Showing Protein Mitogen-activated protein kinase kinase kinase 15 (CDBP03959)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03959
Secondary Accession Numbers Not Available
Name Mitogen-activated protein kinase kinase kinase 15
Description Not Available
Synonyms
  1. MAPK/ERK kinase kinase 15
  2. MEK kinase 15
  3. MEKK 15
Gene Name MAP3K15
Protein Type Enzyme
Biological Properties
General Function Involved in protein kinase activity
Specific Function Component of a protein kinase signal transduction cascade
GO Classification
Function
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
Process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation
phosphorus metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs MAP3K15
Gene Sequence 
>3942 bp
ATGGAGAGCGGCGGTGGGAATGCTCCGGCCGGGGCCCTCGGGGCGGCGAGCGAGTCCCCT
CAGTGCCCGCCGCCGCCGGGGGTGGAGGGCGCGGCCGGGCCGGCGGAGCCCGACGGGGCG
GCGGAGGGCGCGGCAGGCGGCAGCGGCGAGGGCGAGAGTGGGGGCGGGCCGCGGCGGGCT
CTGCGGGCAGTATACGTGCGCAGTGAGAGCTCCCAGGGCGGCGCGGCCGGCGGCCCGGAG
GCTGGGGCGCGGCAGTGCCTGCTGCGGGCCTGCGAGGCCGAGGGCGCTCACCTCACCTCC
GTGCCCTTCGGGGAGCTGGACTTCGGGGAGACGGCCGTGCTCGACGCCTTCTACGACGCA
GATGTTGCTGTGGTAGACATGAGCGATGTCTCCAGACAGCCTTCCCTCTTCTACCATCTT
GGAGTCCGAGAAAGCTTTGACATGGCCAATAATGTGATCTTGTACCATGACACCGATGCC
GACACTGCTCTCTCTTTGAAGGACATGGTAACTCAAAAAAACACAGCATCCAGTGGAAAT
TATTATTTCATCCCATACATCGTGACACCGTGCGCTGATTATTTTTGCTGCGAGAGTGAT
GCCCAGAGACGAGCCTCCGAGTACATGCAGCCCAACTGGGACAACATCCTGGGCCCGCTG
TGCATGCCTTTGGTGGACAGGTTCATTAGCCTCCTTAAGGACATCCACGTGACCTCATGT
GTTTATTACAAAGAAACCTTGTTAAATGACATCCGGAAAGCCAGAGAGAAATACCAAGGT
GAGGAACTGGCGAAGGAGCTAGCTCGGATCAAGCTCCGCATGGATAATACTGAGGTTCTG
ACCTCAGACATCATCATTAACTTACTCCTGTCCTACCGTGATATCCAGGACTATGATGCG
ATGGTGAAGCTGGTGGAAACACTGGAGATGCTGCCTACGTGTGATTTGGCCGATCAGCAT
AACATTAAATTCCACTATGCGTTTGCACTGAATAGGAGAAACAGCACAGGTGACCGTGAG
AAGGCTCTGCAGATCATGCTCCAGGTTCTGCAGAGCTGTGATCACCCGGGCCCCGACATG
TTCTGCCTGTGTGGGAGGATCTACAAGGACATCTTCTTGGATTCAGACTGCAAAGATGAC
ACCAGCCGCGACAGCGCCATTGAGTGGTATCGCAAAGGGTTTGAACTCCAGTCATCCCTC
TATTCGGGAATTAATCTTGCAGTTTTGCTGATTGTTGCTGGACAACAATTTGAAACTTCC
TTGGAACTAAGGAAAATAGGTGTCCGGCTGAACAGTTTGTTGGGAAGAAAAGGGAGCTTG
GAGAAAATGAACAATTACTGGGATGTGGGTCAGTTCTTCAGCGTCAGCATGCTGGCCCAT
