Showing Protein Putative nucleoside diphosphate kinase (CDBP03976)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 9 compounds
Identification
HMDB Protein ID CDBP03976
Secondary Accession Numbers Not Available
Name Putative nucleoside diphosphate kinase
Description Not Available
Synonyms
  1. NDK
  2. NDP kinase
Gene Name NME2P1
Protein Type Enzyme
Biological Properties
General Function Involved in nucleoside diphosphate kinase activity
Specific Function Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GO Classification
Function
adenyl ribonucleotide binding
atp binding
nucleoside diphosphate kinase activity
binding
catalytic activity
phosphotransferase activity, phosphate group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
Process
nucleoside phosphate metabolic process
nucleotide metabolic process
ctp biosynthetic process
pyrimidine nucleotide metabolic process
pyrimidine nucleoside triphosphate biosynthetic process
pyrimidine nucleotide biosynthetic process
pyrimidine ribonucleoside triphosphate biosynthetic process
utp biosynthetic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
gtp biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q24.31
SNPs NME2P1
Gene Sequence 
>414 bp
ATGCAGTGCGGCCTGGTGGGCAAGATCATCAAGCGCTTCGAGCAGAAGGGGTTCCGCCTC
GTGGCCATGAAGTTCCTCCCGGCCTCTGAAGAACACCTGAAGCAGCACTACATTGACCTG
AAGGACCGCCCATTCTTCCCTGGGCTGGTGAAGTACATGAACTCAGGGCCGGTCGTGGCC
ATGGTCTGGGAGGGGCTGAACGTCGTGAAGACAGGCCGAGTGATGCTTGGGGAGACCAAT
CCAGCAGATTCTAAGCCAGGCACCATTCGTGGGGACTTTTGCATTCAGGTTGGCAGGAAC
ATCATTCATGGCAGTGATTCAGTAAAAAGTGCTGAAAAAGAAATCAGCCTACGGTTTAAG
CCTGAAGAACTGGTTGACTACAAGTCTTGTGCTCATGACTGGGTCTATGAATAA
Protein Properties
Number of Residues 137
Molecular Weight 15529.0
Theoretical pI 8.83
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Putative nucleoside diphosphate kinase
MQCGLVGKIIKRFEQKGFRLVAMKFLPASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVA
MVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLRFK
PEELVDYKSCAHDWVYE
GenBank ID Protein 2935619
UniProtKB/Swiss-Prot ID O60361
UniProtKB/Swiss-Prot Entry Name NDK8_HUMAN
PDB IDs
GenBank Gene ID AC004263
GeneCard ID NME2P1
GenAtlas ID NME2P1
HGNC ID HGNC:31358
References
General References Not Available