Showing Protein Nuclear factor erythroid 2-related factor 1 (CDBP03871)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03871
Secondary Accession Numbers Not Available
Name Nuclear factor erythroid 2-related factor 1
Description Not Available
Synonyms
  1. Locus control region-factor 1
  2. NF-E2-related factor 1
  3. NFE2-related factor 1
  4. Nuclear factor, erythroid derived 2, like 1
  5. TCF-11
  6. Transcription factor 11
  7. Transcription factor HBZ17
  8. Transcription factor LCR-F1
Gene Name NFE2L1
Protein Type Transcription Factor
Biological Properties
General Function Involved in sequence-specific DNA binding transcription factor activity
Specific Function Activates erythroid-specific, globin gene expression
GO Classification
Function
binding
protein binding
nucleic acid binding
dna binding
protein dimerization activity
sequence-specific dna binding
sequence-specific dna binding transcription factor activity
Process
regulation of transcription
regulation of transcription, dna-dependent
biological regulation
regulation of biological process
regulation of metabolic process
regulation of macromolecule metabolic process
regulation of gene expression
Cellular Location
  1. Nucleus
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 17q21.3
SNPs NFE2L1
Gene Sequence 
>2319 bp
ATGCTTTCTCTGAAGAAATACTTAACGGAAGGACTTCTCCAGTTCACCATTCTGCTGAGT
TTGATTGGGGTACGGGTGGACGTGGATACTTACCTGACCTCACAGCTTCCCCCACTCCGG
GAGATCATCCTGGGGCCCAGTTCTGCCTATACTCAGACCCAGTTCCACAACCTGAGGAAT
ACCTTGGATGGCTATGGTATCCACCCCAAGAGCATAGACCTGGACAATTACTTCACTGCC
CGGCGGCTCCTCAGTCAGGTGAGGGCCCTGGACAGGTTCCAGGTGCCAACCACTGAGGTA
AATGCCTGGCTGGTTCACCGAGACCCAGAGGGGTCTGTCTCTGGCAGTCAGCCCAACTCA
GGCCTCGCCCTCGAGAGTTCCAGTGGCCTCCAAGATGTGACAGGCCCAGACAACGGGGTG
CGAGAAAGCGAAACGGAGCAGGGATTCGGTGAAGATTTGGAGGATTTGGGGGCTGTAGCC
CCCCCAGTCAGTGGAGACTTAACCAAAGAGGACATAGATCTGATTGACATCCTTTGGCGA
CAGGATATTGATCTGGGGGCTGGGCGTGAGGTTTTTGACTATAGTCACCGCCAGAAGGAG
CAGGATGTGGAGAAGGAGCTGCGAGATGGAGGCGAGCAGGACACCTGGGCAGGCGAGGGC
GCGGAAGCTCTGGCACGGAACCTGCTAGTGGATGGAGAGACTGGGGAGAGCTTCCCTGCA
CAGGTGCCTAGTGGGGAGGACCAGACGGCCCTGTCCCTGGAAGAGTGCCTTAGGCTGCTG
GAAGCCACCTGCCCCTTTGGGGAGAATGCTGAGTTTCCAGCAGACATTTCCAGCATAACA
GAAGCAGTGCCTAGTGAGAGTGAGCCCCCTGCTCTTCAAAACAACCTCTTGTCTCCTCTT
CTGACCGGGACAGAGTCACCATTTGATTTGGAACAGCAGTGGCAAGATCTCATGTCCATC
ATGGAAATGCAGGCCATGGAAGTGAACACATCAGCAAGTGAAATCCTGTACAGTGCCCCT
CCTGGAGACCCACTGAGCACCAACTACAGCCTTGCCCCCAACACTCCCATCAATCAGAAT
GTCAGCCTGCATCAGGCGTCCCTGGGGGGCTGCAGCCAGGACTTCTTACTCTTCAGCCCC
