| Identification |
| HMDB Protein ID
| CDBP03749 |
| Secondary Accession Numbers
| Not Available |
| Name
| GTP-binding protein REM 2 |
| Description
| Not Available |
| Synonyms
|
- Rad and Gem-like GTP-binding protein 2
|
| Gene Name
| REM2 |
| Protein Type
| Transcription Factor |
| Biological Properties |
| General Function
| Involved in GTP binding |
| Specific Function
| Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| membrane |
| Function |
| transcription factor binding |
| gtpase activity |
| nucleoside-triphosphatase activity |
| purine nucleotide binding |
| hydrolase activity, acting on acid anhydrides |
| binding |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| nucleotide binding |
| pyrophosphatase activity |
| catalytic activity |
| hydrolase activity |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein binding |
| Process |
| small gtpase mediated signal transduction |
| biological regulation |
| regulation of biological process |
| regulation of metabolic process |
| regulation of macromolecule metabolic process |
| regulation of gene expression |
| regulation of transcription |
| regulation of transcription, dna-dependent |
| regulation of cellular process |
| signal transduction |
| intracellular signal transduction |
|
| Cellular Location
|
- Cell membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q11.2 |
| SNPs
| REM2 |
| Gene Sequence
|
>1023 bp
ATGCACACGGACCTGGACACAGACATGGACATGGACACAGAAACCACAGCACTCTGCCCC
TCTGGCAGCCGCCGGGCCTCCCCTCCAGGGACGCCCACACCAGAAGCAGATGCCACGCTA
CTAAAGAAGTCAGAGAAACTGTTGGCAGAGTTGGACCGGAGCGGGTTACCCTCTGCCCCT
GGGGCCCCCAGACGAAGAGGCAGTATGCCTGTCCCCTACAAGCACCAGCTCCGGCGGGCC
CAGGCTGTAGATGAACTTGACTGGCCACCTCAGGCCTCATCCTCTGGCTCGTCTGACTCC
TTGGGCTCAGGGGAGGCAGCCCCTGCTCAAAAGGATGGCATCTTCAAGGTCATGCTAGTG
GGGGAGAGCGGCGTGGGCAAGAGCACCCTAGCAGGCACTTTTGGTGGTCTCCAGGGAGAC
AGTGCTCACGAACCGGAGAACCCAGAGGATACCTATGAGAGACGCATCATGGTGGATAAG
GAGGAAGTGACTCTAGTCGTTTATGACATCTGGGAACAGGGGGATGCAGGAGGGTGGCTG
CGGGACCACTGCCTTCAGACCGGAGACGCCTTTCTCATCGTCTTCTCAGTCACCGACCGA
CGGAGTTTCTCCAAAGTTCCAGAGACCCTACTTCGGCTCCGGGCTGGGAGGCCGCACCAC
GACCTACCCGTTATCCTCGTTGGAAACAAGAGCGACTTGGCCCGCTCCCGGGAGGTATCA
CTGGAGGAGGGCCGCCACCTGGCCGGGACGCTGAGCTGCAAGCACATCGAGACGTCGGCC
GCACTGCACCACAACACGAGGGAGCTCTTCGAGGGCGCGGTGCGCCAGATCCGGCTGCGG
CGGGGCCGAAACCACGCCGGAGGCCAGAGGCCCGATCCGGGCAGCCCCGAGGGCCCTGCG
CCACCTGCACGCCGCGAGAGCCTCACCAAGAAAGCCAAGAGGTTCCTCGCCAACCTGGTG
CCGCGCAACGCCAAGTTCTTCAAGCAGCGCTCCAGGTCGTGTCACGACCTCTCGGTGCTC
TGA
|
| Protein Properties |
| Number of Residues
| 340 |
| Molecular Weight
| 37138.4 |
| Theoretical pI
| 8.36 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>GTP-binding protein REM 2
MHTDLDTDMDMDTETTALCPSGSRRASPPGTPTPEADATLLKKSEKLLAELDRSGLPSAP
GAPRRRGSMPVPYKHQLRRAQAVDELDWPPQASSSGSSDSLGSGEAAPAQKDGIFKVMLV
GESGVGKSTLAGTFGGLQGDSAHEPENPEDTYERRIMVDKEEVTLVVYDIWEQGDAGGWL
RDHCLQTGDAFLIVFSVTDRRSFSKVPETLLRLRAGRPHHDLPVILVGNKSDLARSREVS
LEEGRHLAGTLSCKHIETSAALHHNTRELFEGAVRQIRLRRGRNHAGGQRPDPGSPEGPA
PPARRESLTKKAKRFLANLVPRNAKFFKQRSRSCHDLSVL
|
| External Links |
| GenBank ID Protein
| 21755736 |
| UniProtKB/Swiss-Prot ID
| Q8IYK8 |
| UniProtKB/Swiss-Prot Entry Name
| REM2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK096283 |
| GeneCard ID
| REM2 |
| GenAtlas ID
| REM2 |
| HGNC ID
| HGNC:20248 |
| References |
| General References
| Not Available |