| Identification |
|---|
| HMDB Protein ID
| CDBP04080 |
| Secondary Accession Numbers
| Not Available |
| Name
| Poly [ADP-ribose] polymerase 15 |
| Description
| Not Available |
| Synonyms
|
- B-aggressive lymphoma protein 3
- PARP-15
- ADP-ribosyltransferase diphtheria toxin-like 7
- ARTD7
|
| Gene Name
| PARP15 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in NAD+ ADP-ribosyltransferase activity |
| Specific Function
| Transcriptional repressor. Has ADP-ribosyltransferase activity.
|
| GO Classification
|
| Biological Process |
| regulation of transcription, DNA-dependent |
| transcription, DNA-dependent |
| Cellular Component |
| nucleus |
| Function |
| catalytic activity |
| transferase activity |
| nad+ adp-ribosyltransferase activity |
| transferase activity, transferring pentosyl groups |
| transferase activity, transferring glycosyl groups |
| Molecular Function |
| NAD+ ADP-ribosyltransferase activity |
|
| Cellular Location
|
- Nucleus (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| 3q21.1 |
| SNPs
| PARP15 |
| Gene Sequence
|
>1971 bp
ATGCACGGAGTTGCAGGTGTTACTTCCAGAGCCGGACGAGATCGGGAGGCGGGGAGCATG
CTGCCGGCCGGGAACCGTGGGGCGCGGAAGGCCTCCCGGCGCTCTTCCTCCCGGAGTATG
TCCAGAGACAACAAGTTCAGCAAGAAAGATTGTCTTTCAATCAGGAATGTTGTAGCTTCA
ATCCAAACCAAAGAAGGTCTGAATCTCAAGTTGATAAGTGGAGATGTTCTGTACATCTGG
GCCGATGTCATTGTCAACAGCGTTCCCATGAATCTTCAGCTTGGAGGAGGACCACTATCT
CGGGCATTTTTGCAGAAAGCTGGTCCCATGCTCCAGAAAGAGTTAGATGACAGAAGGCGG
GAAACAGAGGAAAAAGTAGGTAACATATTCATGACAAGCGGCTGCAATCTGGACTGCAAA
GCTGTGCTCCATGCTGTGGCTCCATACTGGAATAATGGAGCAGAGACTTCTTGGCAGATC
ATGGCAAATATAATCAAGAAATGTTTGACAACTGTAGAAGTGCTATCTTTCTCATCAATC
ACATTTCCCATGATTGGAACAGGAAGTTTGCAGTTTCCCAAAGCTGTTTTTGCTAAACTA
ATCCTTTCAGAAGTGTTCGAATACAGTAGCAGCACAAGGCCGATAACTAGCCCTTTACAA
GAAGTCCACTTTCTGGTATATACAAATGACGATGAAGGCTGTCAGGCATTTTTAGATGAA
TTCACTAACTGGTCAAGAATAAATCCCAACAAGGCCAGGATTCCCATGGCAGGAGATACC
CAAGGTGTGGTCGGGACTGTCTCTAAGCCTTGTTTCACAGCATATGAAATGAAAATCGGT
GCAATTACTTTTCAGGTTGCTACTGGAGATATAGCCACTGAACAGGTAGATGTTATTGTA
AACTCAACAGCAAGGACATTTAATCGGAAATCAGGTGTGTCAAGAGCTATTTTAGAAGGT
GCTGGACAAGCTGTGGAAAGTGAATGTGCTGTACTAGCTGCACAGCCTCACAGAGATTTT
ATAATTACACCAGGTGGATGCTTAAAGTGCAAAATAATAATTCATGTTCCTGGGGGAAAA
GATGTCAGGAAAACGGTCACCAGTGTTCTAGAAGAGTGTGAACAGAGGAAGTACACATCG
GTTTCCCTTCCAGCCATTGGAACAGGAAATGCCGGAAAAAACCCTATCACAGTTGCTGAT
AACATAATCGATGCTATTGTAGACTTCTCATCACAACATTCCACCCCATCATTAAAAACA
GTTAAAGTTGTCATTTTTCAACCTGAGCTGCTAAATATATTCTACGACAGCATGAAAAAA
AGAGACCTCTCTGCATCACTGAACTTTCAGTCCACATTCTCCATGACTACATGTAATCTT
CCTGAACACTGGACTGACATGAATCATCAGCTGTTTTGCATGGTCCAGCTAGAGCCAGGA
CAATCAGAATATAATACCATAAAGGACAAGTTCACCCGAACTTGTTCTTCCTACGCAATA
GAGAAGATTGAGAGGATACAGAATGCATTTCTCTGGCAGAGCTACCAGGTAAAGAAAAGG
CAAATGGATATCAAGAATGACCATAAGAATAATGAGAGACTCCTCTTCCATGGGACAGAT
GCAGACTCAGTGCCATATGTCAATCAGCACGGCTTTAATAGAAGTTGTGCTGGGAAAAAT
GCTGTATCCTATGGAAAAGGAACCTATTTTGCTGTGGATGCCAGTTATTCTGCCAAGGAC
ACCTACTCCAAGCCAGACAGCAATGGGAGAAAGCACATGTACGTTGTGCGAGTACTTACT
GGAGTCTTCACAAAGGGACGTGCAGGATTAGTCACCCCTCCACCCAAGAATCCTCACAAT
CCCACAGATCTCTTTGACTCAGTGACAAACAATACACGATCTCCAAAGCTATTTGTGGTA
TTCTTTGATAATCAGGCTTACCCAGAATATCTCATAACTTTCACGGCTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 656 |
| Molecular Weight
| 74575.465 |
| Theoretical pI
| 8.815 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Poly [ADP-ribose] polymerase 15
MHGVAGVTSRAGRDREAGSMLPAGNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVAS
IQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRR
ETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSI
TFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDE
FTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIV
NSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGGK
DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKT
VKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLFCMVQLEPG
QSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTD
ADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLT
GVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFTA
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q460N3 |
| UniProtKB/Swiss-Prot Entry Name
| PAR15_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| DQ063586 |
| GeneCard ID
| PARP15 |
| GenAtlas ID
| PARP15 |
| HGNC ID
| HGNC:26876 |
| References |
|---|
| General References
| Not Available |