Showing Protein GTPase NRas (CDBP03739)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP03739
Secondary Accession Numbers Not Available
Name GTPase NRas
Description Not Available
Synonyms
  1. Transforming protein N-Ras
Gene Name NRAS
Protein Type Enzyme
Biological Properties
General Function Involved in GTP binding
Specific Function Ras proteins bind GDP/GTP and possess intrinsic GTPase activity
GO Classification
Component
intracellular
membrane
cell part
Function
purine nucleotide binding
binding
nucleotide binding
catalytic activity
hydrolase activity
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
gtpase activity
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
Process
regulation of cellular process
signal transduction
intracellular signal transduction
small gtpase mediated signal transduction
biological regulation
regulation of biological process
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. Lipid-anchor
  4. Golgi apparatus membrane
  5. Cytoplasmic side
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1p13.2
SNPs NRAS
Gene Sequence 
>570 bp
ATGACTGAGTACAAACTGGTGGTGGTTGGAGCAGGTGGTGTTGGGAAAAGCGCACTGACA
ATCCAGCTAATCCAGAACCACTTTGTAGATGAATATGATCCCACCATAGAGGATTCTTAC
AGAAAACAAGTGGTTATAGATGGTGAAACCTGTTTGTTGGACATACTGGATACAGCTGGA
CAAGAAGAGTACAGTGCCATGAGAGACCAATACATGAGGACAGGCGAAGGCTTCCTCTGT
GTATTTGCCATCAATAATAGCAAGTCATTTGCGGATATTAACCTCTACAGGGAGCAGATT
AAGCGAGTAAAAGACTCGGATGATGTACCTATGGTGCTAGTGGGAAACAAGTGTGATTTG
CCAACAAGGACAGTTGATACAAAACAAGCCCACGAACTGGCCAAGAGTTACGGGATTCCA
TTCATTGAAACCTCAGCCAAGACCAGACAGGGTGTTGAAGATGCTTTTTACACACTGGTA
AGAGAAATACGCCAGTACCGAATGAAAAAACTCAACAGCAGTGATGATGGGACTCAGGGT
TGTATGGGATTGCCATGTGTGGTGATGTAA
Protein Properties
Number of Residues 189
Molecular Weight 21229.0
Theoretical pI 4.78
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>GTPase NRas
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG
CMGLPCVVM
GenBank ID Protein 20147731
UniProtKB/Swiss-Prot ID P01111
UniProtKB/Swiss-Prot Entry Name RASN_HUMAN
PDB IDs Not Available
GenBank Gene ID AF493919
GeneCard ID NRAS
GenAtlas ID NRAS
HGNC ID HGNC:7989
References
General References Not Available