Showing Protein Heme transporter HRG1 (CDBP03867)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03867
Secondary Accession Numbers Not Available
Name Heme transporter HRG1
Description Not Available
Synonyms
  1. HRG-1
  2. Heme-responsive gene 1 protein homolog
  3. Solute carrier family 48 member 1
  4. hHRG-1
Gene Name SLC48A1
Protein Type Transporter
Biological Properties
General Function Involved in transport
Specific Function Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
GO Classification
Cellular Component
endosome membrane
lysosomal membrane
integral to membrane
Molecular Function
heme transporter activity
Cellular Location
  1. Endosome membrane
  2. Lysosome membrane
  3. Multi-pass membrane protein
  4. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location 12
Locus 12q13.11
SNPs SLC48A1
Gene Sequence 
>441 bp
ATGGCCCCGTCCAGGCTGCAGCTCGGCCTCCGCGCCGCCTACTCCGGCATCAGCTCCGTG
GCCGGCTTCTCCATCTTCCTCGTCTGGACGGTGGTCTACCGACAGCCGGGGACCGCGGCC
ATGGGAGGGCTCGCAGGGGTGCTGGCACTGTGGGTCCTGGTGACGCACGTGATGTACATG
CAAGATTATTGGAGGACCTGGCTCAAGGGGCTGCGCGGCTTCTTCTTCGTGGGCGTCCTC
TTCTCGGCCGTCTCCATCGCTGCCTTCTGCACCTTCCTCGTGCTGGCCATCACCCGGCAT
CAGAGCCTCACAGACCCCACCAGCTACTACCTCTCCAGCGTCTGGAGCTTCATTTCCTTC
AAGTGGGCCTTCCTGCTCAGCCTCTATGCCCACCGCTACCGGGCTGACTTTGCTGACATC
AGCATCCTCAGCGATTTCTGA
Protein Properties
Number of Residues 146
Molecular Weight 16419.045
Theoretical pI 9.644
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Heme transporter HRG1
MAPSRLQLGLRAAYSGISSVAGFSIFLVWTVVYRQPGTAAMGGLAGVLALWVLVTHVMYM
QDYWRTWLKGLRGFFFVGVLFSAVSIAAFCTFLVLAITRHQSLTDPTSYYLSSVWSFISF
KWAFLLSLYAHRYRADFADISILSDF
GenBank ID Protein 209862796
UniProtKB/Swiss-Prot ID Q6P1K1
UniProtKB/Swiss-Prot Entry Name HRG1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_017842.2
GeneCard ID SLC48A1
GenAtlas ID SLC48A1
HGNC ID HGNC:26035
References
General References Not Available