| Identification |
|---|
| HMDB Protein ID
| CDBP04056 |
| Secondary Accession Numbers
| Not Available |
| Name
| Oligoribonuclease, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- RNA exonuclease 2 homolog
- Small fragment nuclease
|
| Gene Name
| REXO2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in exonuclease activity |
| Specific Function
| 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily
|
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| binding |
| catalytic activity |
| hydrolase activity |
| exonuclease activity |
| nucleic acid binding |
| nuclease activity |
| hydrolase activity, acting on ester bonds |
|
| Cellular Location
|
- Isoform 2:Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11q23.2 |
| SNPs
| REXO2 |
| Gene Sequence
|
>714 bp
ATGCTAGGCGGCTCCCTGGGCTCCAGGCTGTTGCGGGGTGTAGGTGGGAGTCACGGACGG
TTCGGGGCCCGAGGTGTCCGCGAAGGTGGCGCAGCCATGGCGGCAGGGGAGAGCATGGCT
CAGCGGATGGTCTGGGTGGACCTGGAGATGACAGGATTGGACATTGAGAAGGACCAGATT
ATTGAGATGGCCTGTCTGATAACTGACTCTGATCTCAACATTTTGGCTGAAGGTCCTAAC
CTGATTATAAAACAACCAGATGAGTTGCTGGACAGCATGTCAGATTGGTGTAAGGAGCAT
CACGGGAAGTCTGGCCTTACCAAGGCAGTGAAGGAGAGTACAATTACATTGCAGCAGGCA
GAGTATGAATTTCTGTCCTTTGTACGACAGCAGACTCCTCCAGGGCTCTGTCCACTTGCA
GGAAATTCAGTTCATGAAGATAAGAAGTTTCTTGACAAATACATGCCCCAGTTCATGAAA
CATCTTCATTATAGAATAATTGATGTGAGCACTGTTAAAGAACTGTGCAGACGCTGGTAT
CCAGAAGAATATGAATTTGCACCAAAGAAGGCTGCTTCTCATAGGGCACTTGATGACATT
AGTGAAAGCATCAAAGAGCTTCAGTTTTACCGAAATAACATCTTCAAGAAAAAAATAGAT
GAAAAGAAGAGGAAAATTATAGAAAATGGGGAAAATGAGAAGACCGTGAGTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 237 |
| Molecular Weight
| 26832.5 |
| Theoretical pI
| 6.88 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Oligoribonuclease, mitochondrial
MLGGSLGSRLLRGVGGSHGRFGARGVREGGAAMAAGESMAQRMVWVDLEMTGLDIEKDQI
IEMACLITDSDLNILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTITLQQA
EYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDKYMPQFMKHLHYRIIDVSTVKELCRRWY
PEEYEFAPKKAASHRALDDISESIKELQFYRNNIFKKKIDEKKRKIIENGENEKTVS
|
| External Links |
|---|
| GenBank ID Protein
| 224496106 |
| UniProtKB/Swiss-Prot ID
| Q9Y3B8 |
| UniProtKB/Swiss-Prot Entry Name
| ORN_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_015523.3 |
| GeneCard ID
| REXO2 |
| GenAtlas ID
| REXO2 |
| HGNC ID
| HGNC:17851 |
| References |
|---|
| General References
| Not Available |