Showing Protein Three prime repair exonuclease 2 (CDBP04037)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP04037
Secondary Accession Numbers Not Available
Name Three prime repair exonuclease 2
Description Not Available
Synonyms
  1. 3'-5' exonuclease TREX2
Gene Name TREX2
Protein Type Enzyme
Biological Properties
General Function Involved in exonuclease activity
Specific Function Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair
GO Classification
Component
cell part
intracellular
Function
hydrolase activity, acting on ester bonds
binding
catalytic activity
hydrolase activity
exonuclease activity
nucleic acid binding
nuclease activity
Cellular Location
  1. Nucleus (Probable)
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs TREX2
Gene Sequence 
>840 bp
ATGGGGCGGGCAGGAAGCCCTCTCCCAAGATCGAGTTGGCCGAGGATGGATGATTGTGGC
AGCAGAAGCCGTTGCAGCCCCACGTTGTGCTCTAGTTTGAGGACTTGCTATCCCCGTGGG
AACATCACCATGTCCGAGGCACCCCGGGCCGAGACCTTTGTCTTCCTGGACCTGGAAGCC
ACTGGGCTCCCCAGTGTGGAGCCCGAGATTGCCGAGCTGTCCCTCTTTGCTGTCCACCGC
TCCTCCCTGGAGAACCCGGAGCACGACGAGTCTGGTGCCCTAGTATTGCCCCGGGTCCTG
GACAAGCTCACGCTGTGCATGTGCCCGGAGCGCCCCTTCACTGCCAAGGCCAGCGAGATC
ACCGGCCTGAGCAGTGAGGGCCTGGCGCGATGCCGGAAGGCTGGCTTTGATGGCGCCGTG
GTGCGGACGCTGCAGGCCTTCCTGAGCCGCCAGGCAGGGCCCATCTGCCTTGTGGCCCAC
AATGGCTTTGATTATGATTTCCCCCTGCTGTGTGCCGAGCTGCGGCGCCTGGGTGCCCGC
CTGCCCCGGGACACTGTCTGCCTGGACACGCTGCCGGCCCTGCGGGGCCTGGACCGCGCC
CACAGCCACGGCACCCGGGCCCGGGGCCGCCAGGGTTACAGCCTCGGCAGCCTCTTCCAC
CGCTACTTCCGGGCAGAGCCAAGCGCAGCCCACTCAGCCGAGGGCGACGTGCACACCCTG
CTCCTGATCTTCCTGCACCGCGCCGCAGAGCTGCTCGCCTGGGCCGATGAGCAGGCCCGT
GGGTGGGCCCACATCGAGCCCATGTACTTGCCGCCTGATGACCCCAGCCTGGAGGCCTGA
Protein Properties
Number of Residues 279
Molecular Weight 30620.4
Theoretical pI 6.83
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Three prime repair exonuclease 2
MGRAGSPLPRSSWPRMDDCGSRSRCSPTLCSSLRTCYPRGNITMSEAPRAETFVFLDLEA
TGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLPRVLDKLTLCMCPERPFTAKASEI
TGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPICLVAHNGFDYDFPLLCAELRRLGAR
LPRDTVCLDTLPALRGLDRAHSHGTRARGRQGYSLGSLFHRYFRAEPSAAHSAEGDVHTL
LLIFLHRAAELLAWADEQARGWAHIEPMYLPPDDPSLEA
GenBank ID Protein 12751319
UniProtKB/Swiss-Prot ID Q9BQ50
UniProtKB/Swiss-Prot Entry Name TREX2_HUMAN
PDB IDs
GenBank Gene ID AF319571
GeneCard ID TREX2
GenAtlas ID TREX2
HGNC ID HGNC:12270
References
General References Not Available