| Identification |
|---|
| HMDB Protein ID
| CDBP03966 |
| Secondary Accession Numbers
| Not Available |
| Name
| Microtubule-associated serine/threonine-protein kinase 3 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| MAST3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein serine/threonine kinase activity |
| Specific Function
| ATP + a protein = ADP + a phosphoprotein |
| GO Classification
|
| Function |
| protein binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| magnesium ion binding |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19p13.11 |
| SNPs
| MAST3 |
| Gene Sequence
|
>3930 bp
ATGGACGAGTCGAGCCTCCTGCGGCGCCGCGGGCTCCAGAAGGAGCTGAGCCTGCCACGC
CGAGGACGTGGCTGCCGCAGCGGGAACCGCAAGAGCTTGGTGGTAGGAACGCCCTCCCCG
ACCCTCTCCCGGCCCCTGTCGCCATTGTCGGTCCCAACGGCAGGCAGCAGCCCCTTGGAT
AGTCCTCGGAATTTCTCGGCTGCCTCTGCCCTAAATTTCCCCTTTGCCCGGAGGGCAGAC
GGCAGAAGATGGTCCCTCGCGTCTCTCCCATCTTCCGGCTATGGAACCAACACACCCAGC
TCCACCCTCTCGTCAAGCTCATCCTCCCGGGAACGTCTCCACCAGCTTCCCTTCCAGCCG
ACGCCGGACGAGCTGCACTTCCTGTCCAAGCACTTCCGCAGCTCAGAGAATGTGCTTGAT
GAGGAAGGCGGCCGGTCACCCCGCCTCCGACCCCGCTCTCGCAGTCTCAGCCCGGGCCGT
GCAACGGGGACCTTCGACAATGAGATTGTCATGATGAATCACGTGTACCGGGAGAGGTTC
CCCAAGGCCACAGCACAGATGGAGGGCCGTCTGCAGGAGTTCCTGACGGCCTACGCGCCC
GGCGCCCGGCTGGCGCTGGCTGATGGCGTCTTGGGCTTCATCCACCACCAGATCGTCGAG
CTGGCCCGAGACTGCTTGGCCAAGTCTGGCGAGAACCTCGTCACCTCCCGCTACTTCCTA
GAGATGCAGGAGAAGCTGGAGCGGCTTCTGCAGGATGCCCATGAGCGTTCGGACAGTGAG
GAGGTCAGCTTCATCGTCCAGCTTGTCCGGAAACTGCTGATCATCATCTCACGGCCAGCT
CGGCTGCTGGAGTGTCTGGAGTTTGACCCTGAGGAATTTTACCACCTGCTGGAGGCGGCT
GAGGGCCATGCGCGGGAGGGCCAAGGCATTAAGACTGACCTTCCACAGTACATCATTGGG
CAGCTGGGCCTGGCCAAGGACCCCCTGGAGGAGATGGTGCCACTGAGTCACCTCGAAGAA
GAACAGCCCCCAGCACCTGAGTCCCCAGAGAGCCGCGCCCTGGTCGGCCAGTCACGGAGG
AAGCCATGCGAAAGCGACTTTGAGACCATCAAACTCATTAGCAACGGAGCCTATGGGGCC
GTCTACCTGGTGCGGCACCGTGACACACGGCAGCGCTTTGCCATCAAGAAGATCAACAAA
CAGAACTTGATCCTGCGTAACCAGATCCAGCAGGTCTTTGTGGAGCGTGACATTCTCACC
TTTGCCGAGAACCCCTTTGTGGTCAGCATGTTCTGCTCCTTTGAGACCCGGCGCCACCTA
TGTATGGTCATGGAATACGTGGAAGGCGGCGACTGCGCCACGCTCCTGAAGAACATGGGC
CCGCTGCCCGTGGACATGGCCCGCCTGTACTTCGCCGAGACGGTGTTGGCGCTGGAGTAC
CTGCATAACTATGGCATCGTGCACCGTGACCTCAAACCAGACAATCTGCTCATCACCTCG
CTTGGCCACATCAAGCTCACGGACTTCGGCCTGTCCAAGATCGGCCTCATGAGCATGGCC
ACCAACCTCTATGAGGGCCACATCGAGAAGGACGCCCGAGAGTTCATCGACAAGCAGGTG
TGTGGGACGCCGGAGTACATAGCCCCCGAGGTGATCTTCCGCCAGGGCTATGGGAAGCCA
GTGGACTGGTGGGCCATGGGCGTCGTCCTCTATGAGTTTCTGGTGGGCTGCGTGCCTTTC
TTTGGAGATACCCCCGAGGAACTCTTCGGTCAGGTGGTCAGCGATGAGATCATGTGGCCA
GAGGGAGATGAGGCCCTTCCAGCAGACGCCCAGGACCTCATCACCAGGTTGCTCCGGCAG
AGCCCGCTGGACCGTCTGGGCACTGGTGGCACCCACGAAGTGAAGCAGCACCCCTTTTTC
CTGGCCCTGGACTGGGCAGGGCTTCTCCGACACAAAGCCGAGTTCGTGCCCCAGCTCGAA
GCTGAGGATGATACCAGCTACTTTGACACACGTTCGGAACGTTACCGCCATCTGGGCTCC
GAGGACGACGAGACCAATGATGAAGAATCGTCCACAGAGATCCCCCAGTTCTCCTCCTGC
TCCCACCGGTTCAGCAAGGTCTACAGCAGCTCTGAGTTCCTGGCCGTCCAGCCCACTCCT
ACCTTCGCTGAAAGGAGCTTCAGTGAAGACCGGGAGGAGGGGTGGGAGCGCAGCGAAGTG
GACTATGGCCGCCGGCTGAGTGCTGACATCCGGCTGAGGTCCTGGACATCCTCTGGATCC
TCCTGTCAGTCATCTTCGTCCCAGCCCGAGCGGGGTCCCAGCCCATCTCTCCTGAATACC
ATCAGCCTGGACACAATGCCCAAGTTTGCCTTCTCATCAGAGGATGAGGGGGTAGGCCCA
GGCCCTGCAGGCCCCAAGAGGCCCGTCTTCATTCTAGGGGAGCCTGACCCCCCACCAGCG
GCCACCCCAGTGATGCCCAAGCCCTCGAGCCTTTCTGCCGACACAGCTGCTCTCAGCCAC
GCCCGCCTACGGAGCAATAGCATCGGCGCCCGACACTCCACACCAAGGCCTCTGGATGCC
GGCCGGGGCCGCCGCCTTGGGGGCCCAAGAGACCCAGCCCCTGAGAAGTCCAGAGCCTCC