GATGTCGGGAAAGCCGTCCAGGCAGCAGAGAGGTTGTTCAAACTGAAACCTCCAGTCTGG
TACCTGCGATCATTAGTTCAGAACTTGTTACTAATTCGGCGCTTCAAGAAAACCATTATT
GAACACTCGCCCAGGCAAGAGCGGCTGAACTTCTGGTTAGATATAATTTTTGAGGCAACA
AATGAAGTCACTAATGGACTCAGATTTCCAGTTCTGGTCATAGAGCCAACCAAAGTGTAC
CAGCCTTCTTATGTTTCCATAAACAATGAAGCCGAGGAGAGAACAGTTTCTTTATGGCAT
GTCTCACCCACAGAAATGAAACAGATGCACGAATGGAATTTTACAGCCTCTTCCATAAAG
GGAATAAGCCTATCAAAGTTTGATGAAAGGTGTTGTTTTCTTTATGTCCATGATAATTCT
GATGACTTTCAAATCTACTTTTCCACCGAAGAGCAGTGCAGTAGATTTTTCTCTTTGGTC
AAAGAGATGATAACCAATACAGCAGGCAGTACGGTGGAGCTGGAGGGAGAGACCGATGGA
GACACCTTGGAGTATGAGTATGACCATGATGCAAATGGTGAGAGAGTTGTCTTGGGGAAA
GGCACGTATGGGATTGTGTATGCTGGCCGAGATCTGAGCAATCAAGTGCGAATAGCCATC
AAAGAAATCCCGGAGAGAGATAGCAGGTATTCTCAGCCTCTGCACGAGGAGATAGCCCTG
CACAAGTACCTTAAGCACCGCAATATCGTTCAGTACCTGGGCTCTGTTTCAGAGAACGGC
TACATTAAGATATTTATGGAGCAGGTGCCTGGAGGAAGCCTTTCTGCTCTTCTGCGATCC
AAATGGGGGCCGATGAAGGAACCGACAATCAAGTTTTACACCAAACAGATCCTGGAGGGC
CTTAAGTATCTTCATGAAAACCAGATCGTGCACAGAGACATAAAGGGCGATAATGTTCTG
GTGAACACCTACAGCGGAGTGGTGAAAATCTCCGATTTTGGAACCTCGAAACGTCTTGCG
GGTGTGAACCCCTGCACAGAGACTTTTACTGGCACCCTGCAGTACATGGCACCTGAGATA
ATTGACCAAGGGCCTCGCGGATATGGTGCCCCAGCCGATATCTGGTCCCTGGGCTGCACC
ATCATTGAGATGGCCACCAGCAAGCCTCCGTTCCATGAGCTTGGTGAGCCGCAGGCAGCC
ATGTTCAAAGTGGGCATGTTTAAGATCCACCCTGAGATTCCAGAAGCCCTTTCAGCTGAA
GCCCGAGCCTTCATTTTATCCTGTTTCGAGCCTGACCCCCACAAACGTGCCACCACTGCT
GAGCTACTGAGAGAGGGTTTCTTAAGGCAGGTGAACAAGGGCAAGAAGAACCGAATTGCC
TTCAAGCCCTCAGAAGGTCCCCGCGGTGTCGTCCTGGCCCTGCCCACACAGGGAGAGCCC
ATGGCCACCAGCAGCAGCGAGCACGGCTCTGTCTCCCCAGACTCCGACGCCCAGCCTGAC
GCACTCTTTGAGAGGACCCGGGCGCCCAGGCACCACCTTGGCCACCTCCTCAGTGTTCCA
GACGAGAGCTCAGCCTTGGAAGACCGGGGCTTGGCCTCGTCCCCGGAGGACAGGGACCAG
GGCCTCTTCCTGCTACGCAAGGACAGTGAGCGCCGTGCCATCCTGTACAAAATCCTCTGG
GAGGAGCAGAACCAGGTGGCTTCCAACCTGCAGGAGTGTGTGGCCCAGAGTTCCGAAGAG
TTGCATCTCTCAGTTGGACACATCAAGCAAATCATTGGGATCCTGAGGGACTTCATCCGC
TCCCCAGAGCACCGGGTGATGGCGACCACAATATCAAAGCTCAAGGTGGACCTGGACTTT
GACAGCTCGTCCATCAGTCAGATTCACCTGGTGCTGTTCGGATTTCAGGATGCCGTAAAT
AAAATTTTGAGGAACCACTTAATTAGGCCCCACTGGATGTTCGCGATGGACAACATCATC
CGCCGAGCGGTGCAGGCCGCGGTCACCATTCTCATCCCAGAGCTCCGAGCCCACTTTGAG
CCTACCTGTGAGACTGAAGGGGTAGATAAGGACATGGATGAAGCGGAAGAGGGCTATCCC
CCAGCCACCGGACCTGGCCAGGAGGCCCAGCCCCACCAGCAGCACCTGAGCCTCCAGCTG