GAGGTGGAAAGCCTGCCTGTGGCCAGTAGCTCCACGCTGCTCCCGTTGGCCCCCAGCAAT
TCTACCAGCCTCAACTCCACCTTCGGCTCCACCAACCTGACAGGGCTCTTCTTTCCACCC
CAGCTCAATGGCACAGCCAATGACACAGCAGGCCCAGAGCTGCCTGACCCTTTGGGGGGT
CTGTTAGATGAAGCTATGTTGGATGAGATCAGCCTTATGGACCTGGCCATTGAAGAAGGC
TTTAACCCTGTGCAGGCCTCCCAGCTGGAGGAGGAATTTGACTCTGACTCAGGCCTTTCC
TTAGACTCGAGCCATAGCCCTTCTTCCCTAAGCAGCTCTGAAGGCAGTTCTTCCTCTTCT
TCCTCCTCCTCTTCCTCTTCTTCCTCTGCTTCTTCCTCTGCCTCTTCCTCCTTTTCTGAG
GAAGGTGCGGTTGGCTACAGCTCTGACTCTGAGACCCTGGATCTGGAAGAGGCCGAGGGT
GCTGTGGGCTACCAGCCTGAGTATTCCAAGTTCTGCCGCATGAGCTACCAGGATCCAGCT
CAGCTCTCATGCCTGCCCTACCTGGAGCACGTGGGCCACAACCACACATACAACATGGCA
CCCAGTGCCCTGGACTCAGCCGACCTGCCACCACCCAGTGCCCTCAAGAAAGGCAGCAAG
GAGAAGCAGGCTGACTTCCTGGACAAGCAGATGAGCCGGGATGAGCACCGAGCCCGAGCC
ATGAAGATCCCTTTCACCAATGACAAAATCATCAACCTGCCTGTGGAGGAGTTCAATGAA
CTGCTGTCCAAATACCAGTTGAGTGAAGCCCAGCTGAGCCTCATCCGAGACATCCGGCGC
CGGGGCAAGAACAAGATGGCGGCGCAGAACTGCCGCAAGCGCAAGCTGGACACCATCCTG
AATCTGGAGCGTGATGTGGAGGACCTGCAGCGTGACAAAGCCCGGCTGCTGCGGGAGAAA
GTGGAGTTCCTGCGCTCCCTGCGACAGATGAAGCAGAAGGTCCAGAGCCTGTACCAGGAG
GTGTTTGGGCGGCTGCGAGATGAGAACGGACGACCCTACTCGCCCAGTCAGTATGCGCTC
CAGTACGCCGGGGACGGCAGTGTCCTCCTCATCCCCCGCACGATGGCCGACCAGCAGGCC
CGGCGGCAGGAGAGGAAGCCAAAGGACCGGAGAAAGTGA
Protein Properties
Number of Residues 772
Molecular Weight 84702.8
Theoretical pI 4.25
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Nuclear factor erythroid 2-related factor 1
MLSLKKYLTEGLLQFTILLSLIGVRVDVDTYLTSQLPPLREIILGPSSAYTQTQFHNLRN
TLDGYGIHPKSIDLDNYFTARRLLSQVRALDRFQVPTTEVNAWLVHRDPEGSVSGSQPNS
GLALESSSGLQDVTGPDNGVRESETEQGFGEDLEDLGAVAPPVSGDLTKEDIDLIDILWR
QDIDLGAGREVFDYSHRQKEQDVEKELRDGGEQDTWAGEGAEALARNLLVDGETGESFPA
QVPSGEDQTALSLEECLRLLEATCPFGENAEFPADISSITEAVPSESEPPALQNNLLSPL
LTGTESPFDLEQQWQDLMSIMEMQAMEVNTSASEILYSAPPGDPLSTNYSLAPNTPINQN
VSLHQASLGGCSQDFLLFSPEVESLPVASSSTLLPLAPSNSTSLNSTFGSTNLTGLFFPP
QLNGTANDTAGPELPDPLGGLLDEAMLDEISLMDLAIEEGFNPVQASQLEEEFDSDSGLS
LDSSHSPSSLSSSEGSSSSSSSSSSSSSSASSSASSSFSEEGAVGYSSDSETLDLEEAEG
AVGYQPEYSKFCRMSYQDPAQLSCLPYLEHVGHNHTYNMAPSALDSADLPPPSALKKGSK
EKQADFLDKQMSRDEHRARAMKIPFTNDKIINLPVEEFNELLSKYQLSEAQLSLIRDIRR
RGKNKMAAQNCRKRKLDTILNLERDVEDLQRDKARLLREKVEFLRSLRQMKQKVQSLYQE
VFGRLRDENGRPYSPSQYALQYAGDGSVLLIPRTMADQQARRQERKPKDRRK
GenBank ID Protein 4505379
UniProtKB/Swiss-Prot ID Q14494
UniProtKB/Swiss-Prot Entry Name NF2L1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_003204.2
GeneCard ID NFE2L1
GenAtlas ID NFE2L1
HGNC ID HGNC:7781
References
General References Not Available