Showing Protein Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (CDBP03887)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03887
Secondary Accession Numbers Not Available
Name Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
Description Not Available
Synonyms
  1. NifU-like N-terminal domain-containing protein
  2. NifU-like protein
Gene Name ISCU
Protein Type Metal Binding
Biological Properties
General Function Involved in iron ion binding
Specific Function Involved in the assembly or repair of the [Fe-S] clusters present in iron-sulfur proteins. Binds iron
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
transition metal ion binding
metal cluster binding
iron-sulfur cluster binding
iron ion binding
protein binding
Process
iron-sulfur cluster assembly
metabolic process
biosynthetic process
cellular biosynthetic process
cofactor biosynthetic process
metallo-sulfur cluster assembly
Cellular Location
  1. Nucleus
  2. Isoform 2:Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q24.1
SNPs ISCU
Gene Sequence 
>504 bp
ATGGCGGCGGCTGGGGCTTTCCGTCTGAGGCGGGCGGCATCGGCTCTGCTGCTGCGGAGC
CCCCGCCTGCCCGCCCGGGAGCTGTCGGCCCCGGCCCGACTCTATCACAAGAAGGTTGTT
GATCATTATGAAAATCCTAGAAACGTGGGGTCCCTTGACAAGACATCTAAAAATGTTGGA
ACTGGACTGGTGGGGGCTCCAGCATGTGGTGACGTAATGAAATTACAGATTCAAGTGGAT
GAAAAGGGGAAGATTGTGGATGCTAGGTTTAAAACATTTGGCTGTGGTTCCGCAATTGCC
TCCAGCTCATTAGCCACTGAATGGGTGAAAGGAAAGACGGTGGAGGAAGCCTTGACTATC
AAAAACACAGATATCGCCAAGGAGCTCTGCCTTCCTCCCGTGAAACTGCACTGCTCCATG
CTGGCTGAAGATGCAATCAAGGCCGCCCTGGCTGATTACAAATTGAAACAAGAACCCAAA
AAAGGAGAGGCAGAGAAGAAATGA
Protein Properties
Number of Residues 167
Molecular Weight 17936.7
Theoretical pI 10.13
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
MAAAGAGRLRRVASALLLRSPRLPARELSAPARLYHKKVVDHYENPRNVGSLDKTSKNVG
TGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTI
KNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK
GenBank ID Protein 56699456
UniProtKB/Swiss-Prot ID Q9H1K1
UniProtKB/Swiss-Prot Entry Name ISCU_HUMAN
PDB IDs
GenBank Gene ID NM_213595.2
GeneCard ID ISCU
GenAtlas ID ISCU
HGNC ID HGNC:29882
References
General References Not Available