProtKB/Swiss-Prot Entry Name
| TRPT1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001033678.3 |
| GeneCard ID
| TRPT1 |
| GenAtlas ID
| TRPT1 |
| HGNC ID
| HGNC:20316 |
| References |
|---|
| General References
| Not Available |