| Identification |
|---|
| HMDB Protein ID
| CDBP03782 |
| Secondary Accession Numbers
| Not Available |
| Name
| Rhotekin |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RTKN |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transduction |
| Specific Function
| Mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2p13.1 |
| SNPs
| RTKN |
| Gene Sequence
|
>1692 bp
ATGTTCTCCCGAAACCACCGGAGCCGGGTCACCGTGGCCAGGGGCTCCGCCCTGGAGATG
GAGTTCAAACGCGGCCGCTTCCGACTCAGCCTCTTCAGCGACCTGCCCGAGGACACGGAG
TTGCAGAGGAAGCTAGACCATGAGATCCGGATGAGGGAAGGGGCCTGTAAGCTGCTGGCA
GCCTGCTCCCAGCGAGAGCAGGCTCTGGAGGCCACCAAGAGCCTGCTAGTGTGCAACAGC
CGCATCCTCAGCTACATGGGCGAGCTGCAGCGGCGCAAGGAGGCGCAGGTGCTGGGGAAG
ACAAGCCGGCGGCCTTCTGACAGTGGCCCGCCCGCTGAGCGCTCCCCCTGCCGCGGCCGG
GTCTGCATCTCTGACCTCCGGATTCCACTCATGTGGAAGGACACAGAATATTTCAAGAAC
AAAGGTGACTTGCACCGCTGGGCTGTGTTCCTGCTGCTGCAGCTGGGGGAACACATCCAG
GACACAGAGATGATCCTAGTGGACAGGACCCTCACAGACATCTCCTTTCAGAGCAATGTG
CTCTTCGCTGAGGCGGGGCCAGACTTTGAACTGCGGTTAGAGCTGTATGGGGCCTGTGTG
GAAGAAGAGGGGGCCCTGACTGGCGGCCCCAAGAGGCTTGCCACCAAACTCAGCAGCTCC
CTGGGCCGCTCCTCAGGGAGGCGTGTCCGGGCATCGCTGGACAGTGCTGGGGGTTCAGGG
AGCAGTCCCATCTTGCTCCCCACCCCAGTTGTTGGTGGTCCTCGTTACCACCTCTTGGCT
CACACCACACTCACCCTGGCAGCAGTGCAAGATGGATTCCGCACACATGACCTCACCCTT
GCCAGTCATGAGGAGAACCCTGCCTGGCTGCCCCTTTATGGTAGCGTGTGTTGCCGTCTG
GCAGCTCAGCCTCTCTGCATGACTCAGCCCACTGCAAGTGGTACCCTCAGGGTGCAGCAA
GCTGGGGAGATGCAGAACTGGGCACAAGTGCATGGAGTTCTGAAAGGCACAAACCTCTTC
TGTTACCGGCAACCTGAGGATGCAGACACTGGGGAAGAGCCGCTGCTTACTATTGCTGTC
AACAAGGAGACTCGAGTCCGGGCAGGGGAGCTGGACCAGGCTCTAGGACGGCCCTTCACC
CTAAGCATCAGTAACCAGTATGGGGATGATGAGGTGACACACACCCTTCAGACAGAAAGT
CGGGAAGCACTGCAGAGCTGGATGGAGGCTCTGTGGCAGCTTTTCTTTGACATGAGCCAA
TGGAAGCAGTGCTGTGATGAAATCATGAAAATTGAAACTCCTGCTCCCCGGAAACCACCC
CAAGCACTGGCAAAGCAGGGGTCCTTGTACCATGAGATGGCTATTGAGCCGCTGGATGAC
ATCGCAGCGGTGACAGACATCCTGACCCAGCGGGAGGGCGCAAGGCTGGAGACACCCCCA
CCCTGGCTGGCAATGTTTACAGACCAGCCTGCCCTGCCTAACCCCTGCTCGCCTGCCTCA
GTGGCCCCAGCCCCAGACTGGACCCACCCCCTGCCCTGGGGGAGACCCCGAACCTTTTCC
CTGGATGCTGTCCCCCCAGACCACTCCCCTAGGGCTCGCTCGGTTGCCCCCCTCCCACCT
CAGCGATCCCCACGGACCAGAGGCCTCTGCAGCAAAGGCCAACCTCGCACTTGGCTCCAG
TCACCAGTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 563 |
| Molecular Weight
| 62666.8 |
| Theoretical pI
| 7.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Rhotekin
MFSRNHRSRVTVARGSALEMEFKRGRFRLSLFSDLPEDTELQRKLDHEIRMREGACKLLA
ACSQREQALEATKSLLVCNSRILSYMGELQRRKEAQVLGKTSRRPSDSGPPAERSPCRGR
VCISDLRIPLMWKDTEYFKNKGDLHRWAVFLLLQLGEHIQDTEMILVDRTLTDISFQSNV
LFAEAGPDFELRLELYGACVEEEGALTGGPKRLATKLSSSLGRSSGRRVRASLDSAGGSG
SSPILLPTPVVGGPRYHLLAHTTLTLAAVQDGFRTHDLTLASHEENPAWLPLYGSVCCRL
AAQPLCMTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEEPLLTIAV
NKETRVRAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREALQSWMEALWQLFFDMSQ
WKQCCDEIMKIETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPP
PWLAMFTDQPALPNPCSPASVAPAPDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPP
QRSPRTRGLCSKGQPRTWLQSPV
|
| External Links |
|---|
| GenBank ID Protein
| 62739179 |
| UniProtKB/Swiss-Prot ID
| Q9BST9 |
| UniProtKB/Swiss-Prot Entry Name
| RTKN_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001015055.1 |
| GeneCard ID
| RTKN |
| GenAtlas ID
| RTKN |
| HGNC ID
| HGNC:10466 |
| References |
|---|
| General References
| Not Available |