| Identification |
|---|
| HMDB Protein ID
| CDBP03770 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ras and Rab interactor 3 |
| Description
| Not Available |
| Synonyms
|
- Ras interaction/interference protein 3
|
| Gene Name
| RIN3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transduction |
| Specific Function
| Potential Ras effector protein. May function as a guanine nucleotide exchange (GEF), by exchanging bound GDP for free GTP |
| GO Classification
|
| Function |
| binding |
| protein binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
|
| Cellular Location
|
- Cytoplasm
- Cytoplasmic vesicle
- Early endosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q32.12 |
| SNPs
| RIN3 |
| Gene Sequence
|
>2958 bp
ATGATCCGACACGCCGGGGCGCCCGCGCGCGGGGACCCCACGGGTCCGGTTCCAGTTGTT
GGCAAAGGAGAGGAAGAGGAAGAGGAAGATGGCATGCGGCTTTGTCTGCCAGCCAACCCG
AAAAACTGCCTTCCTCACCGCCGGGGCATCAGCATCCTGGAGAAGCTCATCAAAACATGC
CCGGTGTGGCTGCAGCTGAGTCTGGGCCAGGCAGAGGTGGCCAGGATCCTGCACCGGGTG
GTGGCTGGGATGTTCCTGGTTCGCCGGGACAGCAGCTCGAAGCAGCTGGTGCTCTGTGTC
CACTTTCCTTCTCTGAACGAAAGCTCGGCCGAGGTGCTCGAATACACCATTAAGGAAGAA
AAGTCGATATTGTACCTGGAAGGCTCGGCTCTTGTGTTTGAGGACATCTTCAGATTGATT
GCGTTCTACTGTGTCAGTAGAGACTTACTGCCCTTCACACTGCGGCTACCCCAGGCCATC
CTTGAGGCCAGCAGCTTCACGGACCTTGAGACCATCGCCAACCTGGGTCTGGGTTTCTGG
GACTCCTCGCTGAATCCTCCACAAGAAAGAGGGAAGCCAGCAGAGCCCCCAAGAGACCGG
GCCCCCGGATTCCCCCTAGTCTCCAGCCTCAGGCCCACAGCCCATGACGCAAACTGTGCC
TGTGAAATCGAGCTGTCGGTAGGAAATGACCGCCTGTGGTTTGTGAATCCTATTTTCATC
GAGGACTGCAGCAGCGCCCTGCCCACCGACCAGCCACCTCTTGGAAATTGCCCTGCACGC
CCTTTGCCGCCCACCTCTGATGCCACCTCACCCACCTCCAGGTGGGCCCCACGCCGCCCA
CCACCCCCTCCCCCAGTGCTGCCCCTGCAGCCCTGCAGCCCAGCCCAGCCCCCTGTGCTC
CCTGCTCTTGCCCCCGCCCCTGCCTGTCCTTTGCCCACCTCTCCCCCAGTGCCTGCCCCC
CACGTCACACCCCATGCCCCAGGTCCCCCAGACCATCCGAACCAGCCGCCCATGATGACC
TGCGAGAGACTCCCATGCCCCACTGCAGGCCTGGGCCCCCTCAGGGAGGAAGCGATGAAG
CCAGGGGCAGCCTCCAGTCCCTTGCAGCAGGTCCCCGCCCCGCCACTGCCTGCGAAGAAG
AACCTTCCCACTGCCCCTCCCAGACGCCGCGTTTCCGAGAGGGTGTCCTTAGAAGACCAA
AGTCCGGGGATGGCGGCAGAGGGGGACCAGCTCAGCCTGCCTCCCCAAGGGACCTCAGAC
GGCCCTGAGGACACGCCCCGGGAGAGCACGGAGCAAGGCCAGGACACAGAGGTGAAAGCC
AGCGATCCTCACAGCATGCCAGAGCTGCCCAGGACAGCCAAACAACCCCCAGTCCCGCCC
CCCAGGAAAAAACGGATCTCTCGACAACTGGCCTCGACCCTCCCAGCTCCCTTAGAGAAC
GCTGAGCTCTGCACACAGGCGATGGCCTTGGAGACACCCACGCCGGGTCCACCCAGAGAG
GGCCAAAGCCCTGCTTCTCAGGCTGGGACTCAGCACCCTCCTGCCCAGGCCACTGCCCAT
TCCCAGAGCTCTCCAGAGTTCAAGGGCTCCCTGGCCTCCCTCTCAGACAGCTTGGGGGTG
TCTGTCATGGCCACCGACCAGGACTCCTACTCCACCAGCAGCACGGAGGAGGAGCTGGAG
CAGTTCAGCAGCCCCAGCGTGAAGAAGAAGCCCTCCATGATCCTGGGCAAGGCTCGGCAC
CGGCTGAGCTTTGCCAGTTTCAGCAGCATGTTCCACGCTTTCCTCTCCAACAACCGCAAG
CTGTACAAGAAGGTGGTGGAGCTGGCGCAGGACAAGGGCTCGTACTTTGGCAGCCTGGTG
