| Identification |
| HMDB Protein ID
| CDBP04045 |
| Secondary Accession Numbers
| Not Available |
| Name
| Beta-1,3-galactosyltransferase 1 |
| Description
| Not Available |
| Synonyms
|
- Beta-1,3-GalTase 1
- Beta3Gal-T1
- Beta3GalT1
- UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1
|
| Gene Name
| B3GALT1 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in galactosyltransferase activity |
| Specific Function
| Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N- acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues |
| GO Classification
|
| Component |
| membrane |
| cell part |
| Function |
| galactosyltransferase activity |
| catalytic activity |
| transferase activity |
| transferase activity, transferring hexosyl groups |
| transferase activity, transferring glycosyl groups |
| Process |
| protein amino acid glycosylation |
| metabolic process |
| macromolecule metabolic process |
| macromolecule modification |
| protein modification process |
|
| Cellular Location
|
- Golgi apparatus membrane
- Single-pass type II membrane protein (Probable)
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:2 |
| Locus
| 2q24.3 |
| SNPs
| B3GALT1 |
| Gene Sequence
|
>981 bp
ATGGCTTCAAAGGTCTCCTGTTTGTATGTTTTGACAGTTGTGTGCTGGGCCAGCGCTCTC
TGGTACTTGAGTATAACTCGCCCTACTTCTTCTTACACTGGCTCCAAACCATTCAGCCAC
CTAACAGTTGCCAGGAAAAACTTCACCTTTGGCAACATAAGAACTCGACCTATCAACCCA
CATTCTTTTGAATTTCTTATCAACGAGCCCAATAAATGTGAGAAAAACATTCCTTTTCTT
GTTATCCTCATCAGCACCACTCACAAGGAATTTGATGCCCGTCAGGCAATCAGAGAGACG
TGGGGGGATGAGAACAACTTTAAGGGGATCAAGATAGCCACCCTGTTCCTCCTGGGCAAG
AATGCTGATCCTGTTCTCAATCAGATGGTGGAGCAAGAGAGCCAAATCTTCCATGATATC
ATCGTGGAGGACTTTATTGACTCCTACCATAACCTTACCCTCAAAACATTAATGGGGATG
AGATGGGTGGCCACTTTTTGTTCAAAAGCCAAGTATGTCATGAAAACAGACAGCGACATT
TTTGTAAACATGGACAATCTTATTTATAAATTACTGAAACCCTCCACCAAGCCACGAAGA
AGGTATTTTACTGGCTATGTCATTAATGGAGGACCGATTCGGGATGTCCGCAGTAAGTGG
TATATGCCCAGGGATTTGTACCCAGACAGTAACTACCCACCTTTCTGTTCGGGGACTGGC
TACATCTTTTCAGCCGATGTAGCTGAACTCATTTACAAGACCTCACTCCACACAAGGCTG
CTTCACCTTGAAGACGTATATGTGGGACTGTGTCTTCGAAAGCTGGGCATACATCCTTTC
CAGAACAGTGGCTTCAATCACTGGAAAATGGCCTACAGTTTGTGTAGGTATCGCCGAGTT
ATCACTGTGCATCAGATCTCTCCAGAAGAAATGCACAGAATCTGGAATGACATGTCAAGC
AAGAAACATCTCAGATGTTAG
|
| Protein Properties |
| Number of Residues
| 326 |
| Molecular Weight
| 37992.7 |
| Theoretical pI
| 9.65 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Beta-1,3-galactosyltransferase 1
MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVARKNFTFGNIRTRPINP
HSFEFLINEPNKCEKNIPFLVILISTTHKEFDARQAIRETWGDENNFKGIKIATLFLLGK
NADPVLNQMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCSKAKYVMKTDSDI
FVNMDNLIYKLLKPSTKPRRRYFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTG
YIFSADVAELIYKTSLHTRLLHLEDVYVGLCLRKLGIHPFQNSGFNHWKMAYSLCRYRRV
ITVHQISPEEMHRIWNDMSSKKHLRC
|
| External Links |
| GenBank ID Protein
| 7593005 |
| UniProtKB/Swiss-Prot ID
| Q9Y5Z6 |
| UniProtKB/Swiss-Prot Entry Name
| B3GT1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB041407 |
| GeneCard ID
| B3GALT1 |
| GenAtlas ID
| B3GALT1 |
| HGNC ID
| HGNC:916 |
| References |
| General References
| Not Available |