| Identification |
|---|
| HMDB Protein ID
| CDBP03736 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ras association domain-containing protein 2 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RASSF2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in signal transduction |
| Specific Function
| Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest |
| GO Classification
|
| Function |
| binding |
| protein binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 20p13 |
| SNPs
| RASSF2 |
| Gene Sequence
|
>981 bp
ATGGACTACAGCCACCAAACGTCCCTAGTCCCATGTGGACAAGATAAATACATTTCCAAA
AATGAACTTCTCTTGCATCTGAAGACCTACAACTTGTACTATGAAGGCCAGAATTTACAG
CTCCGGCACCGGGAGGAAGAAGACGAGTTCATTGTGGAGGGGCTCCTGAACATCTCCTGG
GGCCTGCGCCGGCCCATTCGCCTGCAGATGCAGGATGACAACGAACGCATTCGACCCCCT
CCATCCTCCTCCTCCTGGCACTCTGGCTGTAACCTGGGGGCTCAGGGAACCACTCTGAAG
CCCCTGACTGTGCCCAAAGTTCAGATCTCAGAGGTGGATGCCCCGCCGGAGGGTGACCAG
ATGCCAAGCTCCACAGACTCCAGGGGCCTGAAGCCCCTGCAGGAGGACACCCCACAGCTG
ATGCGCACACGCAGTGATGTTGGGGTGCGTCGCCGTGGCAATGTGAGGACGCCTAGTGAC
CAGCGGCGAATCAGATGCCACCGCTTCTCCATCAACGGCCATTTCTACAACCATAAGACA
TCCGTGTTCACACCAGCCTATGGCTCTGTCACCAACGTCCGCATCAACAGCACCATGACC
ACCCCACAGGTCCTGAAGCTGCTGCTCAACAAATTTAAGATTGAGAATTCAGCAGAGGAG
TTTGCCTTGTACGTGGTCCATACGAGTGGTGAGAAACAGAAGCTGAAGGCCACCGATTAC
CCGCTGATTGCCCGAATCCTCCAGGGCCCATGTGAGCAGATCTCCCAAGTGTTCCTAATG
GAGAAGGACCAGGTGGAGGAAGTCACCTACGACGTGGCCCAGTATATAAAGTTCGAGATG
CCGGTACTTAAAAGCTTCATTCAGAAGCTCCAGGAGGAAGAAGATCGGGAAGTAAAGAAG
CTGATGCGCAAGTACACCGTGCTCCGGCTAATGATTCGACAGAGGCTGGAGGAGATAGCC
GAGACCCCAGCAACAATCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 326 |
| Molecular Weight
| 37789.9 |
| Theoretical pI
| 9.17 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ras association domain-containing protein 2
MDYSHQTSLVPCGQDKYISKNELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISW
GLRRPIRLQMQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQ
MPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSDQRRIRRHRFSINGHFYNHKT
SVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKATDY
PLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVKK
LMRKYTVLRLMIRQRLEEIAETPATI
|
| External Links |
|---|
| GenBank ID Protein
| 62896859 |
| UniProtKB/Swiss-Prot ID
| P50749 |
| UniProtKB/Swiss-Prot Entry Name
| RASF2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK222650 |
| GeneCard ID
| RASSF2 |
| GenAtlas ID
| RASSF2 |
| HGNC ID
| HGNC:9883 |
| References |
|---|
| General References
| Not Available |