Cannabis Compound Database: Showing Protein Inositol monophosphatase 3 (CDBP03942)

Identification Biological properties Gene properties Protein properties External links References XML Show 8 compounds

Identification

HMDB Protein ID

CDBP03942

Secondary Accession Numbers

Not Available

Name

Inositol monophosphatase 3

Description

Not Available

Synonyms

IMP 3
IMPase 3
Inositol monophosphatase domain-containing protein 1
Inositol-1(or 4)-monophosphatase 3
Myo-inositol monophosphatase A3
Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase
Golgi-resident PAP phosphatase
gPAPP

Gene Name

IMPAD1

Protein Type

Enzyme

Biological Properties

General Function

Involved in inositol or phosphatidylinositol phosphatase activity

Specific Function

May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation (By similarity).

GO Classification

Biological Process
post-embryonic development
chondroitin sulfate metabolic process
endochondral ossification
inositol biosynthetic process
phosphatidylinositol phosphorylation
chondrocyte development
embryonic digit morphogenesis
Cellular Component
Golgi apparatus
integral to membrane
Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
phosphatase activity
inositol or phosphatidylinositol phosphatase activity
Molecular Function
3'(2'),5'-bisphosphate nucleotidase activity
metal ion binding
inositol monophosphate 1-phosphatase activity
inositol monophosphate 3-phosphatase activity
inositol monophosphate 4-phosphatase activity
3'-nucleotidase activity

Cellular Location

Membrane
Single-pass membrane protein (Potential)

Pathways

Name	SMPDB/Pathwhiz	KEGG
myo-inositol biosynthesis	Not Available	Not Available
sulfur metabolism	Not Available
Phosphatidylinositol signaling system	Not Available

Gene Properties

Chromosome Location

Locus

8q12.1

SNPs

IMPAD1

Gene Sequence

>1080 bp
ATGGCCCCCATGGGCATCCGCCTTTCCCCACTGGGGGTGGCAGTGTTTTGTCTGCTGGGG
CTCGGCGTGCTCTACCACCTCTACTCGGGCTTCTTGGCCGGCCGCTTCAGCCTCTTCGGC
CTGGGCGGCGAGCCTGGCGGCGGCGCGGCGGGGCCCGCGGCCGCGGCCGATGGGGGCACC
GTGGACTTGCGCGAGATGCTGGCTGTGTCAGTGCTGGCCGCAGTCCGCGGCGGCGACGAG
GTGAGGCGCGTCCGCGAGAGCAACGTCCTCCACGAGAAGTCCAAGGGGAAGACGCGCGAG
GGAGCCGAGGACAAGATGACCAGCGGCGACGTGCTGTCCAACCGCAAGATGTTCTACCTG
CTCAAGACCGCCTTCCCCAGCGTCCAGATTAATACTGAGGAACACGTGGATGCAGCTGAT
CAGGAGGTTATCTTGTGGGATCATAAGATTCCTGAGGATATCCTAAAGGAAGTAACTACT
CCTAAAGAGGTACCAGCAGAAAGTGTTACTGTCTGGATTGACCCACTTGATGCTACACAG
GAATATACAGAGGATCTTCGAAAGTACGTCACTACTATGGTGTGTGTGGCTGTAAATGGT
AAACCCATGCTAGGAGTTATACATAAGCCATTTTCCGAATATACAGCTTGGGCAATGGTA
GATGGTGGTTCAAATGTGAAAGCCCGCTCTTCCTACAATGAGAAGACCCCAAGGATCGTT
GTGTCTCGTTCCCATTCAGGGATGGTCAAACAGGTCGCTCTTCAGACTTTTGGAAACCAG
ACTACAATTATCCCAGCTGGTGGTGCTGGTTATAAAGTTTTAGCACTTTTGGATGTGCCT
GATAAGAGTCAAGAAAAAGCTGATTTATACATCCATGTGACATACATCAAAAAGTGGGAT
ATATGTGCTGGTAATGCCATCTTAAAAGCCCTAGGGGGGCATATGACTACCCTGAGTGGT
GAAGAAATCAGTTACACTGGTTCAGACGGCATTGAAGGGGGACTCCTTGCTAGCATCAGA
ATGAACCACCAGGCCCTGGTCAGAAAACTCCCAGATCTAGAAAAGACAGGACATAAATGA

Protein Properties

Number of Residues

359

Molecular Weight

38681.15

Theoretical pI

6.864

Pfam Domain Function

Inositol_P (PF00459 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Inositol monophosphatase 3
MAPMGIRLSPLGVAVFCLLGLGVLYHLYSGFLAGRFSLFGLGGEPGGGAAGPAAAADGGT
VDLREMLAVSVLAAVRGGDEVRRVRESNVLHEKSKGKTREGAEDKMTSGDVLSNRKMFYL
LKTAFPSVQINTEEHVDAADQEVILWDHKIPEDILKEVTTPKEVPAESVTVWIDPLDATQ
EYTEDLRKYVTTMVCVAVNGKPMLGVIHKPFSEYTAWAMVDGGSNVKARSSYNEKTPRIV
VSRSHSGMVKQVALQTFGNQTTIIPAGGAGYKVLALLDVPDKSQEKADLYIHVTYIKKWD
ICAGNAILKALGGHMTTLSGEEISYTGSDGIEGGLLASIRMNHQALVRKLPDLEKTGHK

External Links

GenBank ID Protein

7020510

UniProtKB/Swiss-Prot ID

Q9NX62

UniProtKB/Swiss-Prot Entry Name

IMPA3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AK000428

GeneCard ID