| Identification |
| HMDB Protein ID
| CDBP03767 |
| Secondary Accession Numbers
| Not Available |
| Name
| Regulating synaptic membrane exocytosis protein 2 |
| Description
| Not Available |
| Synonyms
|
- RIM 2
- Rab-3-interacting molecule 2
- Rab-3-interacting protein 3
|
| Gene Name
| RIMS2 |
| Protein Type
| Metal Binding |
| Biological Properties |
| General Function
| Involved in protein binding |
| Specific Function
| Rab effector involved in exocytosis. May act as scaffold protein |
| GO Classification
|
| Function |
| small gtpase regulator activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
| enzyme regulator activity |
| rab gtpase binding |
| protein binding |
| nucleoside-triphosphatase regulator activity |
| gtpase regulator activity |
| Process |
| intracellular protein transport |
| establishment of localization |
| transport |
| protein transport |
|
| Cellular Location
|
- Cell membrane
- Peripheral membrane protein
- Peripheral membrane protein
- Cell junction
- Cell junction
- synapse
- synapse
- presynaptic cell membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:8 |
| Locus
| 8q22.3 |
| SNPs
| RIMS2 |
| Gene Sequence
|
Not Available
|
| Protein Properties |
| Number of Residues
| 1411 |
| Molecular Weight
| 160401.6 |
| Theoretical pI
| 9.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Regulating synaptic membrane exocytosis protein 2
MSAPVGPRGRLAPIPAASQPPLQPEMPDLSHLTEEERKIILAVMDRQKKKVKEEHKPQLT
QWFPFSGITELVNNVLQPQQKQQNEKEPQTKLHQQFEMYKEQVKKMGEESQQQQEQKGDA
PTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCRKQQEILTKSGA
WFYNSGSNTPQQPDQKVLRGLRNEEAPQEKKPKLHEQTQFQGPSGDLSVPAVEKSRSHGL
TRQHSIKNGSGVKHHIASDIASDRKRSPSVSRDQNRRYDQREEREEYSQYATSDTAMPRS
PSDYADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYERQRREEEY
QSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVSLANADLEDSRISMLRMD
RPSRQRSISERRAAMENQRSYSMERTREAQGPSSYAQRTTNHSPPTPRRSPLPIDRPDLR
RTDSLRKQHHLDPSSAVRKTKREKMETMLRNDSLSSDQSESVRPPPPKPHKSKKGGKMRQ
ISLSSSEEELASTPEYTSCDDVEIESESVSEKGDSQKGKRKTSEQAVLSDSNTRSERQKE
MMYFGGHSLEEDLEWSEPQIKDSGVDTCSSTTLNEEHSHSDKHPVTWQPSKDGDRLIGRI
LLNKRLKDGSVPRDSGAMLGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVL
EWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSSFESQ
KMDRPSISVTSPMSPGMLRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLPSREDGRP
RNPYVKIYFLPDRSDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLEITLWDQAR
VREEESEFLGEILIELETALLDDEPHWYKLQTHDVSSLPLPHPSPYMPRRQLHGESPTRR
LQRSKRISDSEVSDYDCDDGIGVVSDYRHDGRDLQSSTLSVPEQVMSSNHCSPSGSPHRV
DVIGRTRSWSPSVPPPQSRNVEQGLRGTRTMTGHYNTISRMDRHRVMDDHYSPDRDRDCE
AADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAPPSPALSRSHP
RTGSVQTSPSSTPVAGRRGRQLPQLPPKGTLDRKAGGKKLRSTVQRSTETGLAVEMRNWM
TRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGPAQLVGRQTLATPAMGD
IQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLLDNGVCIAKKKTKVARKTLE
PLYQQLLSFEESPQGKVLQIIVWGDYGRMDHKSFMGVAQILLDELELSNMVIGWFKLFPP
SSLVDPTLAPLTRRASQSSLESSTGPSYSRS
|
| External Links |
| GenBank ID Protein
| 154354981 |
| UniProtKB/Swiss-Prot ID
| Q9UQ26 |
| UniProtKB/Swiss-Prot Entry Name
| RIMS2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| RIMS2 |
| GenAtlas ID
| RIMS2 |
| HGNC ID
| HGNC:17283 |
| References |
| General References
| Not Available |