Showing Protein Poly [ADP-ribose] polymerase 8 (CDBP04083)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP04083
Secondary Accession Numbers Not Available
Name Poly [ADP-ribose] polymerase 8
Description Not Available
Synonyms
  1. PARP-8
  2. ADP-ribosyltransferase diphtheria toxin-like 16
  3. ARTD16
Gene Name PARP8
Protein Type Enzyme
Biological Properties
General Function Involved in NAD+ ADP-ribosyltransferase activity
Specific Function Not Available
GO Classification
Cellular Component
intracellular
Function
catalytic activity
transferase activity
nad+ adp-ribosyltransferase activity
transferase activity, transferring pentosyl groups
transferase activity, transferring glycosyl groups
Molecular Function
NAD+ ADP-ribosyltransferase activity
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 5
Locus 5q11.1
SNPs PARP8
Gene Sequence 
>2565 bp
ATGGGGATGTGTTCAAGGCAAGAGCGAATTCAGAAGGATATCGACGTCGTGATCCAGAAG
TCCAGAGCTGAGAAGGACTGCCTGTTTGCAGATTTCAGATACTCTGACTCCACCTTTACT
TTTACCTACGTTGGCGGCCCCAGAAGTGTATCCTACTCAGTACATGTATCTGAAGATTAC
CCAGATAATACATATGTGTCAAGTTCAGAGAATGATGAAGATGTGCTAGTTACTACAGAG
CCAATACCAGTAATTTTTCATAGAATAGCAACAGAATTAAGAAAAACAAATGACATTAAC
TGTTGCTTATCCATAAAATCCAAATTACAAAAGGAAAATGGGGAGGAATCAAGACAGAAT
AGTACAGTGGAGGAAGATTCTGAAGGTGACAATGATTCCGAAGAATTTTATTACGGAGGG
CAGGTGAACTATGATGGGGAACTGCACAAGCACCCACAACTGGAAGCTGATTTGTCAGCA
GTTAGAGAGATATATGGGCCACATGCAGTTTCTCTCAGGGAATATGGAGCCATTGATGAT
GTAGATATTGATCTGCATATCGATGTTAGCTTTCTTGATGAGGAGATTGCTGTGGCTTGG
GAAGTAATTCGAACAGAACCTATAATTGTTCGACTACACTGTTCACTTACACAGTATTTA
AATGGCCCAGTGCCCACTGTTGATGTCTTTCAGATTTCCACAAAAGAGCGATTTGGATTG
GGACATCAGCTGAAAAAAATCATGCAGACATTTGTTACACAGCAGTGGAAACAGAGCAAA
GAAAAATCCAATTGCCTGCACAATAAAAAGTTGTCAGAGAAGAAAGTGAAGTCTCCCCTG
CATTTATTTTCTACTTTGCGCAGGTCGCCAAGTTATCCTCCCCCTGGTTGTGGCAAAAGC
AAATCCAAACTGAAATCTGAGCAGGACGGAATCTCCAAAACGCATAAGCTGCTGCGGAGG
ACTTGTTCCAGCACAGTCAAGACTGATGATGTGTGTGTCACAAAGTCACACAGGACCTTT
GGCCGCTCCTTGTCCAGCGATCCCAGGGCGGAGCAGGCTATGACAGCAATTAAATCGCAC
AAACTTTTGAACCGTCCTTGCCCTGCAGCTGTTAAGTCAGAGGAATGCCTAACTCTAAAG
TCGCATAGACTATTGACTCGATCTTGTTCTGGAGATCCACGATGTGAGCACAACACAAAC
TTGAAGCCCCATAAACTGTTAAGCAGGTCTTACTCTAGTAATCTCAGAATGGAAGAATTA
TATGGACTGAAAAATCACAAATTGCTCAGCAAGTCCTACTCCAGTGCCCCCAAGTCATCC
AAAACTGAGCTTTTCAAGGAACCTAACGCAGAGGGCAGGAGGCTCTCTCTTACCTCAGGG
CTTATTGGTATCCTAACACCATCTTCATCTTCATCTTCTCAGCTTGCTCCAAATGGTGCA
AAATGCATTCCAGTACGAGACCGTGGCTTCCTGGTGCAGACAATTGAGTTTGCTGAACAG
CGGATCCCTGTATTAAATGAATATTGTGTGGTTTGTGATGAGCCACATGTGTTTCAAAAT
GGCCCTATGCTTAGGCCTACCGTATGTGAACGGGAGCTGTGTGTGTTTGCTTTTCAAACC
CTGGGAGTAATGAATGAAGCTGCTGATGAAATAGCAACTGGAGCTCAGGTGGTAGATCTA
CTAGTATCCATGTGTAGGTCTGCGTTGGAATCTCCTAGAAAAGTTGTGATTTTCGAGCCA
TATCCTTCTGTGGTAGATCCTAATGATCCTCAGATGTTGGCCTTCAACCCCAGGAAAAAG
AACTATGATCGAGTAATGAAAGCACTGGATAGCATAACTTCTATCAGAGAAATGACACAA
GCACCATATCTGGAAATCAAGAAGCAAATGGATAAACAGGACCCCCTTGCTCATCCCTTA
CTGCAATGGGTTATATCAAGTAATAGATCACATATTGTGAAACTGCCAGTTAACAGGCAA
TTGAAGTTTATGCATACTCCACATCAGTTCCTTCTTCTCAGCAGTCCACCAGCCAAAGAA
TCCAATTTTAGAGCTGCTAAAAAACTCTTTGGAAGCACCTTTGCATTTCATGGCTCACAC
ATTGAAAACTGGCACTCCATCCTGAGGAATGGTCTGGTTGTTGCTTCTAATACACGATTG
CAGCTCCATGGTGCAATGTATGGAAGTGGAATCTATCTTAGTCCAATGTCAAGCATATCA
TTTGGTTACTCAGGGATGAACAAGAAACAGAAGGTGTCAGCCAAGGACGAGCCAGCTTCA
AGCAGTAAAAGCAGCAATACATCACAGTCACAGAAAAAAGGACAGCAATCCCAATTCCTG
CAAAGCCGTAACTTAAAATGCATAGCCTTATGTGAAGTGATCACCTCATCTGACCTGCAC
AAACATGGAGAGATATGGGTTGTCCCCAATACTGACCATGTCTGCACACGATTCTTTTTC
GTCTATGAAGACGGCCAAGTGGGAGATGCAAATATTAATACACAAGAAGGAGGCATTCAC
AAAGAGATCCTCCGAGTAATTGGTAATCAAACTGCTACTGGTTAA
Protein Properties
Number of Residues 854
Molecular Weight 95870.105
Theoretical pI 8.279
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Poly [ADP-ribose] polymerase 8
MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPRSVSYSVHVSEDY
PDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCCLSIKSKLQKENGEESRQN
STVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLREYGAIDD
VDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGL
GHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKVKSPLHLFSTLRRSPSYPPPGCGKS
KSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSSDPRAEQAMTAIKSH
KLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEEL
YGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSSSSSQLAPNGA
KCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQT
LGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKK
NYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQ
LKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRL
QLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFL
QSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIH
KEILRVIGNQTATG
GenBank ID Protein 295844829
UniProtKB/Swiss-Prot ID Q8N3A8
UniProtKB/Swiss-Prot Entry Name PARP8_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001178055.1
GeneCard ID PARP8
GenAtlas ID PARP8
HGNC ID HGNC:26124
References
General References Not Available