| Identification |
|---|
| HMDB Protein ID
| CDBP03722 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ras-related protein Rab-5A |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| RAB5A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in GTP binding |
| Specific Function
| Required for the fusion of plasma membranes and early endosomes |
| GO Classification
|
| Function |
| gtp binding |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| Process |
| establishment of localization |
| transport |
| protein transport |
| biological regulation |
| regulation of biological process |
| regulation of cellular process |
| signal transduction |
| intracellular signal transduction |
| small gtpase mediated signal transduction |
|
| Cellular Location
|
- Cell membrane
- Lipid-anchor
- Lipid-anchor
- Melanosome
- Cytoplasmic side
- Early endosome membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3p24-p22 |
| SNPs
| RAB5A |
| Gene Sequence
|
>648 bp
ATGGCTAGTCGAGGCGCAACAAGACCCAACGGGCCAAATACGGGAAATAAAATATGCCAG
TTCAAACTAGTACTTCTGGGAGAGTCCGCTGTTGGCAAATCAAGCCTAGTGCTTCGTTTT
GTGAAAGGCCAATTTCATGAATTTCAAGAGAGTACCATTGGGGCTGCTTTTCTAACCCAA
ACTGTATGTCTTGATGACACTACAGTAAAGTTTGAAATATGGGATACAGCTGGTCAAGAA
CGATACCATAGCCTAGCACCAATGTACTACAGAGGAGCACAAGCAGCCATAGTTGTATAT
GATATCACAAATGAGGAGTCCTTTGCAAGAGCAAAAAATTGGGTTAAAGAACTTCAGAGG
CAAGCAAGTCCTAACATTGTAATAGCTTTATCGGGAAACAAGGCCGACCTAGCAAATAAA
AGAGCAGTAGATTTCCAGGAAGCACAGTCCTATGCAGATGACAATAGTTTATTATTCATG
GAGACATCCGCTAAAACATCAATGAATGTAAATGAAATATTCATGGCAATAGCTAAAAAA
TTGCCAAAGAATGAACCACAAAATCCAGGAGCAAATTCTGCCAGAGGAAGAGGAGTAGAC
CTTACCGAACCCACACAACCAACCAGGAATCAGTGTTGTAGTAACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 215 |
| Molecular Weight
| 23658.5 |
| Theoretical pI
| 8.31 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ras-related protein Rab-5A
MASRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQ
TVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQR
QASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKK
LPKNEPQNPGANSARGRGVDLTEPTQPTRNQCCSN
|
| External Links |
|---|
| GenBank ID Protein
| 20379048 |
| UniProtKB/Swiss-Prot ID
| P20339 |
| UniProtKB/Swiss-Prot Entry Name
| RAB5A_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF498936 |
| GeneCard ID
| RAB5A |
| GenAtlas ID
| RAB5A |
| HGNC ID
| HGNC:9783 |
| References |
|---|
| General References
| Not Available |