CAGGACTACAAGGTGTACAGCCTGGAGATGATGGCGCGCCAGACCTCCAGCACGGAGATG
CTGCAGGAGATTCGCACCATGATGACCCAGCTCAAGAGCTACCTGCTGCAGAGCACCGAG
CTCAAGGCCCTGGTGGACCCCGCCCTGCACTCCGAGGAGGAGCTCGAAGCAATTGTAGAG
TCTGCCTTGTACAAATGTGTCCTGAAGCCCCTGAAGGAAGCCATCAACTCATGCCTGCAT
CAGATCCACAGCAAGGATGGTTCGCTGCAGCAGCTCAAGGAGAACCAGTTAGTGATCCTG
GCCACCACCACCACTGACCTAGGTGTGACCACCAGCGTGCCGGAGGTGCCCATGATGGAG
AAGATCCTGCAGAAGTTCACCAGCATGCACAAGGCCTACTCACCTGAGAAGAAGATCTCC
ATCCTGCTCAAGACCTGCAAACTCATCTACGACTCCATGGCCCTCGGCAACCCAGGGAAG
CCCTATGGGGCGGATGACTTCCTGCCTGTGCTCATGTATGTGCTGGCCCGCAGCAACCTC
ACGGAGATGCTTCTCAATGTGGAGTACATGATGGAGCTCATGGACCCCGCCCTGCAGCTG
GGGGAGGGTTCCTACTATCTGACCACCACCTACGGGGCCCTGGAGCACATCAAGAGCTAC
GACAAGATCACGGTGACCCGGCAGCTGAGTGTGGAGGTGCAGGACTCCATCCACCGCTGG
GAGCGCCGGCGTACTCTCAACAAGGCCCGGGCCTCCCGCTCCTCCGTACAGGACTTCATC
TGCGTGTCGTACCTGGAGCCCGAGCAGCAGGCGCGGACGCTGGCGTCGCGGGCGGACACC
CAGGCCCAGGCGCTGTGCGCGCAGTGCGCGGAGAAGTTCGCGGTGGAGCGGCCGCAGGCG
CACCGGCTGTTCGTGCTGGTGGACGGGCGCTGCTTCCAGCTGGCGGACGACGCGCTGCCG
CACTGCATCAAGGGCTACCTGCTGCGCAGCGAGCCCAAGCGCGACTTCCACTTTGTCTAC
CGGCCCCTGGACGGTGGTGGCGGCGGCGGCGGCGGGAGCCCGCCCTGCCTGGTGGTGCGG
GAGCCCAACTTCCTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 985 |
| Molecular Weight
| 107852.4 |
| Theoretical pI
| 6.58 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ras and Rab interactor 3
MIRHAGAPARGDPTGPVPVVGKGEEEEEEDGMRLCLPANPKNCLPHRRGISILEKLIKTC
PVWLQLSLGQAEVARILHRVVAGMFLVRRDSSSKQLVLCVHFPSLNESSAEVLEYTIKEE
KSILYLEGSALVFEDIFRLIAFYCVSRDLLPFTLRLPQAILEASSFTDLETIANLGLGFW
DSSLNPPQERGKPAEPPRDRAPGFPLVSSLRPTAHDANCACEIELSVGNDRLWFVNPIFI
EDCSSALPTDQPPLGNCPARPLPPTSDATSPTSRWAPRRPPPPPPVLPLQPCSPAQPPVL
PALAPAPACPLPTSPPVPAPHVTPHAPGPPDHPNQPPMMTCERLPCPTAGLGPLREEAMK
PGAASSPLQQVPAPPLPAKKNLPTAPPRRRVSERVSLEDQSPGMAAEGDQLSLPPQGTSD
GPEDTPRESTEQGQDTEVKASDPHSMPELPRTAKQPPVPPPRKKRISRQLASTLPAPLEN
AELCTQAMALETPTPGPPREGQSPASQAGTQHPPAQATAHSQSSPEFKGSLASLSDSLGV
SVMATDQDSYSTSSTEEELEQFSSPSVKKKPSMILGKARHRLSFASFSSMFHAFLSNNRK
LYKKVVELAQDKGSYFGSLVQDYKVYSLEMMARQTSSTEMLQEIRTMMTQLKSYLLQSTE
LKALVDPALHSEEELEAIVESALYKCVLKPLKEAINSCLHQIHSKDGSLQQLKENQLVIL
ATTTTDLGVTTSVPEVPMMEKILQKFTSMHKAYSPEKKISILLKTCKLIYDSMALGNPGK
PYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPALQLGEGSYYLTTTYGALEHIKSY
DKITVTRQLSVEVQDSIHRWERRRTLNKARASRSSVQDFICVSYLEPEQQARTLASRADT
QAQALCAQCAEKFAVERPQAHRLFVLVDGRCFQLADDALPHCIKGYLLRSEPKRDFHFVY
RPLDGGGGGGGGSPPCLVVREPNFL
|
| External Links |
|---|
| GenBank ID Protein
| 40353729 |
| UniProtKB/Swiss-Prot ID
| Q8TB24 |
| UniProtKB/Swiss-Prot Entry Name
| RIN3_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_024832.3 |
| GeneCard ID
| RIN3 |
| GenAtlas ID
| RIN3 |
| HGNC ID
| HGNC:18751 |
| References |
|---|
| General References
| Not Available |