GGTGAGCTCAGACAGGAGACCAACAGACTTTTGGAACACCTAGTTGAAAAAGAGAGAGAG
TACCAGAATCTTCTGCGGCAAACTCTAGAACAGAAAACTCAAGAATTGTATCACCTTCAG
TTAAAATTAAAATCGAATTGTATTACAGAGAACCCAGCAGGCCCCTACGGGCAGAGAACA
GATAAAGAGCTTATAGACTGGTTGCGGCTGCAAGGAGCTGATGCAAAGACAATTGAAAAG
ATTGTTGAAGAGGGTTATACACTTTCGGATATTCTTAATGAGATCACTAAGGAAGATCTA
AGATACCTTCGACTACGGGGTGGTCTCCTCTGCAGACTCTGGAGTGCGGTCTCCCAGTAC
AGAAGGGCTCAGGAGGCCTCAGAAACCAAAGACAAGGCTTGA
Protein Properties
Number of Residues 1313
Molecular Weight 147435.7
Theoretical pI 5.35
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Mitogen-activated protein kinase kinase kinase 15
MESGGGNAPAGALGAASESPQCPPPPGVEGAAGPAEPDGAAEGAAGGSGEGESGGGPRRA
LRAVYVRSESSQGGAAGGPEAGARQCLLRACEAEGAHLTSVPFGELDFGETAVLDAFYDA
DVAVVDMSDVSRQPSLFYHLGVRESFDMANNVILYHDTDADTALSLKDMVTQKNTASSGN
YYFIPYIVTPCADYFCCESDAQRRASEYMQPNWDNILGPLCMPLVDRFISLLKDIHVTSC
VYYKETLLNDIRKAREKYQGEELAKELARIKLRMDNTEVLTSDIIINLLLSYRDIQDYDA
MVKLVETLEMLPTCDLADQHNIKFHYAFALNRRNSTGDREKALQIMLQVLQSCDHPGPDM
FCLCGRIYKDIFLDSDCKDDTSRDSAIEWYRKGFELQSSLYSGINLAVLLIVAGQQFETS
LELRKIGVRLNSLLGRKGSLEKMNNYWDVGQFFSVSMLAHDVGKAVQAAERLFKLKPPVW
YLRSLVQNLLLIRRFKKTIIEHSPRQERLNFWLDIIFEATNEVTNGLRFPVLVIEPTKVY
QPSYVSINNEAEERTVSLWHVSPTEMKQMHEWNFTASSIKGISLSKFDERCCFLYVHDNS
DDFQIYFSTEEQCSRFFSLVKEMITNTAGSTVELEGETDGDTLEYEYDHDANGERVVLGK
GTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKYLKHRNIVQYLGSVSENG
YIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVL
VNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCT
IIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTA
ELLREGFLRQVNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVSPDSDAQPD
ALFERTRAPRHHLGHLLSVPDESSALEDRGLASSPEDRDQGLFLLRKDSERRAILYKILW
EEQNQVASNLQECVAQSSEELHLSVGHIKQIIGILRDFIRSPEHRVMATTISKLKVDLDF
DSSSISQIHLVLFGFQDAVNKILRNHLIRPHWMFAMDNIIRRAVQAAVTILIPELRAHFE
PTCETEGVDKDMDEAEEGYPPATGPGQEAQPHQQHLSLQLGELRQETNRLLEHLVEKERE
YQNLLRQTLEQKTQELYHLQLKLKSNCITENPAGPYGQRTDKELIDWLRLQGADAKTIEK
IVEEGYTLSDILNEITKEDLRYLRLRGGLLCRLWSAVSQYRRAQEASETKDKA
GenBank ID Protein 282847398
UniProtKB/Swiss-Prot ID Q6ZN16
UniProtKB/Swiss-Prot Entry Name M3K15_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001001671.3
GeneCard ID MAP3K15
GenAtlas ID MAP3K15
HGNC ID HGNC:31689
References
General References Not Available