Showing Protein Rho-related GTP-binding protein RhoF (CDBP03763)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03763
Secondary Accession Numbers Not Available
Name Rho-related GTP-binding protein RhoF
Description Not Available
Synonyms
  1. Rho family GTPase Rif
  2. Rho in filopodia
Gene Name RHOF
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology
GO Classification
Component
intracellular
cell part
Function
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Cytoplasm
  4. cytoskeleton
  5. Cytoplasmic side (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q24.31
SNPs RHOF
Gene Sequence 
>636 bp
ATGGATGCCCCCGGGGCCCTGGCCCAGACCGCCGCCCCCGGTCCGGGCAGGAAGGAGCTG
AAGATCGTGATCGTGGGCGACGGCGGCTGCGGCAAGACCTCGCTGCTCATGGTGTACAGC
CAGGGCTCCTTCCCCGAGCACTACGCCCCATCGGTGTTCGAGAAGTACACGGCCAGCGTG
ACCGTTGGCAGCAAGGAGGTGACCCTGAACCTCTACGACACGGCCGGGCAAGAAGACTAT
GACCGGCTGCGGCCCCTGTCCTACCAGAACACCCACCTCGTGCTCATCTGCTATGACGTC
ATGAATCCCACCAGCTACGACAACGTCCTCATCAAGTGGTTCCCTGAGGTCACGCATTTC
TGCCGCGGGATCCCCATGGTGCTCATCGGCTGCAAGACAGACCTGAGGAAGGACAAGGAG
CAGCTGCGGAAGCTCCGGGCCGCCCAGCTGGAGCCCATCACCTACATGCAGGGCCTGAGC
GCCTGCGAACAGATCCGAGCTGCTCTCTACCTGGAATGTTCCGCCAAGTTTCGGGAGAAT
GTGGAGGACGTCTTCCGGGAGGCCGCCAAGGTGGCTCTCAGCGCTCTGAAGAAGGCGCAA
CGGCAGAAGAAGCGCCGGCTCTGCCTGCTGCTCTGA
Protein Properties
Number of Residues 211
Molecular Weight 23625.2
Theoretical pI 8.82
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Rho-related GTP-binding protein RhoF
MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
VEDVFREAAKVALSALKKAQRQKKRRLCLLL
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9HBH0
UniProtKB/Swiss-Prot Entry Name RHOF_HUMAN
PDB IDs Not Available
GenBank Gene ID AF239923
GeneCard ID RHOF
GenAtlas ID RHOF
HGNC ID HGNC:15703
References
General References Not Available