Showing Protein GDP-fucose protein O-fucosyltransferase 1 (CDBP04055)
| Identification | |
|---|---|
| HMDB Protein ID | CDBP04055 |
| Secondary Accession Numbers | Not Available |
| Name | GDP-fucose protein O-fucosyltransferase 1 |
| Description | Not Available |
| Synonyms |
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| Gene Name | POFUT1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in peptide-O-fucosyltransferase activity |
| Specific Function | Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in EGF domains. Plays a crucial role in Notch signaling |
| GO Classification | Not Available |
| Cellular Location |
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| Pathways | Not Available |
| Gene Properties | |
| Chromosome Location | Chromosome:2 |
| Locus | 20q11 |
| SNPs | POFUT1 |
| Gene Sequence |
>1167 bp ATGGGCGCCGCCGCGTGGGCACGGCCGCTGAGCGTGTCTTTCCTGCTGCTGCTTCTGCCG CTCCCGGGGATGCCCGCGGGCTCCTGGGACCCGGCCGGTTACCTGCTCTACTGCCCCTGC ATGGGGCGCTTTGGGAACCAGGCCGATCACTTCTTGGGCTCTCTGGCATTTGCAAAGCTG CTAAACCGTACCTTGGCTGTCCCTCCTTGGATTGAGTACCAGCATCACAAGCCTCCTTTC ACCAACCTCCATGTGTCCTACCAGAAGTACTTCAAGCTGGAGCCCCTCCAGGCTTACCAT CGGGTCATCAGCTTGGAGGATTTCATGGAGAAGCTGGCACCCACCCACTGGCCCCCTGAG AAGCGGGTGGCATACTGCTTTGAGGTGGCAGCCCAGCGAAGCCCAGATAAGAAGACGTGC CCCATGAAGGAAGGAAACCCCTTTGGCCCATTCTGGGATCAGTTTCATGTGAGTTTCAAC AAGTCGGAGCTTTTTACAGGCATTTCCTTCAGTGCTTCCTACAGAGAACAATGGAGCCAG AGATTTTCTCCAAAGGAACATCCGGTGCTTGCCCTGCCAGGAGCCCCAGCCCAGTTCCCC GTCCTAGAGGAACACAGGCCACTACAGAAGTACATGGTATGGTCAGACGAAATGGTGAAG ACGGGAGAGGCCCAGATTCATGCCCACCTTGTCCGGCCCTATGTGGGCATTCATCTGCGC ATTGGCTCTGACTGGAAGAACGCCTGTGCCATGCTGAAGGACGGGACTGCAGGCTCGCAC TTCATGGCCTCTCCGCAGTGTGTGGGCTACAGCCGCAGCACAGCGGCCCCCCTCACGATG ACTATGTGCCTGCCTGACCTGAAGGAGATCCAGAGGGCTGTGAAGCTCTGGGTGAGGTCG CTGGATGCCCAGTCGGTCTACGTTGCTACTGATTCCGAGAGTTATGTGCCTGAGCTCCAA CAGCTCTTCAAAGGGAAGGTGAAGGTGGTGAGCCTGAAGCCTGAGGTGGCCCAGGTCGAC CTGTACATCCTCGGCCAAGCCGACCACTTTATTGGCAACTGTGTCTCCTCCTTCACTGCC TTTGTGAAGCGGGAGCGGGACCTCCAGGGGAGGCCGTCTTCTTTCTTCGGCATGGACAGG CCCCCTAAGCTGCGGGACGAGTTCTGA |
| Protein Properties | |
| Number of Residues | 388 |
| Molecular Weight | 43955.4 |
| Theoretical pI | 8.69 |
| Pfam Domain Function |
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| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>GDP-fucose protein O-fucosyltransferase 1 MGAAAWARPLSVSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKL LNRTLAVPPWIEYQHHKPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPE KRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQ RFSPKEHPVLALPGAPAQFPVLEEHRPLQKYMVWSDEMVKTGEAQIHAHLVRPYVGIHLR IGSDWKNACAMLKDGTAGSHFMASPQCVGYSRSTAAPLTMTMCLPDLKEIQRAVKLWVRS LDAQSVYVATDSESYVPELQQLFKGKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTA FVKRERDLQGRPSSFFGMDRPPKLRDEF |
| External Links | |
| GenBank ID Protein | 15825114 |
| UniProtKB/Swiss-Prot ID | Q9H488 |
| UniProtKB/Swiss-Prot Entry Name | OFUT1_HUMAN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF375884 |
| GeneCard ID | POFUT1 |
| GenAtlas ID | POFUT1 |
| HGNC ID | HGNC:14988 |
| References | |
| General References | Not Available |