| Identification |
|---|
| HMDB Protein ID
| CDBP03972 |
| Secondary Accession Numbers
| Not Available |
| Name
| Magnesium transporter MRS2 homolog, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- MRS2-like protein
|
| Gene Name
| MRS2 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in ion transport |
| Specific Function
| Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix.
|
| GO Classification
|
| Cellular Component |
| integral to membrane |
| mitochondrial inner membrane |
| Molecular Function |
| magnesium ion transmembrane transporter activity |
|
| Cellular Location
|
- Mitochondrion inner membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| 6p22.3-p22.1 |
| SNPs
| MRS2 |
| Gene Sequence
|
>1332 bp
ATGGAATGCCTGCGCAGTTTACCCTGCCTCCTGCCCCGCGCGATGAGACTTCCCCGGCGG
ACGCTGTGTGCCCTGGCCTTGGACGTGACCTCTGTGGGTCCTCCCGTTGCTGCCTGCGGC
CGCCGAGCCAACCTGATTGGAAGGAGCCGAGCGGCGCAGCTTTGCGGGCCCGACCGGCTC
CGCGTGGCAGGTGAAGTGCACCGGTTTAGAACCTCTGACGTCTCTCAAGCCACTTTAGCC
AGTGTAGCCCCAGTATTTACTGTGACAAAATTTGACAAACAGGGAAACGTTACTTCTTTT
GAAAGGAAGAAAACTGAATTATACCAAGAGTTAGGTCTTCAAGCCAGAGATTTGAGATTT
CAGCATGTAATGAGTATCACAGTCAGAAACAATAGGATTATCATGAGAATGGAGTATTTG
AAAGCTGTGATAACTCCAGAGTGTCTTCTGATATTAGATTATCGTAATTTAAACTTAGAG
CAATGGCTGTTCCGGGAACTCCCTTCACAGTTGTCTGGAGAGGGTCAACTCGTTACATAC
CCTTTACCTTTTGAGTTTAGAGCTATAGAAGCACTCCTGCAATATTGGATCAACACCCTT
CAGGGGAAACTTAGCATTTTGCAGCCACTGATCCTTGAGACCTTGGATGCTTTGGTGGAC
CCCAAACATTCTTCTGTAGACAGAAGCAAACTGCACATTTTACTACAGAATGGCAAAAGT
CTATCAGAGTTAGAAACAGATATTAAAATTTTCAAAGAGTCAATTTTGGAGATCTTGGAT
GAGGAAGAGTTGCTAGAAGAGCTCTGTGTATCAAAATGGAGTGACCCACAAGTCTTTGAA
AAGAGCAGTGCTGGGATTGACCATGCAGAAGAAATGGAGTTGCTGTTGGAAAACTACTAC
CGATTGGCTGACGATCTCTCCAATGCAGCTCGTGAGCTTAGGGTGCTGATTGATGATTCA
CAAAGTATTATTTTCATTAATCTGGACAGCCACCGAAACGTGATGATGAGGTTGAATCTA
CAGCTGACCATGGGAACCTTCTCTCTTTCGCTCTTTGGACTAATGGGAGTTGCTTTTGGA
ATGAATTTGGAATCTTCCCTTGAAGAGGACCATAGAATTTTTTGGCTGATTACAGGAATT
ATGTTCATGGGAAGTGGCCTCATCTGGAGGCGCCTGCTTTCATTCCTTGGACGACAGCTA
GAAGCTCCATTGCCTCCTATGATGGCTTCTTTACCTAAAAAGACTCTTCTGGCAGATAGA
AGCATGGAATTGAAAAATAGCCTCAGACTGGATGGACTTGGATCAGGAAGGAGCATCCTA
ACAAACCGTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 443 |
| Molecular Weight
| 50317.01 |
| Theoretical pI
| 6.877 |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Magnesium transporter MRS2 homolog, mitochondrial
MECLRSLPCLLPRAMRLPRRTLCALALDVTSVGPPVAACGRRANLIGRSRAAQLCGPDRL
RVAGEVHRFRTSDVSQATLASVAPVFTVTKFDKQGNVTSFERKKTELYQELGLQARDLRF
QHVMSITVRNNRIIMRMEYLKAVITPECLLILDYRNLNLEQWLFRELPSQLSGEGQLVTY
PLPFEFRAIEALLQYWINTLQGKLSILQPLILETLDALVDPKHSSVDRSKLHILLQNGKS
LSELETDIKIFKESILEILDEEELLEELCVSKWSDPQVFEKSSAGIDHAEEMELLLENYY
RLADDLSNAARELRVLIDDSQSIIFINLDSHRNVMMRLNLQLTMGTFSLSLFGLMGVAFG
MNLESSLEEDHRIFWLITGIMFMGSGLIWRRLLSFLGRQLEAPLPPMMASLPKKTLLADR
SMELKNSLRLDGLGSGRSILTNR
|
| External Links |
|---|
| GenBank ID Protein
| 9858855 |
| UniProtKB/Swiss-Prot ID
| Q9HD23 |
| UniProtKB/Swiss-Prot Entry Name
| MRS2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF288288 |
| GeneCard ID
| MRS2 |
| GenAtlas ID
| MRS2 |
| HGNC ID
| HGNC:13785 |
| References |
|---|
| General References
| Not Available |