| Identification |
|---|
| HMDB Protein ID
| CDBP03796 |
| Secondary Accession Numbers
| Not Available |
| Name
| Secretion-regulating guanine nucleotide exchange factor |
| Description
| Not Available |
| Synonyms
|
- Deafness locus-associated putative guanine nucleotide exchange factor
- DelGEF
- Guanine nucleotide exchange factor-related protein
|
| Gene Name
| SERGEF |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Nucleus
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 11p14.3 |
| SNPs
| SERGEF |
| Gene Sequence
|
>1377 bp
ATGGAGCGCGAGCCCAGCGCCTCGGAGGCCGCCCCCGCGGCGGCCGCGCTCTTCGCCTGG
GGTGCAAATAGCTATGGGCAACTTGGCCTCGGCCATAAGGAAGATGTGCTGTTGCCCCAG
CAACTGAATGACTTCTGTAAACCCAGGAGTGTCAGGAGGATCACAGGAGGAGGGGGCCAC
TCTGCAGTTGTCACAGATGGAGGAGACCTCTTTGTTTGTGGCCTGAACAAAGATGGGCAA
CTGGGGCTTGGTCACACAGAGGATATCCCATATTTTACCCCCTGCAAATCCCTCTTTGGC
TGTCCCATCCAACAGGTGGCCTGTGGCTGGGATTTTACGATTATGCTCACAGAAAATGGT
CAAGTTCTATCATGTGGATCCAACTCCTTTGGCCAGTTAGGAGTTCCTCATGGACCTCGA
AGATGTGTGGTTCCCCAGGCCATTGAGCTCCATAAAGAGAAGGTTGTTTGTATTGCTGCT
GGACTGAGGCATGCAGTAGCTGCTACAGCGAGTGGCATCGTGTTCCAGTGGGGGACTGGT
TTGGCATCATGTGGACGACGGTTGTGCCCTGGGCAGACTCTTCCATTGTTTTTCACAGCA
AAGGAACCAAGCAGAGTGACAGGTCTAGAGAATTCTAAAGCAATGTGTGTTCTTGCTGGC
TCAGACCACTCAGCTTCATTAACAGATGCAGGAGAGGTGTATGTTTGGGGAAGCAACAAG
CATGGGCAACTGGCTAATGAGGCTGCTTTCCTTCCTGTGCCCCAGAAAATAGAAGCACAT
TGTTTCCAGAATGAAAAGGTCACTGCCATCTGGAGTGGATGGACACACCTGGTTGCCCAG
ACAGAAACTGGCAAGATGTTTACCTGGGGCCGAGCAGACTATGGTCAGCTAGGGAGGAAG
TTGGAGACTTATGAAGGCTGGAAACTAGAAAAGCAAGATTCATTTCTCCCCTGTTCAAGA
CCACCGAACAGCATGCCTTCATCTCCGCATTGCTTAACTGGAGCAACTGAGGTCTCTTGT
GGCTCAGAGCATAATTTGGCAATAATTGGTGGAGTGTGTTACTCTTGGGGCTGGAATGAG
CATGGCATGTGCGGAGATGGCACTGAAGCCAACGTCTGGGCCCCAAAGCCGGTGCAGGCT
CTGCTGTCATCGTCAGGACTCCTTGTGGGCTGTGGGGCTGGCCACTCCTTGGCCCTCTGC
CAGCTGCCAGCTCACCCTGCATTGGTCCAGGACCCCAAGGTCACCTACCTTTCCCCAGAT
GCCATCGAGGACACTGAATCTCAGAAAGCCATGGACAAAGAGAGAAACTGGAAGGAAAGA
CAATCAGAAACTTCAACCCAAAGCCAATCTGACTGGTCCAGAAATGGGGGACTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 458 |
| Molecular Weight
| 48981.0 |
| Theoretical pI
| 6.44 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Secretion-regulating guanine nucleotide exchange factor
MEREPSASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGH
SAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENG
QVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQWGTG
LASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNK
HGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRK
LETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIGGVCYSWGWNE
HGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHSLALCQLPAHPALVQDPKVTYLSPD
AIEDTESQKAMDKERNWKERQSETSTQSQSDWSRNGGL
|
| External Links |
|---|
| GenBank ID Protein
| 6434157 |
| UniProtKB/Swiss-Prot ID
| Q9UGK8 |
| UniProtKB/Swiss-Prot Entry Name
| SRGEF_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ243950 |
| GeneCard ID
| SERGEF |
| GenAtlas ID
| SERGEF |
| HGNC ID
| HGNC:17499 |
| References |
|---|
| General References
| Not Available |