| Identification |
| HMDB Protein ID
| CDBP03735 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ras and EF-hand domain-containing protein |
| Description
| Not Available |
| Synonyms
|
- Ras-related protein Rab-45
|
| Gene Name
| RASEF |
| Protein Type
| Metal Binding |
| Biological Properties |
| General Function
| Involved in calcium ion binding |
| Specific Function
| Binds predominantly GDP, and also GTP |
| GO Classification
|
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| calcium ion binding |
| Process |
| transport |
| protein transport |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| intracellular signal transduction |
| small gtpase mediated signal transduction |
| establishment of localization |
|
| Cellular Location
|
- Cytoplasm
- perinuclear region
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:9 |
| Locus
| 9q21.32 |
| SNPs
| RASEF |
| Gene Sequence
|
>2223 bp
ATGGAGGCGGATGGGGACGGAGAGGAGCTGGCCCGGCTGCGCTCAGTCTTCGCCGCCTGC
GACGCGAACCGCTCGGGGCGCCTGGAGCGCGAGGAGTTCCGGGCACTGTGCACGGAGCTG
CGGGTGCGGCCGGCCGACGCCGAGGCAGTATTCCAGCGGCTGGACGCCGACCGTGACGGC
GCCATCACCTTCCAGGAGTTCGCGCGTGGCTTCCTCGGGTCCCTCCGCGGGGGGCGGCGC
CGGGACTGGGGTCCTCTGGATCCCGCGCCCGCCGTGTCTGAGGCGGGGCCGGAGACACAC
GACAGCGAGGAGGACGAAGGCGACGAGGACGCGGCGGCGGCGCTGGCCACCTCGTGCGGC
CCGGCGAGTCCCGGCCGGGCTTGGCAGGATTTCCAGGCGCGACTTGGGGACGAAGCCAAG
TTCATTCCCAGAGAAGAGCAAGTTAGTACCTTGTACCAAAACATCAACCTTGTGGAGCCA
AGATTAATTCAGCCATATGAACATGTTATAAAGAACTTCATCCGTGAGATCAGACTTCAA
AGCACAGAAATGGAAAATTTGGCCATTGCGGTGAAGAGAGCCCAGGACAAGGCAGCTATG
CAGTTGAGTGAGTTGGAAGAGGAAATGGATCAGAGGATTCAGGCTGCAGAACATAAGACA
CGGAAAGACGAAAAACGCAAAGCTGAGGAAGCCCTCAGTGACCTCAGACGTCAGTATGAA
ACTGAAGTAGGAGATCTGCAGGTGACCATTAAAAAGCTAAGAAAGCTCGAAGAACAATCA
AAACGCGTAAGTCAAAAGGAAGATGTGGCTGCATTGAAAAAACAAATTTATGATTTATCA
ATGGAAAACCAGAAAGTTAAGAAAGACCTTTTAGAAGCACAGACAAACATAGCCTTTCTT
CAGAGTGAGTTAGATGCTTTGAAAAGTGATTATGCTGATCAGAGTCTGAATACTGAAAGG
GATCTGGAAATAATCCGAGCATACACAGAAGATCGAAATAGTCTTGAGAGGCAAATTGAA
ATACTCCAAACAGCTAACCGGAAGCTACATGACAGTAATGATGGCCTTAGAAGTGCCCTT
GAAAACAGTTATAGCAAGTTCAACAGATCTTTGCATATAAATAATATCTCACCAGGGAAT
ACAATTTCTAGAAGCAGTCCCAAATTCATTGGTCATTCCCCTCAACCTCTAGGCTATGAC
AGGTCATCCCGCTCTTCCTATGTGGATGAGGACTGTGACTCCCTGGCCCTCTGTGATCCT
CTGCAGAGGACAAATTGTGAAGTTGACAGCCTGCCTGAAAGCTGCTTCGACAGCGGCTTG
TCTACCTTGAGAGATCCCAATGAGTATGACTCAGAAGTGGAATACAAGCACCAGAGGGGA
TTTCAGAGGTCACACGGGGTGCAGGAGAGCTTTGGAGGTGATGCTTCAGACACAGATGTT
CCTGACATAAGGGATGAAGAGACATTTGGTTTAGAAGATGTGGCTTCCGTCTTAGACTGG
AAGCCCCAAGGGTCTGTTAGTGAAGGCAGCATTGTTAGTTCATCAAGAAAGCCCATCTCA
GCACTCTCGCCCCAGACAGACCTGGTAGATGACAACGCTAAATCTTTTAGCTCACAGAAG
GCTTACAAGATTGTACTTGCTGGGGACGCTGCAGTGGGGAAGTCTAGTTTCCTCATGAGA
CTTTGCAAGAATGAATTTCGAGAAAATATAAGCGCCACCCTGGGAGTTGATTTCCAAATG
AAAACCCTCATTGTGGATGGAGAACGAACAGTTCTGCAGCTCTGGGATACAGCTGGTCAG
GAGAGATTCAGAAGTATTGCCAAGTCTTACTTCAGAAAGGCAGATGGTGTTTTGCTGCTG
TATGATGTTACATGTGAGAAAAGCTTTCTTAACATACGAGAATGGGTAGATATGATTGAG
GATGCAGCCCATGAGACTGTTCCCATTATGCTGGTAGGAAACAAGGCTGACATTCGTGAC
ACTGCTGCTACAGAGGGACAAAAATGTGTCCCAGGGCACTTTGGAGAGAAACTGGCCATG
ACGTATGGGGCATTATTCTGTGAAACAAGTGCCAAAGATGGTTCTAACATAGTGGAGGCT
GTTCTGCACCTTGCTCGAGAAGTGAAAAAGAGAACTGACAAGGATGACAGCAGATCCATT
ACCAATCTAACCGGGACCAATTCCAAAAAGTCACCACAGATGAAGAATTGTTGCAATGGC
TAA
|
| Protein Properties |
| Number of Residues
| 740 |
| Molecular Weight
| 82878.3 |
| Theoretical pI
| 4.73 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ras and EF-hand domain-containing protein
MEADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDG
AITFQEFARGFLGSLRGGRRRDWGPLDPAPAVSEAGPETHDSEEDEGDEDAAAALATSCG
PASPGRAWQDFQARLGDEAKFIPREEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQ
STEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYE
TEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFL
QSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSAL
ENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDP
LQRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDV
PDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQK
AYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQ
ERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRD
TAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSI
TNLTGTNSKKSPQMKNCCNG
|
| External Links |
| GenBank ID Protein
| 40255119 |
| UniProtKB/Swiss-Prot ID
| Q8IZ41 |
| UniProtKB/Swiss-Prot Entry Name
| RASEF_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_152573.2 |
| GeneCard ID
| RASEF |
| GenAtlas ID
| RASEF |
| HGNC ID
| HGNC:26464 |
| References |
| General References
| Not Available |