Cannabis Compound Database: Showing Protein Tubulin--tyrosine ligase (CDBP04040)

Identification Biological properties Gene properties Protein properties External links References XML Show 5 compounds

Identification

HMDB Protein ID

CDBP04040

Secondary Accession Numbers

Not Available

Name

Tubulin--tyrosine ligase

Description

Not Available

Synonyms

Gene Name

TTL

Protein Type

Enzyme

Biological Properties

General Function

Involved in catalytic activity

Specific Function

Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin (By similarity).

GO Classification

Biological Process
regulation of axon extension
cellular protein modification process
microtubule cytoskeleton organization
Function
catalytic activity
ligase activity
ligase activity, forming carbon-nitrogen bonds
acid-amino acid ligase activity
tubulin-tyrosine ligase activity
Molecular Function
tubulin-tyrosine ligase activity
ATP binding
Process
metabolic process
macromolecule metabolic process
biopolymer metabolism
biopolymer modification
protein modification
physiological process
metabolism
macromolecule metabolism
macromolecule modification
protein modification process

Cellular Location

Not Available

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

2q13

SNPs

TTL

Gene Sequence

>1134 bp
ATGTACACCTTCGTGGTACGCGATGAGAACAGCAGCGTCTACGCCGAGGTCTCCCGGCTG
CTCCTCGCCACCGGCCACTGGAAGAGGCTGCGGCGAGACAACCCCAGATTCAACCTGATG
CTGGGAGAGAGGAATCGGCTGCCCTTCGGGAGACTGGGTCACGAGCCCGGGCTGGTACAG
TTGGTGAATTACTACAGGGGTGCTGACAAACTGTGTCGCAAAGCTTCTTTAGTGAAGCTA
ATCAAGACAAGCCCTGAACTGGCTGAGTCCTGCACATGGTTCCCTGAATCTTATGTGATT
TATCCAACCAATCTCAAGACTCCAGTTGCTCCAGCACAGAATGGAATTCAGCCACCAATC
AGTAACTCAAGGACAGATGAAAGAGAATTCTTTCTCGCCTCTTATAACAGAAAGAAAGAG
GATGGAGAGGGCAACGTTTGGATTGCAAAGTCATCAGCCGGTGCCAAAGGTGAAGGCATT
CTCATCTCCTCAGAGGCTTCAGAGCTTCTCGATTTCATAGACAACCAGGGCCAAGTGCAC
GTGATCCAGAAATATCTTGAGCACCCTCTGCTGCTTGAGCCAGGTCATCGCAAGTTTGAC
ATCCGAAGCTGGGTCTTGGTGGATCATCAGTATAATATCTACCTCTATAGAGAGGGTGTG
CTTCGGACTGCTTCAGAACCATATCATGTTGATAATTTCCAAGACAAAACCTGCCATTTG
ACCAATCACTGCATTCAAAAAGAGTATTCAAAGAACTACGGGAAGTATGAAGAAGGAAAT
GAAATGTTCTTCAAGGAGTTCAATCAGTACCTAACAAGTGCTTTGAACATTACCCTAGAA
AGTAGTATCTTACTACAAATCAAACATATAATAAGGAACTGCCTCCTGAGCGTGGAGCCT
GCCATTAGCACCAAGCACCTCCCTTACCAGAGCTTCCAGCTCTTCGGCTTTGACTTCATG
GTCGATGAGGAGCTGAAGGTGTGGCTCATTGAGGTCAACGGTGCCCCTGCATGTGCTCAG
AAGCTCTATGCAGAACTGTGCCAAGGCATCGTGGACATAGCCATTTCCAGTGTCTTCCCA
CCCCCAGATGTGGAGCAACCTCAGACCCAGCCAGCTGCCTTCATCAAGCTGTGA

Protein Properties

Number of Residues

377

Molecular Weight

43211.94

Theoretical pI

6.744

Pfam Domain Function

TTL (PF03133 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Tubulin--tyrosine ligase
MYTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQ
LVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPI
SNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVH
VIQKYLEHPLLLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHL
TNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEP
AISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFP
PPDVEQPQTQPAAFIKL

External Links

GenBank ID Protein

40363527

UniProtKB/Swiss-Prot ID

Q8NG68

UniProtKB/Swiss-Prot Entry Name

TTL_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB071393

GeneCard ID