TCCAGCGGTGGCAGTGGTGGCGGCAGTGGGGGCCGCGTGCCCAAGTCAGCCTCTGTCTCT
GCCCTGTCCCTCATCATCACGGCAGATGATGGCAGCGGCGGCCCCCTCATGAGCCCCCTT
TCCCCGCGCTCTCTGTCCTCGAACCCGTCGTCCCGTGACTCTTCGCCGAGCCGAGACCCG
TCCCCCGTGTGTGGCAGCCTGCGGCCCCCCATCGTTATCCACAGCTCTGGCAAGAAGTAC
GGCTTCAGCCTGCGGGCGATCCGCGTCTACATGGGTGATAGCGACGTCTACACTGTGCAC
CACGTCGTCTGGAGTGTGGAGGACGGAAGCCCCGCCCAGGAGGCGGGCCTGCGGGCTGGG
GACCTCATCACCCACATCAACGGGGAGTCAGTGCTGGGGCTGGTGCACATGGACGTCGTG
GAGCTGCTGCTGAAGAGCGGCAACAAGATATCCCTGCGGACCACAGCCCTGGAGAACACC
TCCATCAAGGTGGGCCCCGCCCGGAAGAATGTGGCCAAGGGCCGCATGGCACGCAGGAGC
AAGAGGAGCCGTCGGCGGGAGACCCAGGATCGGCGGAAGTCACTTTTCAAGAAGATCTCC
AAGCAGACCTCCGTGCTGCACACCAGCCGCAGCTTCTCCTCCGGACTCCACCACTCACTG
TCATCCAGTGAGAGCCTCCCCGGCTCGCCCACCCACAGCCTCTCCCCCAGCCCCACCACT
CCCTGCCGAAGCCCAGCCCCTGATGTCCCAGCAGATACCACTGCATCCCCACCCAGCGCA
TCCCCGAGCTCCAGCAGCCCCGCCTCCCCAGCTGCTGCTGGCCACACCCGCCCCAGCTCC
CTGCACGGCCTGGCTGCCAAGCTTGGGCCACCCCGCCCCAAGACTGGCCGCCGCAAGTCC
ACCAGCAGCATCCCGCCCTCCCCGCTGGCCTGCCCGCCCATCTCCGCGCCCCCACCCCGC
TCGCCCTCGCCCCTGCCCGGGCACCCGCCCGCACCTGCCCGATCCCCGCGGCTGCGCCGG
GGCCAGTCAGCTGACAAGCTGGGCACAGGGGAGCGGCTGGATGGGGAGGCGGGGCGGCGC
ACTCGTGGGCCAGAGGCCGAGCTCGTGGTCATGCGGCGGCTGCACCTGTCCGAGCGCCGA
GACTCCTTCAAGAAGCAGGAGGCCGTGCAGGAGGTTAGCTTCGATGAGCCGCAGGAGGAG
GCCACTGGGCTGCCCACCTCAGTGCCACAGATCGCCGTGGAGGGCGAGGAAGCCGTGCCA
GTAGCTCTCGGGCCCACCGGAAGAGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 1309 |
| Molecular Weight
| 143135.6 |
| Theoretical pI
| 8.13 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Microtubule-associated serine/threonine-protein kinase 3
MDESSLLRRRGLQKELSLPRRGRGCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGSSPLD
SPRNFSAASALNFPFARRADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPFQP
TPDELHFLSKHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERF
PKATAQMEGRLQEFLTAYAPGARLALADGVLGFIHHQIVELARDCLAKSGENLVTSRYFL
EMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAA
EGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLSHLEEEQPPAPESPESRALVGQSRR
KPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILT
FAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEY
LHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQV
CGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWP
EGDEALPADAQDLITRLLRQSPLDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLE
AEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTP
TFAERSFSEDREEGWERSEVDYGRRLSADIRLRSWTSSGSSCQSSSSQPERGPSPSLLNT
ISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSH
ARLRSNSIGARHSTPRPLDAGRGRRLGGPRDPAPEKSRASSSGGSGGGSGGRVPKSASVS
ALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKY
GFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVV
ELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKKIS
KQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSA
SPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPR
SPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHLSERR
DSFKKQEAVQEVSFDEPQEEATGLPTSVPQIAVEGEEAVPVALGPTGRD
|
| External Links |
|---|
| GenBank ID Protein
| 150170729 |
| UniProtKB/Swiss-Prot ID
| O60307 |
| UniProtKB/Swiss-Prot Entry Name
| MAST3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_015016.1 |
| GeneCard ID
| MAST3 |
| GenAtlas ID
| MAST3 |
| HGNC ID
| HGNC:19036 |
| References |
|---|
| General References
| Not Available |