| Identification |
|---|
| HMDB Protein ID
| CDBP03865 |
| Secondary Accession Numbers
| Not Available |
| Name
| Heme-binding protein 2 |
| Description
| Not Available |
| Synonyms
|
- PP23
- Placental protein 23
- Protein SOUL
|
| Gene Name
| HEBP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Cytoplasm
- Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:6 |
| Locus
| 6q24 |
| SNPs
| HEBP2 |
| Gene Sequence
|
>618 bp
ATGGCCGAGCCGCTCCAGCCAGACCCCGGGGCGGCCGAGGACGCGGCGGCCCAAGCTGTG
GAGACGCCGGGCTGGAAGGCCCCGGAGGACGCCGGCCCCCAGCCCGGAAGTTATGAGATC
CGACACTATGGACCAGCCAAGTGGGTCAGCACGTCCGTGGAGTCTATGGACTGGGATTCA
GCCATCCAGACGGGCTTTACGAAACTGAACAGCTACATTCAAGGCAAAAACGAGAAAGAG
ATGAAAATAAAGATGACAGCTCCAGTGACAAGCTACGTGGAGCCTGGTTCAGGTCCTTTT
AGTGAGTCTACCATTACCATTTCCCTGTATATTCCCTCTGAACAGCAATTTGATCCACCC
AGGCCTTTAGAGTCAGATGTCTTCATTGAAGATAGAGCCGAAATGACTGTGTTTGTACGG
TCTTTCGATGGATTTTCTAGTGCCCAAAAGAATCAAGAACAACTTTTGACATTAGCAAGC
ATTTTAAGGGAAGATGGAAAAGTTTTCGATGAGAAGGTTTACTACACTGCAGGCTACAAC
AGTCCTGTCAAATTGCTTAATAGAAATAATGAAGTGTGGTTGATTCAAAAAAATGAACCC
ACCAAAGAAAACGAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 205 |
| Molecular Weight
| 22875.3 |
| Theoretical pI
| 4.27 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Heme-binding protein 2
MAEPLQPDPGAAEDAAAQAVETPGWKAPEDAGPQPGSYEIRHYGPAKWVSTSVESMDWDS
AIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPGSGPFSESTITISLYIPSEQQFDPP
RPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLLTLASILREDGKVFDEKVYYTAGYN
SPVKLLNRNNEVWLIQKNEPTKENE
|
| External Links |
|---|
| GenBank ID Protein
| 4886910 |
| UniProtKB/Swiss-Prot ID
| Q9Y5Z4 |
| UniProtKB/Swiss-Prot Entry Name
| HEBP2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF117616 |
| GeneCard ID
| HEBP2 |
| GenAtlas ID
| HEBP2 |
| HGNC ID
| HGNC:15716 |
| References |
|---|
| General References
| Not Available |